6409017
1
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43
44
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46
47
48
49
50
51
16
9
8
7
7
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6
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6
6
6
6
6
6
6
6
6
6
6
6
6
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6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
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25
25
26
26
27
27
28
29
29
30
30
13
15
31
14
10
12
14
6
11
13
32
9
11
17
13
18
19
33
34
16
21
22
15
35
36
24
25
20
37
23
38
32
39
40
23
41
26
42
27
43
44
29
45
30
46
28
47
28
48
49
31
50
31
51
1
1
1
2
1
1
1
1
2
2
3
1
1
2
1
2
1
1
1
1
2
1
1
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2
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2
1
1
1
2
1
1
1
1
2
1
2
1
1
1
1
2
1
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
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43
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48
49
50
51
1.2712
-6.0001
2.428
3.29
-1.2281
-0.222
5.4513
-2.0148
-0.9768
4.243
-2.0938
2.8754
-0.1091
2.7672
2.6696
-3.1077
-2.919
-0.8529
3.7164
-2.7872
1.6232
3.7617
-1.7561
-2.8812
-4.311
1.2252
3.3639
2.0956
-3.8585
-5.2882
-5.0619
4.6866
4.4985
5.1958
2.5385
3.5939
-3.7362
-0.0665
3.4664
2.7833
-3.489
0.9091
4.7624
-1.6555
-1.9482
-4.5028
0.2341
4.0429
1.7853
-3.6827
-6.2253
3.0184
-3.6025
2.2942
0.215
-0.0047
0.86
-2.8674
1.4715
2.3642
-0.4206
0.3019
-0.5017
2.0086
1.5054
1.9025
-0.7115
1.7835
3.5609
-1.7328
2.9746
-0.2572
-1.3789
3.8616
-1.7579
-0.6412
-0.9454
-2.0671
-1.8503
-2.7344
-1.6178
-2.6645
-2.3662
0.2615
-0.5638
1.028
2.415
1.1191
4.2831
-2.4486
-1.5445
3.2106
0.4098
-1.5606
4.7879
-1.8266
0.1682
-0.7834
-2.7687
-2.3871
-3.5494
-1.5638
1.8957
0.0131
-0.752
-0.11
1.7716
2.0678
3.0007
0.0333
0.3393
0.8127
0.7811
-1.3018
1.3661
0.1339
1.5996
0.5817
-0.9957
-0.3863
1.3811
-1.7108
-1.7945
-1.8633
-1.4066
-0.3121
1.2834
-2.9407
-3.0095
-3.5482
-0.5043
1.0913
0.1975
2.2861
1.6301
0.2891
2.2418
1.8823
-1.264
-0.1875
0.5919
1.926
-2.5055
-1.3262
-1.4911
-1.9648
-0.8668
1.9839
-3.3546
-3.4856
-4.4399
-1.2001
1.6374
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0061CB3900000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
111.5246
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
42.225
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10764073 3 17127367929846494441
11135609 12 18058464127205432966
12202916 173 17624658338263837076
12293681 25 17986672562983078500
12422481 6 17918267675390232811
15484559 13 17614858738817633828
15664445 248 17972605651915445717
17809404 112 17914322486115180494
1813 80 18263937703582714029
18603816 31 17318714778681804234
19315092 285 18040711472593488298
1979834 28 17203336649109114275
20775530 9 18340491157052326597
21285901 2 18265616661885557549
21781051 124 17679881318891922081
21987440 362 16672729607977569220
23559900 14 17488203524955243559
25222932 49 18410571833916622850
25265897 201 17620473506630008083
392239 28 15194702529995849706
44062 13 18189325775817504032
57527585 103 18057047895609380561
613672 6 17987790800963819696
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
629.33
10.64
4.79
3.16
2.82
1.6
1.11
-12.37
-4.32
3.19
0.41
-4.54
-1.71
1.54
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1361.346
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
348
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
1
330
300
88
77
49
205
328
213
143
157
193
326
312
112
33
82
126
56
303
29
228
66
286
10
333
179
274
158
135
253
106
7
160
220
207
237
156
42
165
150
190
54
227
94
149
132
316
85
230
280
76
75
203
5
242
96
226
325
313
320
177
50
335
124
67
331
295
221
52
282
209
334
332
117
299
2
137
11
210
128
53
204
200
61
290
327
40
105
323
187
294
28
100
6
81
264
329
39
101
47
45
219
155
178
25
169
58
198
201
194
8
196
109
119
13
283
241
113
62
291
251
222
322
235
68
134
234
34
218
30
260
122
43
336
309
171
276
35
138
123
37
95
168
121
130
162
9
32
108
281
195
216
189
118
51
307
84
92
89
46
27
188
285
70
153
297
206
229
250
324
176
202
78
41
170
302
44
279
239
4
243
186
60
252
125
304
103
277
98
152
163
86
175
288
184
63
17
314
144
261
199
293
255
139
148
197
247
104
248
301
154
114
55
215
116
298
167
21
259
23
192
172
180
208
225
26
14
254
142
71
140
147
57
133
141
127
59
270
87
3
246
305
38
110
31
185
181
64
191
22
107
20
268
263
308
265
97
115
146
315
12
266
269
289
24
15
240
287
217
99
159
73
83
211
161
317
212
19
48
18
91
164
131
36
72
145
296
306
16
233
256
311
257
224
183
151
136
232
65
174
80
111
272
319
93
273
223
231
182
292
258
238
249
284
278
310
166
129
79
173
262
318
236
244
271
214
120
74
245
267
69
102
275
90
321
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
42
1 -0.33
10 0.3
11 0.31
12 0.12
13 0.41
14 0.57
15 0.29
17 -0.15
18 -0.15
19 0.2
2 -0.19
20 -0.15
21 -0.15
22 -0.15
23 -0.15
24 -0.15
25 -0.15
26 -0.15
27 -0.15
28 -0.15
29 -0.15
3 -0.57
30 -0.15
31 0.19
32 0.36
37 0.15
38 0.15
4 -0.48
41 0.15
42 0.15
43 0.15
44 0.15
45 0.15
46 0.15
47 0.15
48 0.15
49 0.15
5 -0.31
50 0.15
51 0.15
6 -0.31
7 -0.56
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
8
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
8
1 3 acceptor
1 5 acceptor
1 6 acceptor
1 7 acceptor
6 12 21 22 26 27 28 rings
6 16 24 25 29 30 31 rings
6 5 6 8 9 11 13 rings
6 8 9 17 18 20 23 rings
32
0
0
0
0
0
0
0
1
1