6419738 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 16 15 15 15 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 3 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 58 2 1 1 2 2 2 2 3 3 3 3 4 4 4 4 5 5 6 7 7 8 9 10 13 14 15 15 17 19 20 21 22 22 22 23 23 24 24 25 25 26 26 26 27 27 27 28 28 28 29 29 29 30 30 31 31 32 33 33 34 35 36 37 37 37 37 38 38 39 39 41 41 41 42 42 42 43 45 45 45 46 46 46 48 48 48 49 49 50 51 51 51 52 52 53 53 54 54 55 55 56 56 57 49 50 6 9 10 12 8 11 14 16 11 13 17 18 31 32 29 30 65 33 76 77 39 79 38 82 86 44 47 50 32 34 35 35 36 34 43 40 43 40 80 81 44 45 83 47 48 89 30 31 59 32 60 33 61 62 63 64 36 66 40 38 39 41 42 44 67 68 69 70 71 72 73 74 75 78 46 84 85 47 87 88 49 90 91 92 93 51 52 94 95 53 54 55 96 56 97 57 98 57 99 100 1 1 1 1 1 2 1 1 1 2 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 1 1 1 2 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 2 1 2 1 1 1 1 29 6 30 31 59 3 1 30 7 29 32 60 3 1 31 5 29 33 61 3 1 32 5 22 30 62 3 1 38 15 37 44 67 3 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 4.8247 18.0489 14.7986 13.5135 15.802 18.1517 18.1479 15.106 17.9461 19.0436 14.4913 17.0542 12.5357 13.847 9.6023 15.7502 13.7231 13.3039 10.6358 8.0655 3.1765 16.0777 16.0777 14.2655 13.3994 14.2655 8.9876 6.4173 17.3417 17.3399 16.3912 16.3884 16.0838 15.1315 16.6613 15.1315 11.2505 10.2727 12.2283 14.2655 11.4601 11.0409 13.3994 9.9654 8.6802 7.7024 7.3951 6.1099 5.1321 3.847 3.5396 2.5618 2.2544 1.8914 1.2766 0.9136 0.6062 9.4537 18.0984 17.2055 15.5519 15.5486 16.6979 16.1065 18.7148 17.2813 10.534 12.8424 12.251 12.0664 11.5901 10.8539 10.4347 10.911 11.6472 18.4483 19.4072 12.8625 13.7171 13.7285 14.8024 8.9961 8.5719 9.2943 8.7029 14.3131 7.0883 7.6797 6.0016 6.724 6.1326 4.518 5.1094 4.1537 3.5623 2.6701 2.082 1.0861 0.4979 0 16.134 6.9537 7.7961 8.9573 4.8753 5.959 3.7834 6.8445 7.9484 7.0565 8.7477 6.8509 9.1669 7.4887 9.7957 8.1034 9.935 7.9795 12.2312 14.5536 15.6016 3.1147 1.5053 3.31 1.81 0.31 11.6989 14.0212 5.3726 4.3726 5.6833 4.0652 6.6349 2.81 2.31 1.81 10.3281 10.5377 10.1185 1.31 11.3058 9.3503 2.81 11.4893 12.6504 12.8601 13.8116 14.9728 15.1824 16.3436 17.2952 17.5048 18.4564 16.7628 18.666 16.9724 17.924 21.2552 4.9854 3.5333 5.8177 3.9337 6.7201 7.2545 4.0346 2.31 9.7288 10.2037 10.738 11.1759 11.9121 11.4358 9.4802 8.744 9.2203 8.312 6.5543 3.12 6.8825 0 0 9.9256 11.2388 12.7357 13.27 10.1256 12.7748 12.2405 13.5612 15.0581 15.5924 15.0972 14.5629 17.3804 17.9148 18.9164 16.1729 19.256 16.5124 18.054 8 8 8 8 8 8 8 8 3 3 3 3 8 8 3 8 8 8 8 8 8 22 22 23 23 24 24 25 25 29 30 31 32 34 36 38 52 52 53 54 55 56 34 35 35 36 34 43 40 43 59 60 61 62 36 40 67 53 54 55 56 57 57 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.408 Cactvs xemistry.com 2012.11.26 1530 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.408 Cactvs xemistry.com 2012.11.26 22 Count Hydrogen Bond Donor 5 E_NHDONORS 3.408 Cactvs xemistry.com 2012.11.26 9 Count Rotatable Bond 5 E_NROTBONDS 3.408 Cactvs xemistry.com 2012.11.26 22 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.408 Cactvs xemistry.com 2012.11.26 00000371F87BBE034000000000000000000000000001624000003C400000000000005801FC00001E04100820000E1CE5DF06B7F0BFCC1718A8432773748282802D3110B009D8A16854988B783AE0DD509E64082F9602FB8827FAB8828F00000000000000000000000000000000000000000000 IUPAC Name Allowed 1 2.2.0 LexiChem openeye.com 2012.11.26 S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] 2-phenylethanethioate;lithium IUPAC Name CAS-like Style 1 2.2.0 LexiChem openeye.com 2012.11.26 lithium;2-phenylethanethioic acid S-[2-[[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-2-oxolanyl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethyl-1-oxobutyl]amino]-1-oxopropyl]amino]ethyl] ester IUPAC Name Preferred 1 2.2.0 LexiChem openeye.com 2012.11.26 S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 2-phenylethanethioate;lithium IUPAC Name Systematic 1 2.2.0 LexiChem openeye.com 2012.11.26 S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 2-phenylethanethioate;lithium IUPAC Name Traditional 1 2.2.0 LexiChem openeye.com 2012.11.26 lithium;2-phenylethanethioic acid S-[2-[3-[[4-[[(5-adenin-9-yl-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl)methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] ester InChI Standard 1 1.0.4 InChI iupac.org 2012.11.26 InChI=1S/C29H42N7O17P3S.Li/c1-29(2,24(40)27(41)32-9-8-19(37)31-10-11-57-20(38)12-17-6-4-3-5-7-17)14-50-56(47,48)53-55(45,46)49-13-18-23(52-54(42,43)44)22(39)28(51-18)36-16-35-21-25(30)33-15-34-26(21)36;/h3-7,15-16,18,22-24,28,39-40H,8-14H2,1-2H3,(H,31,37)(H,32,41)(H,45,46)(H,47,48)(H2,30,33,34)(H2,42,43,44); InChIKey Standard 1 1.0.4 InChI iupac.org 2012.11.26 PQZFFEIEACTQRR-UHFFFAOYSA-N Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 892.173078 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 C29H42LiN7O17P3S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 892.607766 SMILES Canonical 1 1.9.0 OEChem openeye.com 2012.11.26 [Li].CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)CC4=CC=CC=C4)O SMILES Isomeric 1 1.9.0 OEChem openeye.com 2012.11.26 [Li].CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)CC4=CC=CC=C4)O Topological Polar Surface Area 7 E_TPSA 3.408 Cactvs xemistry.com 2012.11.26 389 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 892.173078 58 5 0 5 0 0 0 0 2 12