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Compound Summary for: CID 6918178


Also known as: Ulobetasol propionate; HALOBETASOL PROPIONATE; BMY-30056; 66852-54-8; UNII-91A0K1TY3Z; Miracorten; Ulobetasol; Ultravate (TN); CGP-14458
Molecular Formula: C25H31ClF2O5   Molecular Weight: 484.960446   InChIKey: BDSYKGHYMJNPAB-LICBFIPMSA-N
Halobetasol propionate is thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. It is used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.   From: DrugBank
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