70423301 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 4 4 5 6 7 7 8 8 9 10 10 10 11 11 11 12 12 12 13 13 13 14 14 14 15 15 15 16 16 16 17 17 17 18 18 18 19 19 19 20 20 20 22 22 22 23 23 23 25 25 26 26 26 27 27 28 28 30 31 32 32 33 33 34 34 35 35 35 37 37 38 38 39 39 40 41 42 42 42 43 43 44 44 47 47 48 48 48 49 49 50 50 51 51 52 52 53 53 54 55 55 56 56 57 57 58 58 59 21 24 29 36 48 36 40 45 98 46 101 46 16 24 66 21 22 72 19 36 77 30 31 79 29 35 40 28 86 87 17 21 60 18 61 62 23 63 64 20 24 65 25 67 68 26 29 69 28 70 71 27 31 32 73 74 30 33 75 76 34 78 37 38 39 80 41 81 46 82 83 43 84 44 85 41 88 42 89 47 90 91 45 92 45 93 49 50 51 94 95 52 96 53 97 55 56 54 99 54 100 102 57 103 58 104 59 105 59 106 107 2 2 2 1 1 2 2 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 2 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 2 1 1 1 2 1 1 1 1 1 1 2 1 2 1 2 1 1 1 1 1 1 2 1 2 1 1 1 1 16 10 17 21 60 1 1 19 12 20 24 65 1 1 22 11 26 29 69 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 5.6352 8.6173 5.8994 9.6423 9.2851 7.1885 2.6067 9.5027 9.8599 6.9709 6.9244 7.9959 6.0389 7.5457 11.5528 7.2816 8.2601 8.9279 7.3281 6.3496 6.6137 6.2566 9.9064 7.6388 6.0389 5.278 5.0927 10.5743 6.5672 5.0927 6.6225 4.6102 4.2267 4.2267 8.2136 8.9744 4.9209 3.6317 3.3607 7.8564 3.3607 8.8349 4.253 2.9639 3.2745 9.1921 9.1456 10.6208 8.4777 10.1241 11.2886 8.7884 10.4347 9.7669 12.2671 10.978 12.935 11.6458 12.6243 7.6956 8.7864 8.0288 8.4016 9.1592 7.1355 6.3642 6.329 5.7358 6.8632 10.4328 9.6752 7.5311 4.7517 5.5093 10.0479 10.8055 7.8033 7.2425 6.2315 4.2267 4.2267 7.6872 8.4448 5.5275 3.4391 11.9668 11.7454 2.8237 2.8237 8.8555 9.4487 4.4456 2.3572 11.1472 10.3895 7.871 10.5381 2 8.3743 11.0414 10.1094 9.9595 12.4598 10.3713 13.5417 11.4532 13.0384 -0.1837 -2.2104 3.4122 -4.6495 -2.9547 4.5689 4.4883 3.2865 1.5917 -1.6723 0.9731 -4.1114 -6.1333 2.8741 -1.5917 -0.7218 -0.5155 -1.2598 -3.3671 -3.5733 0.0225 1.7174 -1.0536 -2.4166 -4.5239 1.5111 -4.8286 -1.7979 2.6679 -5.8286 -5.3286 2.2554 -4.3286 -6.3286 2.1298 -3.9052 3.206 2.0492 -4.8286 3.8246 -5.8286 4.0308 3.9503 2.7935 3.744 2.336 4.9814 -4.4433 5.7257 5.1876 -5.1876 6.6762 6.1381 6.8824 -4.9814 -6.1381 -5.7257 -6.8824 -6.6762 -1.1832 -0.1879 0.0597 -1.5875 -1.8351 -3.9564 -1.8001 -2.9537 -3.486 1.8452 -0.726 -0.4784 1.1009 1.1835 0.9359 -2.1256 -2.3732 -4.7007 -5.3286 -6.7226 -3.7086 -6.9486 1.8022 1.5545 3.3338 1.4599 -2.0532 -1.0024 -4.5186 -6.1386 3.4112 3.9435 4.5396 2.6657 -4.1156 -3.868 5.5978 4.7261 4.3605 7.1376 6.266 3.4144 7.4717 -4.392 -6.266 -5.5978 -7.4717 -7.1376 8 8 6 5 5 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 13 13 16 19 22 25 25 27 27 30 32 32 33 34 37 38 39 43 44 47 47 49 50 51 51 52 53 55 56 57 58 30 31 10 12 11 27 31 30 33 34 37 38 39 41 43 44 41 45 45 49 50 52 53 55 56 54 54 57 58 59 59 0 Compound