mevastatin - PubChem

mevastatin - Compound Summary (CID 64715) Also known as: compactin, ML-236B, Mevastatinum [INN-Latin], Antibiotic ML 236B, Compactin (penicillium), CS 500, Mevastatine [INN-French] Molecular Formula: C₂₃H₃₄O₅ Molecular Weight: 390.51306 InChIKey: AJLFOPYRIVGYMJ-INTXDZFKSA-N Isolated as an antifungal metabolite from the fungus Penicillium brevicompactum, this is a potent HMG-CoA reductase inhibitor. This enzyme is the rate-limiting enzyme in cholesterol biosynthesis. This drug was never developped for therapeutics as it was found to have multiple side-effects. It is, however, used as the source for the widely used pravastatin. [Pubchem] From: DrugBank View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
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