6764767 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 8 8 8 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 4 5 5 5 6 6 7 7 8 8 9 9 10 10 11 12 12 12 14 14 15 15 16 17 18 18 18 19 19 19 20 20 21 23 23 24 24 25 26 26 27 28 29 29 29 30 30 30 31 31 31 13 16 30 27 31 22 9 12 13 7 11 22 40 21 25 10 14 11 15 13 18 32 33 17 34 16 35 17 36 37 38 39 20 21 24 22 23 26 25 41 27 42 29 28 43 28 44 45 46 47 48 49 50 51 52 53 2 1 1 1 1 2 1 1 1 1 2 1 1 2 1 2 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 2 1 1 1 1 1 2 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 6 -1 7 11 10 13 3 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 -0.5887 -6.3746 3.5435 1.1076 -2.9226 -1.0961 0.1431 4.9794 -3.9413 -3.4209 -2.0009 -3.1251 -1.7004 -5.2884 -4.1943 -5.5556 -6.0974 -2.95 3.3678 2.5317 4.6108 1.1999 2.8853 3.0155 4.1209 5.4643 3.8884 5.1142 4.5683 -5.7727 4.4881 -4.1104 -2.373 -5.723 -3.7115 -7.1606 -1.9525 -3.684 -3.078 0.3082 2.2312 2.062 6.4302 5.8461 5.5637 4.6167 3.8756 -5.3537 -5.0352 -6.5665 4.0498 4.6625 5.419 0.4861 -0.2461 -3.5576 1.0332 0.0619 0.5973 0.7813 1.614 -0.0502 0.1339 0.3745 -0.0753 0.3216 -0.3034 0.0775 -0.1775 -0.366 -1.5234 0.088 1.1674 0.3618 0.9952 2.4557 -1.2311 2.6248 -0.7078 -2.2818 -2.0194 3.996 -0.0476 -4.5831 0.3065 0.534 -0.4549 0.2317 -0.5647 -1.8928 -2.1698 -1.6265 0.7643 3.2991 -1.461 -0.5274 -2.7835 3.9724 4.6412 4.4337 0.96 -0.8261 -0.1357 -5.5329 -4.6614 -4.4522 1.8915 -2.2654 -0.7766 -2.4976 2.0356 -0.9264 -0.4079 0.549 1.069 -0.2117 -0.0418 3.4574 1.4377 1.2496 -1.3517 -1.178 0.1091 3.8725 -0.3901 -0.6369 0.2182 -1.2732 -0.3083 -0.7221 0.283 0.4741 -0.4546 0.1442 0.6658 -3.5427 -0.4718 3.7418 3.9718 2.2308 -2.3079 0.2223 3.6111 3.3801 4.9544 0.5867 -0.5016 -1.1919 0.9426 0.3835 1.1213 -0.2172 1.3916 -3.6382 -3.7658 -4.2917 -0.795 0.6067 -1.0341 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 006738DF00000001 Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 120.6514 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 55.955 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 10319926 262 14979121245976675734 10951579 204 17169822285280811973 11059845 2 15765856901391524562 114674 6 18187933833464277298 11796584 16 16588024619600278984 12107183 9 17768543693759424121 12236239 1 17561366192350258228 12596602 18 17131826552096046226 12758862 65 18260819360116435578 13533116 47 18341898480538579922 1361 87 17750819661120743818 13636023 51 17676759981463554520 15183329 4 14923940146292040831 15250474 111 17846207886803462783 15510800 12 18041851593237548122 17809404 112 17749677384360371368 18681886 176 15410337779530375528 19315092 285 17774712048955489546 19377110 9 17275114937444918043 20511986 3 17775272876825515229 21223535 225 17969491607869237365 21781051 124 15213599909583590705 22061861 79 18187081754574745959 23559900 14 17168153359604930412 23569914 152 17326296980664688871 23572383 38 18040718107832079497 23845131 108 18052808441603996568 3298306 158 16877659046273094715 341906 21 15698010595563793904 4015057 19 18409727396154343025 404807 14 17693098461626493191 439807 62 17986660666931738007 4403749 210 17760645168110526200 44062 13 16515978059259462235 508706 21 17532100405469949707 5309563 4 18051976922929835030 6823239 73 16950861274959914888 86090 222 17896060779220974378 8988823 20 18412543223784037516 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 594.56 16.23 3.34 2.91 9.06 1.8 1.25 2.88 -3.94 -10.2 -0.15 6.9 0.64 2.31 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 1311.53 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 320.1 Conformer RMSD 7 2009.12.11 0.8 Diverse Conformer ID List 6 2012.02.08 1 7 8 3 5 6 2 4 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 37 1 -0.57 10 0.09 11 0.36 12 0.3 13 0.63 14 -0.15 15 -0.15 16 0.08 17 -0.15 2 -0.36 20 0.09 21 0.31 22 0.54 23 -0.15 24 -0.15 25 0.17 26 -0.15 27 0.08 28 -0.15 29 0.14 3 -0.36 30 0.28 31 0.28 34 0.15 35 0.15 36 0.15 4 -0.57 40 0.37 41 0.15 42 0.15 43 0.15 44 0.15 5 -0.48 6 -0.51 7 -0.37 8 -0.62 9 0.12 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 6.2 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 11 1 1 acceptor 1 2 acceptor 1 3 acceptor 1 4 acceptor 1 6 acceptor 1 7 donor 1 8 acceptor 5 5 9 10 11 13 rings 6 19 21 24 26 27 28 rings 6 8 19 20 21 23 25 rings 6 9 10 14 15 16 17 rings 31 0 0 0 1 0 1 0 1 4