70661819 -OEChem-05102419152D 70 74 0 1 0 0 0 0 0999 V2000 6.9009 1.7320 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 6.5348 0.3660 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 7.9009 0.0000 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 5.7387 8.6457 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 9.1329 0.8660 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.2669 2.3660 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.1509 9.4547 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.6586 4.9411 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6308 5.1486 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 14.8003 7.6266 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 4.1509 7.8367 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 4.8940 7.1675 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 3.9430 6.8585 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1998 8.1457 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7387 8.6457 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8722 6.9596 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1998 9.1457 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3059 7.6110 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1812 6.0086 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5413 7.7028 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3059 9.6804 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3998 8.1249 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1594 5.8007 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3998 9.1665 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5195 7.4949 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8285 6.5438 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5357 7.6215 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7356 6.1371 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6025 6.6356 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4676 6.1341 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3345 6.6326 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3362 7.6326 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1997 6.1311 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0683 7.6296 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2031 8.1311 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0666 6.6296 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.9352 8.1281 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.6672 8.1251 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.7986 6.6266 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4009 0.8660 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2669 1.3660 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9265 6.5484 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3234 6.8802 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0293 6.2446 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3425 10.0444 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3131 6.9911 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7663 5.5478 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3497 8.2924 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3131 10.3003 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8641 9.4786 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9343 7.9556 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2237 8.1573 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.3095 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8478 7.0858 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4074 4.3742 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6035 7.2556 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4665 5.5141 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7998 7.9436 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1986 5.5111 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2042 