70679359 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 16 8 8 8 7 7 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 3 4 5 5 5 6 6 6 7 7 7 8 8 8 9 9 10 10 12 12 13 13 13 13 14 14 14 15 16 16 17 9 27 11 18 34 18 7 10 25 11 12 26 8 11 19 9 20 21 10 22 23 24 15 17 14 15 28 29 16 30 31 32 17 18 33 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 2 1 1 7 5 8 11 19 1 1 9 1 8 10 22 1 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 Conformer RMSD 7 2012.11.26 0.8 Diverse Conformer ID List 6 2012.11.26 1 14 11 9 4 12 13 10 5 3 16 2 7 8 6 17 15 Charge MMFF94 Partial 2 1.9.0 OEChem openeye.com 2012.11.26 23 1 -0.41 10 0.27 11 0.57 12 0.11 13 0.14 14 0.14 15 -0.29 16 -0.12 17 -0.15 18 0.71 2 -0.57 25 0.36 26 0.37 27 0.18 3 -0.65 32 0.15 33 0.15 34 0.5 4 -0.57 5 -0.9 6 -0.54 7 0.33 9 0.23 Count Effective Rotor 7 1.9.0 OEChem ncbi.nlm.nih.gov 2012.11.26 5.4 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.3 OEShape openeye.com 2012.11.26 9 1 2 acceptor 1 3 acceptor 1 4 acceptor 1 5 cation 1 5 donor 1 6 donor 3 3 4 18 anion 5 5 7 8 9 10 rings 6 12 13 14 15 16 17 rings 18 2 2 0 0 0 0 0 1 6