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Compound Summary for: CID 6436030


Also known as: rapamycin; UNII-W36ZG6FT64; Rapammune; Rapamune; CCRIS 9024; HSDB 7284; (-)-Rapamycin; Antibiotic AY 22989; Perceiva
Molecular Formula: C51H79NO13   Molecular Weight: 914.17186   InChIKey: QFJCIRLUMZQUOT-WMVIXHMVSA-N
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.   From: MeSH
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Use and Manufacturing
Biomedical Effects and Toxicity
Safety and Handling
Environmental Fate and Exposure Potential
Exposure Standards and Regulations
Biomolecular Interactions and Pathways
Chemical and Physical Properties
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