Canonicalized 5 2012.11.26 1 Compound Complexity 7 E_COMPLEXITY 3.408 Cactvs xemistry.com 2012.11.26 1380 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.408 Cactvs xemistry.com 2012.11.26 10 Count Hydrogen Bond Donor 5 E_NHDONORS 3.408 Cactvs xemistry.com 2012.11.26 7 Count Rotatable Bond 5 E_NROTBONDS 3.408 Cactvs xemistry.com 2012.11.26 21 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.408 Cactvs xemistry.com 2012.11.26 00000371F07FBC000000000000000000000000000001600000003060C180000000005801F400001E00100800000C2CE19E063CCEF3C99600A80335F75C0082802031222008D9A1BE6C990A66F2C2B5BB9C700864D631D8F80798C9E08EA0000000000200004000000000040000000000000000 IUPAC Name Allowed 1 2.2.0 LexiChem openeye.com 2012.11.26 2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-(2-phenylacetyl)amino]acetic acid IUPAC Name CAS-like Style 1 2.2.0 LexiChem openeye.com 2012.11.26 2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-3-(1H-indol-3-yl)-1-oxo-2-(phenylmethoxycarbonylamino)propyl]amino]-1-oxohexyl]amino]-3-(4-hydroxyphenyl)-1-oxopropyl]-(1-oxo-2-phenylethyl)amino]acetic acid IUPAC Name Preferred 1 2.2.0 LexiChem openeye.com 2012.11.26 2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-(2-phenylacetyl)amino]acetic acid IUPAC Name Systematic 1 2.2.0 LexiChem openeye.com 2012.11.26 2-[[(2S)-2-[[(2S)-6-azanyl-2-[[(2S)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-(2-phenylethanoyl)amino]ethanoic acid IUPAC Name Traditional 1 2.2.0 LexiChem openeye.com 2012.11.26 2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-(2-phenylacetyl)amino]acetic acid InChI Standard 1 1.0.4 InChI iupac.org 2012.11.26 InChI=1S/C44H48N6O9/c45-22-10-9-17-36(47-42(56)37(25-32-26-46-35-16-8-7-15-34(32)35)49-44(58)59-28-31-13-5-2-6-14-31)41(55)48-38(23-30-18-20-33(51)21-19-30)43(57)50(27-40(53)54)39(52)24-29-11-3-1-4-12-29/h1-8,11-16,18-21,26,36-38,46,51H,9-10,17,22-25,27-28,45H2,(H,47,56)(H,48,55)(H,49,58)(H,53,54)/t36-,37-,38-/m0/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.11.26 YWJKOKOZYUJUEY-QXUSSCGESA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.11.26 2.3 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 804.348277 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 C44H48N6O9 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 804.88672 SMILES Canonical 1 1.9.0 OEChem openeye.com 2012.11.26 C1=CC=C(C=C1)CC(=O)N(CC(=O)O)C(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CCCCN)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)OCC5=CC=CC=C5 SMILES Isomeric 1 1.9.0 OEChem openeye.com 2012.11.26 C1=CC=C(C=C1)CC(=O)N(CC(=O)O)C(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)OCC5=CC=CC=C5 Topological Polar Surface Area 7 E_TPSA 3.408 Cactvs xemistry.com 2012.11.26 233 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 804.348277 59 3 3 0 0 0 0 0 1 16