70679361 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 9 8 8 8 8 8 8 7 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 4 4 5 5 6 6 7 8 8 8 9 9 9 10 10 11 11 12 13 14 14 15 16 16 16 12 12 13 9 24 11 25 13 26 14 27 15 10 15 23 10 11 17 13 18 12 19 14 20 21 22 16 28 29 30 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 9 3 11 10 17 2 1 10 8 13 9 18 2 1 11 4 9 12 19 1 1 12 1 11 2 14 2 1 13 2 10 5 20 2 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 Conformer RMSD 7 2012.11.26 0.6 Diverse Conformer ID List 6 2012.11.26 1 4 9 13 2 11 6 7 10 12 5 8 3 Charge MMFF94 Partial 2 1.9.0 OEChem openeye.com 2012.11.26 21 1 -0.34 10 0.3 11 0.28 12 0.62 13 0.56 14 0.28 15 0.57 16 0.06 2 -0.56 23 0.37 24 0.4 25 0.4 26 0.4 27 0.4 3 -0.68 4 -0.68 5 -0.68 6 -0.68 7 -0.57 8 -0.73 9 0.28 Count Effective Rotor 7 1.9.0 OEChem ncbi.nlm.nih.gov 2012.11.26 4.2 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.3 OEShape openeye.com 2012.11.26 12 1 2 acceptor 1 3 acceptor 1 3 donor 1 4 acceptor 1 4 donor 1 5 acceptor 1 5 donor 1 6 acceptor 1 6 donor 1 7 acceptor 1 8 donor 6 2 9 10 11 12 13 rings 16 5 5 0 0 0 0 0 1 2