6917108 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 16 15 15 15 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 3 3 3 3 4 4 4 4 5 5 6 7 7 8 9 10 13 14 15 15 17 19 20 21 22 22 23 23 23 24 24 25 25 26 26 27 27 27 28 28 28 29 29 29 30 30 30 31 31 32 32 33 34 34 35 36 37 38 38 38 38 39 39 40 40 42 42 42 43 43 43 44 46 46 46 47 47 47 49 49 49 50 50 51 52 52 53 53 54 54 55 55 56 56 57 57 58 58 50 51 6 9 10 12 8 11 14 16 11 13 17 18 32 33 30 31 66 34 78 77 40 80 39 83 87 45 48 51 59 101 33 35 36 36 37 35 44 41 44 41 81 82 45 46 84 48 49 90 31 32 60 33 61 34 62 63 64 65 37 67 41 39 40 42 43 45 68 69 70 71 72 73 74 75 76 79 47 85 86 48 88 89 50 91 92 93 94 52 53 95 54 96 55 56 57 97 58 98 59 99 59 100 1 1 1 1 1 2 1 1 1 2 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 1 1 1 1 1 2 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 2 1 1 1 2 1 2 1 1 1 30 6 32 31 60 2 1 31 7 30 33 61 3 1 32 5 30 34 62 1 1 33 5 23 31 63 1 1 39 15 38 45 68 1 1 52 51 95 53 96 54 2 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 6.0986 19.3228 16.0725 14.7874 17.0759 19.4256 19.4219 16.3799 19.22 20.3175 15.7652 18.3281 13.8096 15.1209 10.8762 17.0241 14.997 14.5778 11.9097 9.3394 4.4504 2.6062 17.3516 17.3516 15.5394 14.6733 15.5394 10.2615 7.6912 18.6156 18.6139 17.6651 17.6623 17.3577 16.4054 17.9352 16.4054 12.5244 11.5467 13.5022 15.5394 12.734 12.3148 14.6733 11.2393 9.9541 8.9763 8.669 7.3838 6.406 5.1209 4.8135 3.8357 3.5283 4.1988 2.5506 3.8914 2.2432 2.9136 19.1675 18.5158 17.0529 17.0497 17.9718 17.3804 19.9887 18.5552 10.9404 14.1163 13.5249 13.3403 12.864 12.1278 11.7086 12.1849 12.9211 20.6811 19.7222 14.1364 14.991 15.0024 16.0763 10.27 9.8458 10.5682 9.9768 15.587 8.3622 8.9536 7.2755 7.9979 7.4065 5.7919 6.3833 5.2292 3.42 4.805 2.1349 4.307 1.637 2 5.4135 -3.7669 -2.9245 -1.7633 -5.8453 -4.7616 -6.9371 -3.8761 -2.7722 -3.6641 -1.9729 -3.8697 -1.5537 -3.2319 -0.9249 -2.6171 -0.7855 -2.7411 1.5107 3.8331 4.8811 10.5906 -7.6058 -9.2153 -7.4106 -8.9106 -10.4106 0.9783 3.3007 -5.348 -6.348 -5.0373 -6.6553 -4.0857 -7.9106 -8.4106 -8.9106 -0.3925 -0.1829 -0.6021 -9.4106 0.5853 -1.3703 -7.9106 0.7687 1.9299 2.1395 3.0911 4.2523 4.4619 5.6231 6.5746 6.7843 7.7358 8.4778 7.9454 9.4294 8.897 9.639 -5.6304 -6.9601 -4.9392 -6.7512 -4.0005 -3.4661 -6.6859 -8.4106 -0.053 -0.5169 0.0175 0.4553 1.1915 0.7152 -1.2403 -1.9765 -1.5002 -4.1663 -2.4086 -7.6006 -3.8381 -10.7206 -10.7206 -0.7949 0.5183 2.0151 2.5495 -0.595 2.0543 1.5199 2.8406 4.3375 4.8718 4.3766 3.8423 7.0347 6.3242 8.3479 7.4854 9.8894 9.027 10.7206 8 8 8 8 8 8 8 8 6 3 6 6 8 8 6 8 8 8 8 8 8 23 23 24 24 25 25 26 26 30 31 32 33 35 37 39 54 54 55 56 57 58 35 36 36 37 35 44 41 44 6 7 34 23 37 41 15 55 56 57 58 59 59 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 1620 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 23 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 10 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 22 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371F07BBE034000000000000000000000000001624000003C400000000000005801FC00001E04100820000E1CE5DF06B7F6BFCC1718A8432773748282802D3130B009D8A16E5CD88B7E3AC2D9529E74082FD613FB99A7F2F0020F20000000000000004000000000000000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 S-[2-[3-[[(2S)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] (E)-3-(4-hydroxyphenyl)prop-2-enethioate IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 (E)-3-(4-hydroxyphenyl)-2-propenethioic acid S-[2-[[3-[[(2S)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-2-oxolanyl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethyl-1-oxobutyl]amino]-1-oxopropyl]amino]ethyl] ester IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 S-[2-[3-[[(2S)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (E)-3-(4-hydroxyphenyl)prop-2-enethioate IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 S-[2-[3-[[(2S)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (E)-3-(4-hydroxyphenyl)prop-2-enethioate IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 (E)-3-(4-hydroxyphenyl)prop-2-enethioic acid S-[2-[3-[[(2S)-4-[[[(2R,3R,5R)-5-adenin-9-yl-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] ester InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C30H42N7O18P3S/c1-30(2,25(42)28(43)33-10-9-20(39)32-11-12-59-21(40)8-5-17-3-6-18(38)7-4-17)14-52-58(49,50)55-57(47,48)51-13-19-24(54-56(44,45)46)23(41)29(53-19)37-16-36-22-26(31)34-15-35-27(22)37/h3-8,15-16,19,23-25,29,38,41-42H,9-14H2,1-2H3,(H,32,39)(H,33,43)(H,47,48)(H,49,50)(H2,31,34,35)(H2,44,45,46)/b8-5+/t19-,23?,24+,25-,29-/m1/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 DMZOKBALNZWDKI-IOTZNISBSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 -3.9 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 913.151988 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C30H42N7O18P3S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 913.676866 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)C=CC4=CC=C(C=C4)O)O SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CC(C)(COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@@H](C([C@@H](O1)N2C=NC3=C2N=CN=C3N)O)OP(=O)(O)O)[C@@H](C(=O)NCCC(=O)NCCSC(=O)/C=C/C4=CC=C(C=C4)O)O Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 409 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 913.151988 59 5 4 1 1 1 0 0 1 48