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Compound Summary for: CID 6442177

everolimus

Also known as: Afinitor; Certican; SDZ-RAD; RAD001; Zortress; UNII-9HW64Q8G6G; Everolimus [USAN]; 42-O-(2-Hydroxyethyl)rapamycin
Molecular Formula: C53H83NO14   Molecular Weight: 958.22442   InChIKey: HKVAMNSJSFKALM-GKUWKFKPSA-N
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein.   From: DrugBank
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