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Compound Summary for: CID 71353


Also known as: 119356-77-3; Dapoxetina; Dapoxetinum; Dapoxetinum [INN-Latin]; Dapoxetina [INN-Spanish]
Molecular Formula: C21H23NO   Molecular Weight: 305.41342   InChIKey: USRHYDPUVLEVMC-FQEVSTJZSA-N
Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation in December 2004. In October 2005, the company received a FDA Non-Approvable letter from the FDA, at which time they planned to work with regulators to address outstanding questions.   From: DrugBank
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