70674387 -OEChem-05092403462D 95 95 0 0 0 0 0 0 0999 V2000 8.9045 2.5000 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.9045 5.0000 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.9045 0.0000 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.0739 13.1200 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 10.0021 19.1200 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 14.1200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.4040 15.6200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 9.1360 8.6200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.8059 10.1200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.5369 9.6200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 18.2721 9.6200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 12.6002 11.6200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 10.0021 10.1200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 14.3322 12.6200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8059 14.1200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 17.1200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 10.1200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4040 8.6200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.6720 15.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1720 16.4860 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6720 15.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7341 11.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6720 14.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 16.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7341 10.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8681 11.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6002 12.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4662 11.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8681 9.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0021 11.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4662 13.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.3322 11.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1360 9.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.1982 13.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8059 13.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4040 17.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9399 12.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6720 12.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4040 18.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 17.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4040 9.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9399 11.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6720 11.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 19.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1360 17.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8059 11.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1360 18.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 10.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6720 9.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6720 8.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 8.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6469 16.8846 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6970 16.8846 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0893 15.8321 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5643 15.0094 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2711 10.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9462 9.5374 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3447 10.2277 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2666 12.0949 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4696 12.0949 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3881 13.2026 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9896 12.5123 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0676 10.6451 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.8647 10.6451 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4696 9.1450 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2666 9.1450 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7900 11.7026 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3915 11.0123 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.8647 13.5949 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0676 13.5949 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.5443 11.0374 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9428 11.7277 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2690 14.4300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0010 17.4300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 15.5082 12.5831 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 15.7352 13.4300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8882 13.6569 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 10.7400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2089 12.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8671 18.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 16.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4030 11.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2089 11.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 19.7400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6730 17.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 10.7400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1350 8.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 7.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0739 9.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 18.8090 9.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 17.7352 9.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9045 2.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9045 5.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9045 0.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 93 1 0 0 0 0 2 94 1 0 0 0 0 3 95 1 0 0 0 0 4 37 1 0 0 0 0 5 47 1 0 0 0 0 6 23 2 0 0 0 0 7 24 2 0 0 0 0 8 33 2 0 0 0 0 9 46 1 0 0 0 0 9 49 1 0 0 0 0 10 89 1 0 0 0 0 10 90 1 0 0 0 0 11 91 1 0 0 0 0 11 92 1 0 0 0 0 12 22 1 0 0 0 0 12 27 1 0 0 0 0 12 28 1 0 0 0 0 13 29 1 0 0 0 0 13 30 1 0 0 0 0 13 33 1 0 0 0 0 14 31 1 0 0 0 0 14 32 1 0 0 0 0 14 34 1 0 0 0 0 15 23 1 0 0 0 0 15 35 1 0 0 0 0 15 73 1 0 0 0 0 16 24 1 0 0 0 0 16 36 1 0 0 0 0 16 74 1 0 0 0 0 17 33 1 0 0 0 0 17 41 1 0 0 0 0 17 78 1 0 0 0 0 18 41 2 0 0 0 0 18 51 1 0 0 0 0 19 20 1 0 0 0 0 19 21 1 0 0 0 0 19 23 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 20 52 1 0 0 0 0 20 53 1 0 0 0 0 21 54 1 0 0 0 0 21 55 1 0 0 0 0 22 25 1 0 0 0 0 22 26 1 0 0 0 0 22 56 1 0 0 0 0 25 29 1 0 0 0 0 25 57 1 0 0 0 0 25 58 1 0 0 0 0 26 30 1 0 0 0 0 26 59 1 0 0 0 0 26 60 1 0 0 0 0 27 31 1 0 0 0 0 27 61 1 0 0 0 0 27 62 1 0 0 0 0 28 32 1 0 0 0 0 28 63 1 0 0 0 0 28 64 1 0 0 0 0 29 65 1 0 0 0 0 29 66 1 0 0 0 0 30 67 1 0 0 0 0 30 68 1 0 0 0 0 31 69 1 0 0 0 0 31 70 1 0 0 0 0 32 71 1 0 0 0 0 32 72 1 0 0 0 0 34 75 1 0 0 0 0 34 76 1 0 0 0 0 34 77 1 0 0 0 0 35 37 2 0 0 0 0 35 38 1 0 0 0 0 36 39 2 0 0 0 0 36 40 1 0 0 0 0 37 42 1 0 0 0 0 38 43 2 0 0 0 0 38 79 1 0 0 0 0 39 44 1 0 0 0 0 39 80 1 0 0 0 0 40 45 2 0 0 0 0 40 81 1 0 0 0 0 41 48 1 0 0 0 0 42 46 2 0 0 0 0 42 82 1 0 0 0 0 43 46 1 0 0 0 0 43 83 1 0 0 0 0 44 47 2 0 0 0 0 44 84 1 0 0 0 0 45 47 1 0 0 0 0 45 85 1 0 0 0 0 48 49 2 0 0 0 0 48 86 1 0 0 0 0 49 50 1 0 0 0 0 50 51 2 0 0 0 0 50 87 1 0 0 0 0 51 88 1 0 0 0 0 M END > 70674387 > 1 > 1060 > 11 > 8 > 8 > AAADcfB/uYAGAAAAAAAAAAAAGAAAAAAAAAA8eLECAAAAAAAB0AAAHwAQCAAADizBkgw/9pPIFACoADd3dACCiCkxIiAJ2CE+bJiMZnrM8ZuWOCju1xvI6CewQAAIAEAAAAAAAAAAgAAAAAAAAAAAAAAAAA== > N1'-[2-fluoro-4-[[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]-4-pyridyl]oxy]phenyl]-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;dihydrate;trihydrochloride > N1'-[2-fluoro-4-[[2-[[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]-oxomethyl]amino]-4-pyridinyl]oxy]phenyl]-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;dihydrate;trihydrochloride > 1-N'-[2-fluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;dihydrate;trihydrochloride > 1-N'-[2-fluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;dihydrate;trihydrochloride > N1'-[2-fluoranyl-4-[2-[[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonylamino]pyridin-4-yl]oxy-phenyl]-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;dihydrate;trihydrochloride > N'-[2-fluoro-4-[[2-[[4-(4-methylpiperazino)piperidine-1-carbonyl]amino]-4-pyridyl]oxy]phenyl]-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;dihydrate;trihydrochloride > InChI=1S/C33H37F2N7O4.3ClH.2H2O/c1-40-16-18-41(19-17-40)24-9-14-42(15-10-24)32(45)39-29-21-26(8-13-36-29)46-25-6-7-28(27(35)20-25)38-31(44)33(11-12-33)30(43)37-23-4-2-22(34)3-5-23;;;;;/h2-8,13,20-21,24H,9-12,14-19H2,1H3,(H,37,43)(H,38,44)(H,36,39,45);3*1H;2*1H2 > BZVXCWCIEKXIJJ-UHFFFAOYSA-N > 777.238672 > C33H44Cl3F2N7O6 > 779.1 > CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F.O.O.Cl.Cl.Cl > CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F.O.O.Cl.Cl.Cl > 121 > 777.238672 > 0 > 51 > 0 > 0 > 0 > 0 > 0 > 6 > -1 > 1 5 255 > 18 41 8 18 51 8 35 37 8 35 38 8 36 39 8 36 40 8 37 42 8 38 43 8 39 44 8 40 45 8 41 48 8 42 46 8 43 46 8 44 47 8 45 47 8 48 49 8 49 50 8 50 51 8 $$$$