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Compound Summary for: CID 644241


Also known as: 641571-10-0; Tasigna; AMN107; AMN 107; AMN-107; CHEBI:52172; UNII-F41401512X
Molecular Formula: C28H22F3N7O   Molecular Weight: 529.51579   InChIKey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). In June 2006, a Phase I clinical trial found nilotinib has a relatively favorable safety profile and shows activity in cases of CML resistant to treatment with imatinib (Gleevec®), another tyrosine kinase inhibitor currently used as a first-line treatment. [Wikipedia]   From: DrugBank
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