67195306 -OEChem-03292409082D 70 73 0 1 0 0 0 0 0999 V2000 2.0000 0.5283 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 4.5283 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 2.7320 3.5283 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 4.7320 3.5283 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 13.2375 -1.7036 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.2295 -4.1135 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -0.9717 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.6603 -1.4717 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 8.9282 -1.4717 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 0.5283 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 10.7648 -2.4662 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 11.7429 -2.6741 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2429 -1.8081 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 11.5738 -1.0649 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0216 -3.1353 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 -0.9717 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 0.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 0.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 0.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 0.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 -0.9717 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 0.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 1.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 1.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9641 -0.3377 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9641 1.3944 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 1.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 2.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 2.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 0.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 2.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 2.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 3.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 1.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6603 1.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 3.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 2.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 3.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 3.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1860 -2.2440 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5513 -3.2638 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3093 -2.9263 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4651 -1.2293 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0754 -0.7005 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2638 -0.5280 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6931 -2.6095 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4468 -3.3676 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6019 -2.2051 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3312 0.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7688 -4.5283 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5252 -1.2817 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4272 -0.0277 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6541 -0.8746 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5010 -0.6477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5010 1.0844 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2741 1.9313 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4272 1.7044 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8162 1.5283 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 2.1483 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5762 1.5283 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1350 2.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 -0.0917 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5252 1.7183 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3312 3.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3503 0.9914 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1972 1.2183 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9703 2.0653 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3291 2.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5252 3.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 4.1483 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 34 1 0 0 0 0 2 39 1 0 0 0 0 3 39 1 0 0 0 0 4 39 1 0 0 0 0 13 5 1 1 0 0 0 5 48 1 0 0 0 0 6 15 1 0 0 0 0 6 50 1 0 0 0 0 7 22 2 0 0 0 0 8 11 1 0 0 0 0 8 14 1 0 0 0 0 8 16 1 0 0 0 0 9 16 2 0 0 0 0 9 21 1 0 0 0 0 10 20 1 0 0 0 0 10 22 1 0 0 0 0 10 27 1 0 0 0 0 11 12 1 0 0 0 0 11 15 1 6 0 0 0 11 40 1 0 0 0 0 12 13 1 0 0 0 0 12 41 1 0 0 0 0 12 42 1 0 0 0 0 13 14 1 0 0 0 0 13 43 1 0 0 0 0 14 44 1 0 0 0 0 14 45 1 0 0 0 0 15 46 1 0 0 0 0 15 47 1 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 49 1 0 0 0 0 18 20 1 0 0 0 0 18 23 1 0 0 0 0 19 22 1 0 0 0 0 19 24 1 0 0 0 0 19 25 1 0 0 0 0 19 26 1 0 0 0 0 20 21 2 0 0 0 0 21 51 1 0 0 0 0 23 28 1 0 0 0 0 23 31 2 0 0 0 0 24 29 2 0 0 0 0 24 30 1 0 0 0 0 25 52 1 0 0 0 0 25 53 1 0 0 0 0 25 54 1 0 0 0 0 26 55 1 0 0 0 0 26 56 1 0 0 0 0 26 57 1 0 0 0 0 27 58 1 0 0 0 0 27 59 1 0 0 0 0 27 60 1 0 0 0 0 28 33 2 0 0 0 0 28 35 1 0 0 0 0 29 32 1 0 0 0 0 29 61 1 0 0 0 0 30 34 2 0 0 0 0 30 62 1 0 0 0 0 31 36 1 0 0 0 0 31 63 1 0 0 0 0 32 37 2 0 0 0 0 32 39 1 0 0 0 0 33 38 1 0 0 0 0 33 64 1 0 0 0 0 34 37 1 0 0 0 0 35 65 1 0 0 0 0 35 66 1 0 0 0 0 35 67 1 0 0 0 0 36 38 2 0 0 0 0 36 69 1 0 0 0 0 37 68 1 0 0 0 0 38 70 1 0 0 0 0 M END > 67195306 > 1 > 843 > 9 > 2 > 6 > AAADceB7McAAAAAAAAAAAAAAAAAAAWAAAAA8YIAAAAAAAAAB0AAAHwAACAAADjzhmh4/8JMIEgCoAjd3dACCgCkxEiAJ2CE4dJiKcHLAnZGUYAhuhgLYyCfYmMKPgAACAAAQAAAAAAQAACAAAAAAAAAAAA== > 2-[3-fluoro-5-(trifluoromethyl)phenyl]-N-[6-[(2R,4S)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-4-(o-tolyl)-3-pyridyl]-N,2-dimethyl-propanamide > 2-[3-fluoro-5-(trifluoromethyl)phenyl]-N-[6-[(2R,4S)-4-hydroxy-2-(hydroxymethyl)-1-pyrrolidinyl]-4-(2-methylphenyl)-3-pyridinyl]-N,2-dimethylpropanamide > 2-[3-fluoro-5-(trifluoromethyl)phenyl]-N-[6-[(2R,4S)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-4-(2-methylphenyl)pyridin-3-yl]-N,2-dimethylpropanamide > 2-[3-fluoro-5-(trifluoromethyl)phenyl]-N-[6-[(2R,4S)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-4-(2-methylphenyl)pyridin-3-yl]-N,2-dimethylpropanamide > 2-[3-fluoranyl-5-(trifluoromethyl)phenyl]-N-[6-[(2R,4S)-2-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-yl]-4-(2-methylphenyl)pyridin-3-yl]-N,2-dimethyl-propanamide > 2-[3-fluoro-5-(trifluoromethyl)phenyl]-N-[6-[(2R,4S)-4-hydroxy-2-methylol-pyrrolidino]-4-(o-tolyl)-3-pyridyl]-N,2-dimethyl-propionamide > InChI=1S/C29H31F4N3O3/c1-17-7-5-6-8-23(17)24-13-26(36-15-22(38)12-21(36)16-37)34-14-25(24)35(4)27(39)28(2,3)18-9-19(29(31,32)33)11-20(30)10-18/h5-11,13-14,21-22,37-38H,12,15-16H2,1-4H3/t21-,22+/m1/s1 > QHFOTSKFNPHKBY-YADHBBJMSA-N > 5.1 > 545.23015451 > C29H31F4N3O3 > 545.6 > CC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)F)C(F)(F)F)N4CC(CC4CO)O > CC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)F)C(F)(F)F)N4C[C@H](C[C@@H]4CO)O > 76.9 > 545.23015451 > 0 > 39 > 2 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 11 15 6 16 17 8 17 18 8 18 20 8 20 21 8 23 28 8 23 31 8 24 29 8 24 30 8 28 33 8 29 32 8 30 34 8 31 36 8 32 37 8 33 38 8 34 37 8 36 38 8 13 5 5 9 16 8 9 21 8 $$$$