70679355 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 14 1 18 1 1 2 3 4 4 5 6 7 7 8 9 9 10 11 11 12 12 12 13 13 13 14 14 14 14 15 15 15 16 16 16 17 17 17 18 18 18 18 19 19 19 20 20 20 21 21 21 22 22 22 23 23 23 24 24 24 25 25 25 26 26 27 27 27 31 31 32 32 32 33 33 33 34 35 35 36 36 36 37 39 39 39 40 40 41 41 43 43 44 44 44 45 45 47 47 48 49 49 49 50 50 51 51 52 52 54 54 55 55 56 56 57 57 58 59 59 60 60 28 29 30 40 105 38 42 46 108 46 53 114 53 61 115 20 30 73 25 28 74 21 75 76 77 29 32 81 34 37 86 36 38 89 35 94 95 96 42 44 98 23 29 62 22 28 63 24 64 65 26 66 67 27 68 69 30 33 70 31 37 35 71 72 34 41 38 40 78 46 79 80 43 83 84 39 42 82 85 45 87 88 90 91 47 92 48 93 49 53 97 51 52 48 99 100 50 101 102 56 57 54 103 55 104 58 106 58 107 59 109 60 110 111 61 112 61 113 2 2 2 1 1 2 2 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 2 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 2 1 1 1 2 1 2 1 1 1 1 1 2 1 1 2 1 1 1 20 12 23 29 62 1 1 21 14 22 28 63 1 1 25 13 33 30 70 2 1 32 15 40 38 78 2 1 36 17 39 42 82 1 1 44 19 49 53 97 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 6.5422 6.3246 4.6318 8.6388 9.5708 12.5528 3.6067 3.9639 13.5779 13.2207 14.2922 6.2781 6.8994 8.4993 7.6138 4.6783 9.928 11.792 11.2637 5.9674 8.1886 8.8564 4.9889 9.8349 5.9209 4.6783 10.5028 7.2101 6.6353 5.6103 3.732 8.2816 5.2531 3.732 11.4813 10.9065 5.2619 9.2601 11.2171 7.971 2.866 11.5743 2.866 11.9315 12.1957 4.2746 2 2 11.6208 12.2887 12.5063 12.8635 12.91 13.4848 13.842 13.2672 11.978 14.1527 13.935 12.6459 13.6244 5.5534 7.7745 8.3301 9.0877 4.9684 4.3751 10.3613 9.6037 6.1135 9.9764 10.734 6.8848 7.3135 8.6919 9.0886 7.9099 8.4742 5.7794 5.0218 7.8064 10.7139 11.5019 12.0951 5.8819 4.8709 11.1966 10.6033 9.7354 7.424 7.5884 2.866 2.866 11.9846 12.3813 11.2026 11.3248 10.657 1.4631 1.4631 11.0739 11.2383 12.0923 12.6709 8.4462 13.6774 14.2561 3 13.4598 11.3714 14.7593 14.5417 12.4533 14.1845 14.0996 6.0575 -0.1837 2.9997 -1.4661 1.3855 -0.6412 5.4389 3.744 -3.0803 -1.3855 -6.47 2.4617 4.3627 6.47 0.9731 -1.2551 -0.3093 5.3938 -1.7979 1.5111 5.5194 4.7751 1.3049 4.9814 4.1565 0.3544 4.237 5.3132 0.7668 3.206 0.0497 0.2288 4.9008 -0.9503 4.4433 -0.1031 -0.4503 0.435 0.8474 -0.7218 0.5497 -0.8474 -1.4503 -2.5422 1.0536 4.6946 0.0497 -0.9503 -3.4928 -4.237 2.0042 0.3093 -2.336 2.2104 0.5155 -4.0308 -5.1876 1.4661 -4.7751 -5.9319 -5.7257 1.9726 5.9809 4.4475 4.1999 1.9246 1.3923 5.309 5.5566 4.7458 3.9094 3.6618 2.5895 3.9012 7.0593 6.2774 6.6626 0.8181 5.2284 5.476 1.5624 -0.6924 3.8236 4.3559 -0.4503 -1.8444 1.4671 0.9348 -0.8987 -0.4297 -1.2097 1.1697 -2.0703 5.9831 5.2012 5.5864 -2.6701 -1.9258 0.3597 -1.2603 -3.2007 -3.9807 2.4656 -0.28 -2.0554 2.7997 0.0541 5.311 -3.4415 -5.3154 1.5939 -4.6473 -6.5212 -2.9525 -7.0593 8 8 6 5 6 8 8 8 8 6 8 5 8 8 6 8 8 8 8 8 8 8 8 8 8 8 8 8 16 16 20 21 25 26 26 31 31 32 34 36 41 43 44 45 45 47 50 50 51 52 54 55 56 57 59 60 34 37 12 14 13 31 37 34 41 15 43 17 47 48 19 51 52 48 56 57 54 55 58 58 59 60 61 61 2 Compound Canonicalized 5 2012.11.26 1 Compound Complexity 7 