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Compound Summary for: CID 6451164


Also known as: TMC278; 500287-72-9; Edurant; TMC 278; TMC-278; UNII-FI96A8X663; CHEBI:68606; R278474; KE-0036
Molecular Formula: C22H18N6   Molecular Weight: 366.41852   InChIKey: YIBOMRUWOWDFLG-ONEGZZNKSA-N
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine, a class of molecules that resemble pyrimidine nucleotides found in DNA. Because of its flexible chemical structure, resistance of rilpivirine is less likely to develop than other NNRTI's. FDA approved on May 20, 2011.    From: DrugBank
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