71680
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
8
8
8
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
4
4
5
5
5
5
6
6
6
7
7
7
8
8
8
9
9
9
10
10
10
11
11
11
12
12
12
13
13
13
14
14
14
15
15
17
17
18
18
18
19
19
19
20
20
20
21
21
21
22
22
22
23
24
25
25
16
23
56
24
25
57
6
7
11
26
8
13
27
9
16
28
12
14
20
10
18
21
15
19
29
15
30
31
17
24
32
17
33
34
16
35
36
37
38
41
42
22
39
40
23
43
44
45
46
47
48
49
50
23
51
52
53
25
54
55
2
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
5
6
7
11
26
3
1
6
5
8
13
27
1
1
7
5
9
16
28
1
1
8
6
12
14
20
3
1
9
7
10
18
21
3
1
10
9
15
19
29
1
1
12
8
17
24
32
3
1
23
2
19
22
53
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
-0.1389
-6.1957
5.3386
6.0461
-0.3401
1.1264
-0.8725
2.0759
-2.3834
-3.2551
-1.2311
3.1595
1.7609
1.3377
-2.6638
0.0794
3.227
-2.5498
-4.7149
2.6732
-2.8978
-4.0074
-4.832
4.5003
4.7575
-0.3638
1.1331
-0.7881
-3.2845
-1.202
-0.8688
2.8265
1.6306
1.3153
1.0448
1.9709
-3.2699
-2.6946
-2.082
-2.0296
3.7179
3.7595
-5.2605
-5.2475
3.3196
3.2629
1.885
-2.4634
-2.6599
-3.9807
-4.0513
-4.4561
-4.5168
4.7002
4.0206
-6.4943
6.0591
2.4968
0.3789
-0.3994
1.8481
-1.0472
-1.3504
0.1875
-0.1136
0.515
-0.7835
-2.2662
-0.5601
-2.4505
1.1282
-1.9839
1.3769
-2.071
1.1204
-0.5696
0.1909
1.5367
1.3365
0.0604
0.0802
1.3389
-0.8333
-1.7119
-0.0494
-1.0678
-2.5452
-3.1321
-0.3589
-3.4453
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1.0248
2.019
-2.8769
-1.8214
0.4698
2.0834
-2.5591
-2.3699
-1.5225
0.0499
1.0751
-0.6511
0.3873
2.5298
1.2037
1.68
1.7037
2.1353
-0.6544
1.1011
2.1054
1.0097
2.1291
-1.1136
1.4094
-0.2985
0.9927
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0.6469
0.381
0.15
0.0658
-0.6519
0.4833
0.8572
-0.2407
-1.7651
-1.618
1.2622
1.1462
0.4634
1.2644
0.9788
-1.5275
-1.9422
-1.7529
-1.4116
0.2144
1.6747
-0.0567
1.3832
1.2013
0.0797
-0.1313
1.1491
1.6049
0.9256
1.3315
-0.4273
-0.25
-0.9726
-1.7433
-2.1438
-2.5009
-1.4773
-2.6345
-1.5759
2.2954
0.6588
1.9135
2.3299
1.019
0.7322
0.0618
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0001180000000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
75.6409
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
50.895
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10 15 18113613521652524392
10493431 412 18412826905972881747
10675989 125 16600933719060608877
11132069 177 18333729113217781646
11796584 16 15647061460421596873
12236239 1 17988923371039015639
12251169 10 18410859854291279215
12390115 104 18270123543168551056
12403259 118 17530682087041810677
12403259 415 18409444752656091620
12403814 3 18040436577516653245
12553582 1 18261399948534890917
12596602 18 17988927781812219051
12633257 1 18040444321200392931
12788726 201 16916511332858319936
12892183 10 18340493261839606633
13140716 1 18191593162378755241
13224815 77 18334296422594650326
13675066 3 18040713623875770254
14178342 30 18337955704813926611
14223421 5 18265324020051704638
14341114 176 18343867718743775048
14341114 328 17989486320628505464
14765038 42 18342748437138858145
14787075 74 17918270961319438657
14790565 3 18264210390946041732
14840074 17 18114187470837764884
14863182 85 18260276226625308374
14955137 171 18261688029350760844
15163728 17 15050910585358245107
15183329 4 11383843679650338520
15196674 1 18335976463450759310
15209294 21 18202567263439551891
15788980 27 17749105578173705900
16945 1 18335140860372605269
17349148 13 17385445406154051420
17980427 23 17989489658351350997
1813 80 17240771652774694052
18785283 64 17823990128102346172
19784866 170 18408317805019886594
19784866 240 13406791108052782745
19862831 5 11024102153152908766
200 152 12251904793526381999
20261772 1 18335706022260771731
20739085 24 18191320294263434839
21033648 29 18264188275542360000
21267235 1 18260556584651896542
21421861 104 18041835087466999290
21637258 2 15140962902607769803
21756936 100 17560508612515378392
22182313 1 18116431445120602399
23184049 59 18337398149661117439
23559900 14 18268976760745736305
25147074 1 18118690056557188197
2748010 2 17901662666050861614
2838139 119 15554163667035051561
296302 2 18060135444492379158
34797466 226 16486700276346039788
34934 24 18335968831315051310
350125 39 18338515373312009477
3633792 109 18339626916039954981
392239 28 18339348752076964384
5104073 3 18115580427236374936
542803 24 17489868241240835522
633830 44 17632015247636853326
7495541 125 14707212145097474398
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
491.01
11.38
2.33
1.34
2.13
0.51
0.11
-2.92
-5.01
0.7
0
-0.45
-0.55
0.2
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1044.843
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
271
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
66
50
54
47
34
6
7
74
40
73
67
28
63
44
59
38
2
27
19
45
51
23
26
62
22
35
15
39
69
56
64
65
71
60
14
13
61
72
5
48
25
11
29
55
57
21
68
36
30
31
10
70
46
32
18
20
53
42
41
52
33
24
12
16
58
43
37
8
3
17
4
49
9
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
13
1 -0.57
12 0.06
14 0.06
16 0.45
2 -0.68
23 0.28
24 0.45
25 0.34
3 -0.57
4 -0.68
56 0.4
57 0.4
7 0.06
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
4
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
10
1 1 acceptor
1 2 acceptor
1 2 donor
1 3 acceptor
1 4 acceptor
1 4 donor
5 6 8 12 13 17 rings
6 5 6 7 8 14 16 rings
6 5 7 9 10 11 15 rings
6 9 10 18 19 22 23 rings
25
8
4
4
0
0
0
0
1
12