E_COMPLEXITY 3.408 Cactvs xemistry.com 2012.11.26 1470 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.408 Cactvs xemistry.com 2012.11.26 11 Count Hydrogen Bond Donor 5 E_NHDONORS 3.408 Cactvs xemistry.com 2012.11.26 12 Count Rotatable Bond 5 E_NROTBONDS 3.408 Cactvs xemistry.com 2012.11.26 24 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.408 Cactvs xemistry.com 2012.11.26 00000371F07FFC000000000000000000000000000001600000003060C000000000005801F400001E00100800000C2CE19E063CCEF2C99200A80335F75C0082802031222008D9A1BE6C980A76FEC291B394700866F611D8D807BFC9E08EA0000000000200004000000000040000000000000000 IUPAC Name Allowed 1 2.2.0 LexiChem openeye.com 2012.11.26 [(5S)-5-azaniumyl-6-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-1-benzyl-2-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]amino]-6-oxo-hexyl]ammonium IUPAC Name CAS-like Style 1 2.2.0 LexiChem openeye.com 2012.11.26 [(2S)-6-ammonio-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]ammonium IUPAC Name Preferred 1 2.2.0 LexiChem openeye.com 2012.11.26 [(2S)-6-azaniumyl-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]azanium IUPAC Name Systematic 1 2.2.0 LexiChem openeye.com 2012.11.26 [(2S)-6-azaniumyl-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-3-(4-hydroxyphenyl)-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-3-phenyl-propan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanyl-1,4-bis(oxidanylidene)butan-2-yl]amino]-1-oxidanylidene-hexan-2-yl]azanium IUPAC Name Traditional 1 2.2.0 LexiChem openeye.com 2012.11.26 [(5S)-5-ammonio-6-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-1-benzyl-2-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-2-keto-ethyl]amino]-2-keto-1-methylol-ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-keto-ethyl]amino]-1-(carboxymethyl)-2-keto-ethyl]amino]-6-keto-hexyl]ammonium InChI Standard 1 1.0.4 InChI iupac.org 2012.11.26 InChI=1S/C42H52N8O11/c43-17-7-6-11-29(44)37(55)46-33(21-36(53)54)40(58)48-32(20-26-22-45-30-12-5-4-10-28(26)30)39(57)50-35(23-51)41(59)47-31(18-24-8-2-1-3-9-24)38(56)49-34(42(60)61)19-25-13-15-27(52)16-14-25/h1-5,8-10,12-16,22,29,31-35,45,51-52H,6-7,11,17-21,23,43-44H2,(H,46,55)(H,47,59)(H,48,58)(H,49,56)(H,50,57)(H,53,54)(H,60,61)/p+2/t29-,31-,32-,33-,34-,35-/m0/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.11.26 ORAWTQLGAVSURU-LXOXETEGSA-P Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 846.391205 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 C42H54N8O11+2 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 846.92516 SMILES Canonical 1 1.9.0 OEChem openeye.com 2012.11.26 C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=C(C=C2)O)C(=O)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC(=O)O)NC(=O)C(CCCC[NH3+])[NH3+] SMILES Isomeric 1 1.9.0 OEChem openeye.com 2012.11.26 C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCC[NH3+])[NH3+] Topological Polar Surface Area 7 E_TPSA 3.408 Cactvs xemistry.com 2012.11.26 332 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 846.391205 61 6 6 0 0 0 0 0 1 64