70679352 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 16 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 3 3 3 4 4 5 6 6 6 7 7 8 8 8 9 9 10 12 13 13 14 14 15 15 16 16 17 17 18 5 11 6 9 11 7 8 23 11 12 12 7 19 20 21 22 10 24 25 10 26 27 13 14 15 16 28 17 29 18 30 18 31 32 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 2 1 1 1 2 1 1 1 2 1 2 1 1 1 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 Conformer RMSD 7 2012.11.26 0.6 Diverse Conformer ID List 6 2012.11.26 1 11 5 9 8 4 7 10 2 6 3 Charge MMFF94 Partial 2 1.9.0 OEChem openeye.com 2012.11.26 26 1 0.18 10 -0.29 11 0.46 12 0.46 13 0.05 14 -0.15 15 -0.15 16 -0.15 17 -0.15 18 -0.15 2 -0.55 23 0.36 26 0.15 27 0.15 28 0.15 29 0.15 3 -0.9 30 0.15 31 0.15 32 0.15 4 -0.57 5 -0.51 6 0.37 7 0.27 8 0.41 9 -0.05 Count Effective Rotor 7 1.9.0 OEChem ncbi.nlm.nih.gov 2012.11.26 3 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.3 OEShape openeye.com 2012.11.26 7 1 3 cation 1 3 donor 3 2 4 11 cation 3 4 5 12 cation 5 1 4 5 11 12 rings 6 13 14 15 16 17 18 rings 7 2 3 6 7 8 9 10 rings 18 0 0 0 0 0 0 0 1 1