69756297 -OEChem-03292408222D 63 66 0 1 0 0 0 0 0999 V2000 11.5078 -3.5272 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.7875 -2.5072 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 0.5272 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 -0.9728 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -0.9728 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 2.5272 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 0.5272 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.8222 2.5619 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.8106 -0.5074 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 10.7282 1.0064 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 1.0272 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0 5.4641 2.0272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 2.5272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 2.0272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 1.0272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -0.4728 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 -0.4728 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 1.0272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 0.0272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3660 -1.3388 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3660 0.3932 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 0.5272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 2.0272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 1.0272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 2.5272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 2.0272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8222 0.4926 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7282 2.0480 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 3.5272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6708 -1.0174 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6592 -2.0173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5425 -0.5274 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5194 -2.5273 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4027 -1.0374 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3911 -2.0373 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0010 1.3372 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0747 1.9196 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6762 2.6098 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9966 3.0022 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1996 3.0022 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5200 2.6098 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1215 1.9196 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1215 1.1349 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5200 0.4446 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3100 0.5641 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4631 0.3372 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6900 -0.5097 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8291 -1.0288 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0560 -1.8758 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9030 -1.6488 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9030 0.0832 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6760 0.9302 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8291 0.7032 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 -0.0928 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 3.1472 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2701 -0.8112 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2639 2.3601 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9501 3.5272 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 4.1472 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7101 3.5272 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5497 0.0925 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.9432 -0.7336 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.9245 -2.3535 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 33 1 0 0 0 0 2 31 1 0 0 0 0 3 11 1 0 0 0 0 3 18 1 0 0 0 0 4 16 1 0 0 0 0 4 17 1 0 0 0 0 5 16 2 0 0 0 0 6 23 1 0 0 0 0 6 29 1 0 0 0 0 7 11 1 0 0 0 0 7 15 1 0 0 0 0 7 16 1 0 0 0 0 8 26 1 0 0 0 0 8 28 2 0 0 0 0 9 27 1 0 0 0 0 9 30 1 0 0 0 0 9 56 1 0 0 0 0 10 27 2 0 0 0 0 10 28 1 0 0 0 0 11 12 1 0 0 0 0 11 36 1 0 0 0 0 12 13 1 0 0 0 0 12 37 1 0 0 0 0 12 38 1 0 0 0 0 13 14 1 0 0 0 0 13 39 1 0 0 0 0 13 40 1 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 14 42 1 0 0 0 0 15 43 1 0 0 0 0 15 44 1 0 0 0 0 17 19 1 0 0 0 0 17 20 1 0 0 0 0 17 21 1 0 0 0 0 18 22 1 0 0 0 0 18 23 2 0 0 0 0 19 45 1 0 0 0 0 19 46 1 0 0 0 0 19 47 1 0 0 0 0 20 48 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 21 51 1 0 0 0 0 21 52 1 0 0 0 0 21 53 1 0 0 0 0 22 24 2 0 0 0 0 22 54 1 0 0 0 0 23 25 1 0 0 0 0 24 26 1 0 0 0 0 24 27 1 0 0 0 0 25 26 2 0 0 0 0 25 55 1 0 0 0 0 28 57 1 0 0 0 0 29 58 1 0 0 0 0 29 59 1 0 0 0 0 29 60 1 0 0 0 0 30 31 2 0 0 0 0 30 32 1 0 0 0 0 31 33 1 0 0 0 0 32 34 2 0 0 0 0 32 61 1 0 0 0 0 33 35 2 0 0 0 0 34 35 1 0 0 0 0 34 62 1 0 0 0 0 35 63 1 0 0 0 0 M END > 69756297 > 1 > 713 > 8 > 1 > 7 > AAADceB7uQAEAAAAAAAAAAAAAAAAAAAAAAA8eIEAAAAAAACx9AAAHwIQAAAADE7hni43/vfIFACoAyZjfACCiCkxJ6AJ2CA+7piNLuLF+9uOPCru1hvK6Cew0BMOIEABAgICQABAgAIEBASAAAAAAAAAAA== > tert-butyl 2-[4-(3-chloro-2-fluoro-anilino)-7-methoxy-quinazolin-6-yl]oxypiperidine-1-carboxylate > 2-[[4-(3-chloro-2-fluoroanilino)-7-methoxy-6-quinazolinyl]oxy]-1-piperidinecarboxylic acid tert-butyl ester > tert-butyl 2-[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidine-1-carboxylate > tert-butyl 2-[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidine-1-carboxylate > tert-butyl 2-[4-[(3-chloranyl-2-fluoranyl-phenyl)amino]-7-methoxy-quinazolin-6-yl]oxypiperidine-1-carboxylate > 2-[4-(3-chloro-2-fluoro-anilino)-7-methoxy-quinazolin-6-yl]oxypiperidine-1-carboxylic acid tert-butyl ester > InChI=1S/C25H28ClFN4O4/c1-25(2,3)35-24(32)31-11-6-5-10-21(31)34-20-12-15-18(13-19(20)33-4)28-14-29-23(15)30-17-9-7-8-16(26)22(17)27/h7-9,12-14,21H,5-6,10-11H2,1-4H3,(H,28,29,30) > WEEOPWMIKBUXCD-UHFFFAOYSA-N > 6 > 502.1783112 > C25H28ClFN4O4 > 503.0 > CC(C)(C)OC(=O)N1CCCCC1OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC > CC(C)(C)OC(=O)N1CCCCC1OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC > 85.8 > 502.1783112 > 0 > 35 > 0 > 1 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 10 27 8 10 28 8 18 22 8 18 23 8 22 24 8 23 25 8 24 26 8 24 27 8 25 26 8 11 3 3 30 31 8 30 32 8 31 33 8 32 34 8 33 35 8 34 35 8 8 26 8 8 28 8 $$$$