70679356 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 3 4 5 6 7 7 8 9 9 10 11 11 12 12 12 13 13 13 14 14 14 15 15 15 16 16 16 17 17 17 18 18 18 19 19 19 20 20 20 21 21 21 22 22 23 23 23 25 25 26 26 26 28 28 28 29 29 29 30 31 31 31 32 33 33 33 34 34 34 35 35 35 38 38 39 39 40 40 40 42 42 43 43 43 44 44 45 45 46 46 46 47 47 48 50 50 51 51 52 52 54 54 55 55 56 56 57 57 58 59 59 60 60 24 27 38 101 36 37 41 49 109 49 53 112 53 61 113 20 27 66 24 26 70 23 37 76 30 32 79 28 36 82 41 43 90 29 94 95 47 102 103 21 24 62 22 63 64 25 32 27 34 65 30 39 36 38 67 35 41 68 31 37 69 42 33 71 72 73 40 74 75 49 77 78 44 80 81 83 84 45 85 47 86 87 48 88 46 53 89 51 52 48 91 50 92 93 96 97 98 56 57 54 99 55 100 58 104 58 105 59 106 60 107 108 61 110 61 111 2 2 1 1 2 2 2 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 2 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 2 1 1 1 2 1 2 1 1 1 1 1 2 1 1 2 1 1 1 20 12 21 24 62 1 1 23 14 34 27 65 2 1 26 13 38 36 67 2 1 28 16 35 41 68 1 1 29 18 31 37 69 1 1 43 17 46 53 89 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 6.3246 4.6318 8.6388 9.5708 6.5422 12.5528 3.6067 3.9639 13.5779 13.2207 14.2922 6.2781 7.6138 6.8994 4.6783 9.928 11.2637 8.4993 11.792 5.9674 4.9889 4.6783 5.9209 6.6353 3.732 8.2816 5.6103 10.9065 8.1886 3.732 8.8564 5.2619 9.8349 5.2531 11.2171 9.2601 7.2101 7.971 2.866 10.5028 11.5743 2.866 11.9315 12.1957 2 11.6208 11.4813 2 4.2746 12.2887 12.5063 12.8635 12.91 13.4848 13.842 13.2672 11.978 14.1527 13.935 12.6459 13.6244 5.5534 4.9684 4.3751 6.1135 6.8848 8.4742 10.7139 7.7745 7.8064 8.3301 9.0877 5.8819 10.3613 9.6037 7.3135 5.7794 5.0218 4.8709 11.1966 10.6033 9.7354 7.424 7.5884 2.866 9.9764 10.734 2.866 11.3248 10.657 1.4631 11.0739 11.2383 9.1059 8.0852 11.5019 12.0951 1.4631 12.0923 12.6709 8.4462 12.3986 11.3779 13.6774 14.2561 13.4598 11.3714 14.7593 3 14.5417 12.4533 14.1845 14.0996 -0.1198 3.0637 -1.4021 1.4494 6.1214 -0.5773 5.5028 3.808 -3.0164 -1.3216 -6.406 2.5256 1.037 4.4266 -1.1911 -0.2454 -1.734 6.5339 5.4577 1.5751 1.3688 0.4183 4.2204 0.8308 0.1136 0.2927 3.2699 -0.0392 5.5834 -0.8864 4.8391 -0.3864 5.0453 4.9647 0.9113 0.4989 5.3772 -0.6578 0.6136 4.301 -0.7835 -1.3864 -2.4783 1.1176 0.1136 -3.4288 4.5072 -0.8864 4.7585 -4.1731 2.0681 0.3733 -2.2721 2.2743 0.5795 -3.9669 -5.1236 1.53 -4.7112 -5.868 -5.6617 2.0365 1.9885 1.4562 4.8097 2.6534 0.882 -0.6285 6.0448 1.6263 4.5114 4.2638 -0.3864 5.3729 5.6205 3.9652 5.2924 5.54 -1.7805 1.531 0.9987 -0.8347 -0.3658 -1.1457 1.2336 3.9733 3.7257 -2.0064 -2.6062 -1.8619 0.4236 -3.1368 -3.9167 6.6617 6.9954 3.8875 4.4198 -1.1964 2.5295 -0.2161 -1.9915 5.5856 5.9192 2.8636 0.118 -3.3776 -5.2515 1.6578 5.3749 -4.5834 -6.4573 -2.8885 -6.9954 8 8 6 8 8 6 8 8 6 5 5 8 8 8 6 8 8 8 8 8 8 8 8 8 8 8 8 8 15 15 20 22 22 23 25 25 26 28 29 30 39 42 43 44 44 45 50 50 51 52 54 55 56 57 59 60 30 32 12 25 32 14 30 39 13 16 18 42 45 48 17 51 52 48 56 57 54 55 58 58 59 60 61 61 0 Compound