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Compound Summary for: CID 6450546

Gavestinel

Also known as: GV 150526A, GV 150526X, 153436-22-7, 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-((1E)-3-oxo-3-(phenylamino)-1-propenyl)-
Molecular Formula: C18H12Cl2N2O3   Molecular Weight: 375.20548   InChIKey: WZBNEZWCNKUOSM-VOTSOKGWSA-N
Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM). Gavestinel displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites and is orally bioavailable and active in vivo.    From: DrugBank
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