71758944 -OEChem-04252407162D 65 69 0 1 0 0 0 0 0999 V2000 12.4587 0.1471 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 3.6471 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -2.7671 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 0.0135 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -1.2671 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.6471 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 5.4503 1.9518 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.7671 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 0.1471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5555 -0.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9697 -0.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 0.6471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 0.6471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 2.1471 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 6.3966 1.6471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 0.3424 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 2.1471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 1.1471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.1471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -2.2671 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 -0.6096 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 1.0556 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 1.6471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 -0.7249 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 0.1134 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -3.7671 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 2.1471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 0.6471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -4.2671 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -4.2671 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 1.6471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 0.1471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 0.6471 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -0.8981 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1171 -0.1216 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1171 -0.9984 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4081 -0.9984 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4081 -0.1216 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 0.0645 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 0.7548 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 2.4571 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2577 2.5412 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3932 2.6221 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5961 2.6221 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0505 3.7297 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6520 3.0394 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 -1.1073 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 1.5617 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6655 -2.4571 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 -1.2920 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 4.2671 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6655 -3.4571 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 2.7671 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3237 0.3371 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6846 -4.8040 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -4.5771 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3046 -3.7302 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9526 -3.7302 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7256 -4.5771 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5726 -4.8040 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1296 1.9571 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 -0.4729 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 -0.6432 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 -1.4633 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 -1.1529 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 33 1 0 0 0 0 2 19 1 0 0 0 0 2 51 1 0 0 0 0 3 20 2 0 0 0 0 4 25 1 0 0 0 0 4 34 1 0 0 0 0 5 10 1 0 0 0 0 5 11 1 0 0 0 0 5 20 1 0 0 0 0 6 12 1 0 0 0 0 6 14 1 0 0 0 0 6 17 1 0 0 0 0 7 15 1 0 0 0 0 7 18 1 0 0 0 0 7 42 1 0 0 0 0 8 20 1 0 0 0 0 8 26 1 0 0 0 0 8 49 1 0 0 0 0 9 10 1 0 0 0 0 9 11 1 0 0 0 0 9 12 1 0 0 0 0 9 13 1 0 0 0 0 10 35 1 0 0 0 0 10 36 1 0 0 0 0 11 37 1 0 0 0 0 11 38 1 0 0 0 0 12 39 1 0 0 0 0 12 40 1 0 0 0 0 13 15 2 0 0 0 0 13 16 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 6 0 0 0 14 41 1 0 0 0 0 16 18 2 0 0 0 0 16 21 1 0 0 0 0 17 23 1 0 0 0 0 17 43 1 0 0 0 0 17 44 1 0 0 0 0 18 22 1 0 0 0 0 19 45 1 0 0 0 0 19 46 1 0 0 0 0 21 24 2 0 0 0 0 21 47 1 0 0 0 0 22 25 2 0 0 0 0 22 48 1 0 0 0 0 23 27 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 24 50 1 0 0 0 0 26 29 1 0 0 0 0 26 30 1 0 0 0 0 26 52 1 0 0 0 0 27 31 1 0 0 0 0 27 53 1 0 0 0 0 28 32 2 0 0 0 0 28 54 1 0 0 0 0 29 55 1 0 0 0 0 29 56 1 0 0 0 0 29 57 1 0 0 0 0 30 58 1 0 0 0 0 30 59 1 0 0 0 0 30 60 1 0 0 0 0 31 33 2 0 0 0 0 31 61 1 0 0 0 0 32 33 1 0 0 0 0 32 62 1 0 0 0 0 34 63 1 0 0 0 0 34 64 1 0 0 0 0 34 65 1 0 0 0 0 M END > 71758944 > 1 > 725 > 5 > 3 > 5 > AAADceB7sQAAAAAAAAAAAAAAAABYAWAAAAA8YIAAAAAAAFgB9AAAHwAQCAAADizhng4zxvPJlgCoAyRiVACCiCAhIiAImaA+bJiOduLE8ZuUcChu1hvY6AeQ0PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > (1R)-2-[(4-fluorophenyl)methyl]-1-(hydroxymethyl)-N-isopropyl-7-methoxy-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]-1'-carboxamide > (1R)-2-[(4-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-N-propan-2-yl-1'-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]carboxamide > (1R)-2-[(4-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-N-propan-2-ylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]-1'-carboxamide > (1R)-2-[(4-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-N-propan-2-ylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]-1'-carboxamide > (1R)-2-[(4-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-N-propan-2-yl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]-1'-carboxamide > (1R)-2-(4-fluorobenzyl)-N-isopropyl-7-methoxy-1-methylol-spiro[3,9-dihydro-1H-beta-carboline-4,3'-azetidine]-1'-carboxamide > InChI=1S/C26H31FN4O3/c1-16(2)28-25(33)31-14-26(15-31)13-30(11-17-4-6-18(27)7-5-17)22(12-32)24-23(26)20-9-8-19(34-3)10-21(20)29-24/h4-10,16,22,29,32H,11-15H2,1-3H3,(H,28,33)/t22-/m0/s1 > LYHJYSCMOBCJFS-QFIPXVFZSA-N > 2.6 > 466.23801903 > C26H31FN4O3 > 466.5 > CC(C)NC(=O)N1CC2(C1)CN(C(C3=C2C4=C(N3)C=C(C=C4)OC)CO)CC5=CC=C(C=C5)F > CC(C)NC(=O)N1CC2(C1)CN([C@H](C3=C2C4=C(N3)C=C(C=C4)OC)CO)CC5=CC=C(C=C5)F > 80.8 > 466.23801903 > 0 > 34 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 13 15 8 13 16 8 14 19 6 16 18 8 16 21 8 18 22 8 21 24 8 22 25 8 23 27 8 23 28 8 24 25 8 27 31 8 28 32 8 31 33 8 32 33 8 7 15 8 7 18 8 $$$$