71759660 -OEChem-05062403382D 78 83 0 1 0 0 0 0 0999 V2000 8.1286 4.4594 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -2.5406 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 0.8258 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 -0.0406 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.6286 -5.0794 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 2.4594 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 7.2626 -1.0406 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 2.7642 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.5406 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6286 -5.0794 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 0.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 1.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 0.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 0.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 2.9594 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 6.3966 2.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -0.5406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -0.5406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 1.1547 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 2.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 1.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 0.2027 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -2.0406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 1.8680 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 2.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 0.0874 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 0.9257 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 1.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 2.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -3.5406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 0.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 2.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 1.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3196 -4.1284 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9376 -4.1284 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -0.0858 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3685 -3.8194 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8887 -3.8194 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 -0.5406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 0.8768 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 1.5671 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 0.3518 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.0420 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 1.0420 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 0.3518 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 3.2694 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 -1.1232 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 -0.4329 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 -0.4329 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 -1.1232 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2577 3.3535 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3932 3.4344 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5961 3.4344 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0505 4.5420 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6520 3.8518 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 -0.2949 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 2.3740 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 -0.4797 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 5.0794 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6655 -2.2306 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3237 1.1494 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 3.5794 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1296 2.7694 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1296 1.1494 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 0.1691 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 -0.6510 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 -0.3406 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5601 -3.2297 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7789 -3.6278 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1769 -4.4090 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0803 -4.4090 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4783 -3.6278 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6971 -3.2297 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2827 -1.0775 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1296 -0.8506 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9027 -0.0036 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 23 1 0 0 0 0 1 61 1 0 0 0 0 2 25 2 0 0 0 0 3 29 1 0 0 0 0 3 38 1 0 0 0 0 4 33 1 0 0 0 0 4 41 1 0 0 0 0 5 10 1 0 0 0 0 5 36 1 0 0 0 0 6 12 1 0 0 0 0 6 16 1 0 0 0 0 6 21 1 0 0 0 0 7 18 1 0 0 0 0 7 19 1 0 0 0 0 7 25 1 0 0 0 0 8 17 1 0 0 0 0 8 22 1 0 0 0 0 8 53 1 0 0 0 0 9 25 1 0 0 0 0 9 32 1 0 0 0 0 9 62 1 0 0 0 0 10 37 2 0 0 0 0 11 12 1 0 0 0 0 11 13 1 0 0 0 0 11 14 1 0 0 0 0 11 15 1 0 0 0 0 12 42 1 0 0 0 0 12 43 1 0 0 0 0 13 17 2 0 0 0 0 13 20 1 0 0 0 0 14 18 1 0 0 0 0 14 44 1 0 0 0 0 14 45 1 0 0 0 0 15 19 1 0 0 0 0 15 46 1 0 0 0 0 15 47 1 0 0 0 0 16 17 1 0 0 0 0 16 23 1 6 0 0 0 16 48 1 0 0 0 0 18 49 1 0 0 0 0 18 50 1 0 0 0 0 19 51 1 0 0 0 0 19 52 1 0 0 0 0 20 22 2 0 0 0 0 20 24 1 0 0 0 0 21 27 1 0 0 0 0 21 54 1 0 0 0 0 21 55 1 0 0 0 0 22 26 1 0 0 0 0 23 56 1 0 0 0 0 23 57 1 0 0 0 0 24 28 2 0 0 0 0 24 58 1 0 0 0 0 26 29 2 0 0 0 0 26 59 1 0 0 0 0 27 30 2 0 0 0 0 27 31 1 0 0 0 0 28 29 1 0 0 0 0 28 60 1 0 0 0 0 30 33 1 0 0 0 0 30 63 1 0 0 0 0 31 34 2 0 0 0 0 31 64 1 0 0 0 0 32 36 2 0 0 0 0 32 37 1 0 0 0 0 33 35 2 0 0 0 0 34 35 1 0 0 0 0 34 65 1 0 0 0 0 35 66 1 0 0 0 0 36 39 1 0 0 0 0 37 40 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 38 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 39 72 1 0 0 0 0 40 73 1 0 0 0 0 40 74 1 0 0 0 0 40 75 1 0 0 0 0 41 76 1 0 0 0 0 41 77 1 0 0 0 0 41 78 1 0 0 0 0 M END > 71759660 > 1 > 902 > 7 > 3 > 6 > AAADcfB7uAAAAAAAAAAAAAAAAAAAAWLAAAA8eIEAAAAAAFgB/AAAHgAUCAAADizhngYzxvPZlgCpA6RyVgCCiCAlMiAomSG/fNqOdvrEsbuUcahu1pvY6Wew0PMPoAABAgACAABAAAIEAAQAAAAAAAAAAA== > (1R)-N-(3,5-dimethylisoxazol-4-yl)-1-(hydroxymethyl)-7-methoxy-2-[(3-methoxyphenyl)methyl]spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1R)-N-(3,5-dimethyl-4-isoxazolyl)-1-(hydroxymethyl)-7-methoxy-2-[(3-methoxyphenyl)methyl]-1'-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]carboxamide > (1R)-N-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(hydroxymethyl)-7-methoxy-2-[(3-methoxyphenyl)methyl]spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1R)-N-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(hydroxymethyl)-7-methoxy-2-[(3-methoxyphenyl)methyl]spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1R)-N-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(hydroxymethyl)-7-methoxy-2-[(3-methoxyphenyl)methyl]spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1R)-N-(3,5-dimethylisoxazol-4-yl)-2-m-anisyl-7-methoxy-1-methylol-spiro[3,9-dihydro-1H-beta-carboline-4,4'-piperidine]-1'-carboxamide > InChI=1S/C31H37N5O5/c1-19-28(20(2)41-34-19)33-30(38)35-12-10-31(11-13-35)18-36(16-21-6-5-7-22(14-21)39-3)26(17-37)29-27(31)24-9-8-23(40-4)15-25(24)32-29/h5-9,14-15,26,32,37H,10-13,16-18H2,1-4H3,(H,33,38)/t26-/m0/s1 > DPARMXWTZUJMJF-SANMLTNESA-N > 3.2 > 559.27946930 > C31H37N5O5 > 559.7 > CC1=C(C(=NO1)C)NC(=O)N2CCC3(CC2)CN(C(C4=C3C5=C(N4)C=C(C=C5)OC)CO)CC6=CC(=CC=C6)OC > CC1=C(C(=NO1)C)NC(=O)N2CCC3(CC2)CN([C@H](C4=C3C5=C(N4)C=C(C=C5)OC)CO)CC6=CC(=CC=C6)OC > 116 > 559.27946930 > 0 > 41 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 10 37 8 13 17 8 13 20 8 16 23 6 20 22 8 20 24 8 22 26 8 24 28 8 26 29 8 27 30 8 27 31 8 28 29 8 30 33 8 31 34 8 32 36 8 32 37 8 33 35 8 34 35 8 5 10 8 5 36 8 8 17 8 8 22 8 $$$$