8.7511 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6029 6.3187 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3345 8.6024 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5375 8.6038 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 15.9763 7.5877 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 16.2047 8.4342 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 15.3581 8.6626 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1786 6.6277 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.7975 6.0066 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 15.4186 6.6256 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6698 1.1760 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 40 1 0 0 0 0 2 40 1 0 0 0 0 3 40 1 0 0 0 0 4 15 2 0 0 0 0 5 41 1 0 0 0 0 5 70 1 0 0 0 0 6 41 2 0 0 0 0 7 15 1 0 0 0 0 7 17 1 0 0 0 0 7 45 1 0 0 0 0 8 9 1 0 0 0 0 8 23 1 0 0 0 0 8 55 1 0 0 0 0 9 28 2 0 0 0 0 10 37 1 0 0 0 0 10 38 1 0 0 0 0 10 39 1 0 0 0 0 11 12 1 0 0 0 0 11 13 1 1 0 0 0 11 14 1 0 0 0 0 11 15 1 0 0 0 0 12 13 1 0 0 0 0 12 16 1 6 0 0 0 12 42 1 0 0 0 0 13 43 1 0 0 0 0 13 44 1 0 0 0 0 14 17 2 0 0 0 0 14 18 1 0 0 0 0 16 19 2 0 0 0 0 16 20 1 0 0 0 0 17 21 1 0 0 0 0 18 22 2 0 0 0 0 18 46 1 0 0 0 0 19 23 1 0 0 0 0 19 47 1 0 0 0 0 20 25 2 0 0 0 0 20 48 1 0 0 0 0 21 24 2 0 0 0 0 21 49 1 0 0 0 0 22 24 1 0 0 0 0 22 27 1 0 0 0 0 23 26 2 0 0 0 0 24 50 1 0 0 0 0 25 26 1 0 0 0 0 25 51 1 0 0 0 0 26 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 27 54 1 0 0 0 0 28 29 1 0 0 0 0 29 30 2 0 0 0 0 29 56 1 0 0 0 0 30 31 1 0 0 0 0 30 57 1 0 0 0 0 31 32 2 0 0 0 0 31 33 1 0 0 0 0 32 35 1 0 0 0 0 32 58 1 0 0 0 0 33 36 2 0 0 0 0 33 59 1 0 0 0 0 34 35 2 0 0 0 0 34 36 1 0 0 0 0 34 37 1 0 0 0 0 35 60 1 0 0 0 0 36 61 1 0 0 0 0 37 62 1 0 0 0 0 37 63 1 0 0 0 0 38 64 1 0 0 0 0 38 65 1 0 0 0 0 38 66 1 0 0 0 0 39 67 1 0 0 0 0 39 68 1 0 0 0 0 39 69 1 0 0 0 0 40 41 1 0 0 0 0 M END > 70661819 > 1 > 872 > 8 > 3 > 5 > AAADceB7sYAAAAAAAAAAAAAAGAAAAWLAAAAwYMAAAAAAAFgB9AAAHwAYCAAADwjBnhQyyPPjAgCqAyXyWACSBAAhAgAYuSE4ZJgIILLA1dGEpAhgnADIyAcciMCPyAACQAACAACQAASAAAQAAAAAAAAAAA== > (1R,2S)-2-[3-[(E)-2-[4-[(dimethylamino)methyl]phenyl]vinyl]-1H-indazol-6-yl]-5'-methyl-spiro[cyclopropane-1,3'-indoline]-2'-one;2,2,2-trifluoroacetic acid > (2'S,3R)-2'-[3-[(E)-2-[4-[(dimethylamino)methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5-methyl-2-spiro[1H-indole-3,1'-cyclopropane]one;2,2,2-trifluoroacetic acid > (2'S,3R)-2'-[3-[(E)-2-[4-[(dimethylamino)methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5-methylspiro[1H-indole-3,1'-cyclopropane]-2-one;2,2,2-trifluoroacetic acid > (2'S,3R)-2'-[3-[(E)-2-[4-[(dimethylamino)methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5-methylspiro[1H-indole-3,1'-cyclopropane]-2-one;2,2,2-trifluoroacetic acid > (2'S,3R)-2'-[3-[(E)-2-[4-[(dimethylamino)methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5-methyl-spiro[1H-indole-3,1'-cyclopropane]-2-one;2,2,2-tris(fluoranyl)ethanoic acid > (1R,2S)-2-[3-[(E)-2-[4-[(dimethylamino)methyl]phenyl]vinyl]-1H-indazol-6-yl]-5'-methyl-spiro[cyclopropane-1,3'-indoline]-2'-one;2,2,2-trifluoroacetic acid > InChI=1S/C29H28N4O.C2HF3O2/c1-18-4-12-26-23(14-18)29(28(34)30-26)16-24(29)21-10-11-22-25(31-32-27(22)15-21)13-9-19-5-7-20(8-6-19)17-33(2)3;3-2(4,5)1(6)7/h4-15,24H,16-17H2,1-3H3,(H,30,34)(H,31,32);(H,6,7)/b13-9+;/t24-,29-;/m0./s1 > PZKVJNHIBAWZHA-RWBUBLOKSA-N > 562.21917529 > C31H29F3N4O3 > 562.6 > CC1=CC2=C(C=C1)NC(=O)C23CC3C4=CC5=C(C=C4)C(=NN5)C=CC6=CC=C(C=C6)CN(C)C.C(=O)(C(F)(F)F)O > CC1=CC2=C(C=C1)NC(=O)[C@@]23C[C@H]3C4=CC5=C(C=C4)C(=NN5)/C=C/C6=CC=C(C=C6)CN(C)C.C(=O)(C(F)(F)F)O > 98.3 > 562.21917529 > 0 > 41 > 2 > 0 > 1 > 0 > 0 > 2 > -1 > 1 5 255 > 11 13 5 12 16 6 14 17 8 14 18 8 16 19 8 16 20 8 17 21 8 18 22 8 19 23 8 20 25 8 21 24 8 22 24 8 23 26 8 25 26 8 26 28 8 31 32 8 31 33 8 32 35 8 33 36 8 34 35 8 34 36 8 8 23 8 8 9 8 9 28 8 $$$$