irinotecan - PubChem

irinotecan - Compound Summary (CID 74990) Also known as: Irinotecan hydrochloride, Topotecin, Campto, CPT 11, CPT-11, 100286-90-6, Camptothecin 11 hydrochloride, Camptothecin analog, NSC616348 Molecular Formula: C₃₃H₃₉ClN₄O₆ Molecular Weight: 623.13896 InChIKey: GURKHSYORGJETM-WAQYZQTGSA-N Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death. From: DrugBank View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 2D SDF: Display 2D SDF: Save BioActivity, this compound BioActivity, with similar compounds
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