6816 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 16 15 15 15 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 3 3 3 3 4 4 4 4 5 5 6 7 7 8 9 11 12 14 14 15 17 18 20 21 21 21 22 22 23 23 24 24 25 25 25 26 26 26 27 27 27 28 28 28 29 29 30 30 31 32 32 33 34 35 35 35 35 36 37 37 38 38 39 39 39 40 40 40 43 44 44 44 45 45 45 47 47 47 48 48 48 84 6 11 12 13 8 10 15 16 9 10 17 19 30 31 28 29 55 32 38 66 67 37 69 70 76 42 46 31 33 34 34 36 33 43 41 43 42 44 71 41 72 73 46 47 79 29 30 49 31 50 32 51 52 53 54 36 56 37 38 39 40 41 42 57 58 59 61 62 63 60 64 65 68 45 74 75 46 77 78 48 80 81 82 83 1 1 1 1 1 2 1 1 1 2 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1 2 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 28 6 29 30 49 1 1 29 7 31 28 50 2 1 30 5 28 32 51 1 1 31 5 21 29 52 1 1 37 14 35 42 57 3 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 2.6062 15.8304 12.5801 11.295 13.5835 15.9332 15.9294 12.8875 10.3172 12.2727 15.7276 16.8251 14.8357 7.3838 11.6285 13.5317 11.5046 8.4173 11.0854 5.847 13.8592 13.8592 12.0469 11.1809 6.7691 12.0469 4.1988 15.1232 15.1214 14.1726 14.1698 13.8653 12.913 14.4428 9.032 12.913 8.0542 10.0098 9.2416 8.8224 12.0469 7.7469 11.1809 6.4617 5.4839 5.1765 3.8914 2.9136 15.6751 15.0234 13.5604 14.6075 14.4794 13.888 16.4963 15.0628 8.2448 10.6239 10.0325 8.2162 9.8478 9.3716 8.6354 8.6924 9.4286 16.2298 17.1886 10.644 6.7776 11.4986 6.3534 11.51 12.5839 7.0758 6.4844 12.0945 4.8698 5.4612 3.7831 4.5055 3.9141 2.2995 2.8909 2 8.002 -1.1783 -0.3359 0.8253 -3.2567 -2.173 -4.3486 -1.2875 1.0349 0.6157 -0.1836 -1.0755 -1.2811 1.6637 -0.6433 -0.0286 1.8031 4.0992 -0.1525 6.4216 -5.0173 -6.6267 -4.822 -6.322 3.5669 -7.822 5.8892 -2.7594 -3.7594 -2.4487 -4.0667 -1.4971 -5.322 -5.822 2.1961 -6.322 2.4057 1.9865 3.1738 1.2183 -6.822 3.3573 -5.322 4.5185 4.7281 5.6796 6.8408 7.0504 -3.0418 -4.3716 -2.3507 -4.5059 -1.4119 -0.8775 -4.0974 -5.822 1.8157 2.0717 2.6061 1.3482 3.0439 3.7801 3.3038 0.6121 1.0883 0.18 -1.5777 -5.012 1.7936 -1.2495 3.1068 -8.132 -8.132 4.6037 5.138 1.9936 4.6428 4.1085 5.4292 6.9261 7.4604 6.9652 6.4309 8.132 8 8 8 8 8 8 8 8 5 5 6 6 8 8 3 21 21 22 22 23 23 24 24 28 29 30 31 33 36 37 33 34 34 36 33 43 41 43 6 7 32 21 36 41 14 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 1270 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 21 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 10 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 18 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371F07BBE034000000000000000000000000001624000002C000000000000005801F800001E04100820000E1CE5D70687F0BFCC1714A8410771748280802D1110A00150A168541083581A40C8401E44080F1602D30020F230020900000000000000000000000000000000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-2-oxolanyl]methoxy-hydroxyphosphoryl] [3-hydroxy-4-[[3-(2-mercaptoethylamino)-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] hydrogen phosphate IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 [[(2R,3S,4R,5R)-5-adenin-9-yl-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [3-hydroxy-4-keto-4-[[3-keto-3-(2-mercaptoethylamino)propyl]amino]-2,2-dimethyl-butyl] hydrogen phosphate InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35)/t11-,14-,15-,16?,20-/m1/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 RGJOEKWQDUBAIZ-DRCCLKDXSA-N Log P XLogP3 7 3.0 sioc-ccbg.ac.cn 2012.05.21 -5.8 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 767.115209 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C21H36N7O16P3S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 767.534126 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCS)O SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CC(C)(COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCS)O Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 348 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 767.115209 48 5 4 1 0 0 0 0 1 12