70680592 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 16 8 8 8 8 8 7 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 4 4 5 6 7 7 7 8 8 9 9 9 10 10 10 11 11 12 12 14 14 14 8 11 12 26 13 27 15 28 13 15 8 10 19 9 16 12 13 17 11 15 18 20 21 14 22 23 24 25 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 8 1 7 9 16 1 1 9 8 12 13 17 1 1 10 7 11 15 18 3 1 12 2 9 14 22 1 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Conformer RMSD 7 2012.11.26 0.6 Diverse Conformer ID List 6 2012.11.26 1 54 63 64 66 51 38 40 72 69 31 12 73 65 34 46 45 42 39 79 80 35 53 4 44 71 25 29 52 59 11 60 75 61 20 3 14 78 70 2 41 49 16 24 37 32 18 67 62 47 36 13 77 57 58 22 55 23 68 56 8 33 74 21 50 28 27 17 26 6 10 7 19 15 43 30 48 5 76 9 Charge MMFF94 Partial 2 1.9.0 OEChem openeye.com 2012.11.26 18 1 -0.46 10 0.33 11 0.23 12 0.28 13 0.66 15 0.66 19 0.36 2 -0.68 26 0.4 27 0.5 28 0.5 3 -0.65 4 -0.65 5 -0.57 6 -0.57 7 -0.9 8 0.5 9 0.06 Count Effective Rotor 7 1.9.0 OEChem ncbi.nlm.nih.gov 2012.11.26 5 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.3 OEShape openeye.com 2012.11.26 11 1 2 acceptor 1 2 donor 1 3 acceptor 1 4 acceptor 1 5 acceptor 1 6 acceptor 1 7 cation 1 7 donor 3 3 5 13 anion 3 4 6 15 anion 5 1 7 8 10 11 rings 15 4 3 1 0 0 0 0 1 1