67193673 -OEChem-04252421252D 67 70 0 1 0 0 0 0 0999 V2000 2.0000 0.5283 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 3.5283 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 4.5283 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 13.2375 -1.7036 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.2295 -4.1135 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -0.9717 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.6603 -1.4717 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 8.9282 -1.4717 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 0.5283 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 10.7648 -2.4662 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0 11.7429 -2.6741 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2429 -1.8081 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0 11.5738 -1.0649 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0216 -3.1353 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 -0.9717 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 0.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 0.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 0.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 0.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 -0.9717 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 0.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 1.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 1.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9641 -0.3377 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9641 1.3944 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 1.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 2.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 2.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 2.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 0.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 3.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6603 1.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 3.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 1.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 2.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 3.5283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 2.0283 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1860 -2.2440 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5513 -3.2638 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3093 -2.9263 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4651 -1.2293 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0754 -0.7005 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2638 -0.5280 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6931 -2.6095 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4468 -3.3676 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6019 -2.2051 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3312 0.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7688 -4.5283 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5252 -1.2817 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4272 -0.0277 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6541 -0.8746 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5010 -0.6477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5010 1.0844 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2741 1.9313 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4272 1.7044 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8162 1.5283 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 2.1483 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5762 1.5283 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5252 1.7183 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1350 2.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 -0.0917 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3312 3.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3503 0.9914 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1972 1.2183 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9703 2.0653 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5252 3.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3291 2.3383 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 34 1 0 0 0 0 2 35 1 0 0 0 0 3 36 1 0 0 0 0 4 12 1 0 0 0 0 4 46 1 0 0 0 0 5 14 1 0 0 0 0 5 48 1 0 0 0 0 6 21 2 0 0 0 0 7 10 1 0 0 0 0 7 13 1 0 0 0 0 7 15 1 0 0 0 0 8 15 2 0 0 0 0 8 20 1 0 0 0 0 9 18 1 0 0 0 0 9 21 1 0 0 0 0 9 26 1 0 0 0 0 10 11 1 0 0 0 0 10 14 1 0 0 0 0 10 38 1 0 0 0 0 11 12 1 0 0 0 0 11 39 1 0 0 0 0 11 40 1 0 0 0 0 12 13 1 0 0 0 0 12 41 1 0 0 0 0 13 42 1 0 0 0 0 13 43 1 0 0 0 0 14 44 1 0 0 0 0 14 45 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 47 1 0 0 0 0 17 18 1 0 0 0 0 17 22 1 0 0 0 0 18 20 2 0 0 0 0 19 21 1 0 0 0 0 19 23 1 0 0 0 0 19 24 1 0 0 0 0 19 25 1 0 0 0 0 20 49 1 0 0 0 0 22 27 2 0 0 0 0 22 28 1 0 0 0 0 23 29 2 0 0 0 0 23 30 1 0 0 0 0 24 50 1 0 0 0 0 24 51 1 0 0 0 0 24 52 1 0 0 0 0 25 53 1 0 0 0 0 25 54 1 0 0 0 0 25 55 1 0 0 0 0 26 56 1 0 0 0 0 26 57 1 0 0 0 0 26 58 1 0 0 0 0 27 31 1 0 0 0 0 27 32 1 0 0 0 0 28 33 2 0 0 0 0 28 59 1 0 0 0 0 29 35 1 0 0 0 0 29 60 1 0 0 0 0 30 34 2 0 0 0 0 30 61 1 0 0 0 0 31 36 2 0 0 0 0 31 62 1 0 0 0 0 32 63 1 0 0 0 0 32 64 1 0 0 0 0 32 65 1 0 0 0 0 33 36 1 0 0 0 0 33 66 1 0 0 0 0 34 37 1 0 0 0 0 35 37 2 0 0 0 0 37 67 1 0 0 0 0 M END > 67193673 > 1 > 779 > 8 > 2 > 6 > AAADceB7MYAAAAAAAAAAAAAAAAAAAWAAAAA8YIAAAAAAAAAB0AAAHwAACAAADjzhmg4/8JMIEgCoAjd3dACCgCkxEiAJ2CE4dJiKcHLAnZGUYAhuhgLYyCfYmMKPgAAAAAAQAAAAAAAAACAAAAAAAAAAAA== > 2-(3,5-difluorophenyl)-N-[4-(4-fluoro-2-methyl-phenyl)-6-[4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-3-pyridyl]-N,2-dimethyl-propanamide > 2-(3,5-difluorophenyl)-N-[4-(4-fluoro-2-methylphenyl)-6-[4-hydroxy-2-(hydroxymethyl)-1-pyrrolidinyl]-3-pyridinyl]-N,2-dimethylpropanamide > 2-(3,5-difluorophenyl)-N-[4-(4-fluoro-2-methylphenyl)-6-[4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamide > 2-(3,5-difluorophenyl)-N-[4-(4-fluoro-2-methylphenyl)-6-[4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamide > 2-[3,5-bis(fluoranyl)phenyl]-N-[4-(4-fluoranyl-2-methyl-phenyl)-6-[2-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-yl]pyridin-3-yl]-N,2-dimethyl-propanamide > 2-(3,5-difluorophenyl)-N-[4-(4-fluoro-2-methyl-phenyl)-6-(4-hydroxy-2-methylol-pyrrolidino)-3-pyridyl]-N,2-dimethyl-propionamide > InChI=1S/C28H30F3N3O3/c1-16-7-18(29)5-6-23(16)24-12-26(34-14-22(36)11-21(34)15-35)32-13-25(24)33(4)27(37)28(2,3)17-8-19(30)10-20(31)9-17/h5-10,12-13,21-22,35-36H,11,14-15H2,1-4H3 > DPLCKCPXBLJSAF-UHFFFAOYSA-N > 4.4 > 513.22392631 > C28H30F3N3O3 > 513.6 > CC1=C(C=CC(=C1)F)C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)F)F)N4CC(CC4CO)O > CC1=C(C=CC(=C1)F)C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)F)F)N4CC(CC4CO)O > 76.9 > 513.22392631 > 0 > 37 > 0 > 2 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 10 14 3 15 16 8 16 17 8 17 18 8 18 20 8 22 27 8 22 28 8 23 29 8 23 30 8 27 31 8 28 33 8 29 35 8 30 34 8 31 36 8 33 36 8 34 37 8 35 37 8 12 4 3 8 15 8 8 20 8 $$$$