Canonicalized 5 2012.11.26 1 Compound Complexity 7 E_COMPLEXITY 3.408 Cactvs xemistry.com 2012.11.26 1470 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.408 Cactvs xemistry.com 2012.11.26 13 Count Hydrogen Bond Donor 5 E_NHDONORS 3.408 Cactvs xemistry.com 2012.11.26 12 Count Rotatable Bond 5 E_NROTBONDS 3.408 Cactvs xemistry.com 2012.11.26 24 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.408 Cactvs xemistry.com 2012.11.26 00000371F07FFC000000000000000000000000000001600000003060C000000000005801F400001E00100800000C2CE19E063CCEF2C99200A80335F75C0082802031222008D9A1BE6C980A76FEC291B394700866F611D8D807BFC9E08EA0000000000200004000000000040000000000000000 IUPAC Name Allowed 1 2.2.0 LexiChem openeye.com 2012.11.26 (3S)-4-[[(1S)-2-[[(1S)-2-[[(1S)-1-benzyl-2-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxo-butanoic acid IUPAC Name CAS-like Style 1 2.2.0 LexiChem openeye.com 2012.11.26 (3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-[[(2S)-2,6-diamino-1-oxohexyl]amino]-4-oxobutanoic acid IUPAC Name Preferred 1 2.2.0 LexiChem openeye.com 2012.11.26 (3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoic acid IUPAC Name Systematic 1 2.2.0 LexiChem openeye.com 2012.11.26 (3S)-3-[[(2S)-2,6-bis(azanyl)hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-3-(4-hydroxyphenyl)-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-3-phenyl-propan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanylidene-butanoic acid IUPAC Name Traditional 1 2.2.0 LexiChem openeye.com 2012.11.26 (3S)-4-[[(1S)-2-[[(1S)-2-[[(1S)-1-benzyl-2-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-2-keto-ethyl]amino]-2-keto-1-methylol-ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-keto-ethyl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-keto-butyric acid InChI Standard 1 1.0.4 InChI iupac.org 2012.11.26 InChI=1S/C42H52N8O11/c43-17-7-6-11-29(44)37(55)46-33(21-36(53)54)40(58)48-32(20-26-22-45-30-12-5-4-10-28(26)30)39(57)50-35(23-51)41(59)47-31(18-24-8-2-1-3-9-24)38(56)49-34(42(60)61)19-25-13-15-27(52)16-14-25/h1-5,8-10,12-16,22,29,31-35,45,51-52H,6-7,11,17-21,23,43-44H2,(H,46,55)(H,47,59)(H,48,58)(H,49,56)(H,50,57)(H,53,54)(H,60,61)/t29-,31-,32-,33-,34-,35-/m0/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.11.26 ORAWTQLGAVSURU-LXOXETEGSA-N Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 844.375555 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 C42H52N8O11 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 844.90928 SMILES Canonical 1 1.9.0 OEChem openeye.com 2012.11.26 C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=C(C=C2)O)C(=O)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)N SMILES Isomeric 1 1.9.0 OEChem openeye.com 2012.11.26 C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)N Topological Polar Surface Area 7 E_TPSA 3.408 Cactvs xemistry.com 2012.11.26 328 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 844.375555 61 6 6 0 0 0 0 0 1 64