6374482 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 17 16 8 8 8 8 8 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 5 6 7 7 8 8 8 9 10 10 10 11 11 12 12 12 13 13 14 15 16 16 17 17 18 19 19 20 20 20 22 22 23 23 24 24 25 25 26 26 28 28 28 29 29 30 30 31 31 32 32 33 33 34 3 4 11 13 14 15 27 28 10 14 15 21 11 12 35 36 37 13 38 39 40 41 16 17 18 19 18 21 20 22 42 43 44 45 23 24 25 46 26 47 27 48 27 49 29 50 51 30 31 32 52 33 53 34 54 34 55 1 2 2 1 1 2 2 1 1 1 1 1 3 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 1 1 2 1 1 1 2 1 2 1 1 1 1 1 1 2 1 1 1 2 1 2 1 1 1 10 8 11 12 35 3 1 16 14 18 19 42 22 2 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 2.866 5.9641 5.9641 6.9152 3.732 7.1962 3.732 5.4641 8.0622 5.4641 6.2731 4.6551 4.9641 4.5981 6.3301 4.5981 6.3301 5.4641 3.732 5.4641 7.1962 3.732 4.5981 2.866 4.5981 2.866 3.732 2.866 2.866 3.732 2 3.732 2 2.866 6.2215 6.8395 6.5831 4.3451 4.0887 4.3576 5.0289 3.1951 6.0841 5.4641 4.8441 5.135 2.3291 5.135 2.3291 2.2554 2.654 4.269 1.4631 4.269 1.4631 7.0194 -6.0194 -7.0194 -6.3284 -3.4806 -3.4806 2.5194 -3.4806 -0.9806 -4.4806 -5.0684 -5.0684 -6.0194 -2.9806 -2.9806 -1.9806 -1.9806 -1.4806 -1.4806 -0.4806 -1.4806 -0.4806 0.0194 0.0194 1.0194 1.0194 1.5194 3.0194 4.0194 4.5194 4.5194 5.5194 5.5194 6.0194 -4.0947 -5.3205 -4.5314 -4.5314 -5.3205 -6.1483 -6.636 -1.7906 -0.4806 0.1394 -0.4806 -0.2906 -0.2906 1.3294 1.3294 3.1271 2.4368 4.2094 4.2094 5.8294 5.8294 3 8 8 8 8 8 8 8 8 8 8 8 8 10 22 22 23 24 25 26 29 29 30 31 32 33 35 23 24 25 26 27 27 30 31 32 33 34 34 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.384 Cactvs xemistry.com 2011.09.13 1030 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.384 Cactvs xemistry.com 2011.09.13 6 Count Hydrogen Bond Donor 5 E_NHDONORS 3.384 Cactvs xemistry.com 2011.09.13 0 Count Rotatable Bond 5 E_NROTBONDS 3.384 Cactvs xemistry.com 2011.09.13 5 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.384 Cactvs xemistry.com 2011.09.13 00000371E07B3800440000000000000000000000000120000000306080000000000000014000001E06000000000C2EE5D826B2068300040A980621521070E208002025100888010E0AC80CA632A5B31A863820A4C631A8A98780C0200E24000000000000004800000000000000000000000000 IUPAC Name Allowed 1 2.0.2 LexiChem openeye.com 2011.09.13 (5E)-5-[[4-[(4-chlorophenyl)methoxy]phenyl]methylene]-1-(1,1-dioxothiolan-3-yl)-4-methyl-2,6-dioxo-pyridine-3-carbonitrile IUPAC Name CAS-like Style 1 2.0.2 LexiChem openeye.com 2011.09.13 (5E)-5-[[4-[(4-chlorophenyl)methoxy]phenyl]methylidene]-1-(1,1-dioxo-3-thiolanyl)-4-methyl-2,6-dioxo-3-pyridinecarbonitrile IUPAC Name Preferred 1 2.0.2 LexiChem openeye.com 2011.09.13 (5E)-5-[[4-[(4-chlorophenyl)methoxy]phenyl]methylidene]-1-(1,1-dioxothiolan-3-yl)-4-methyl-2,6-dioxopyridine-3-carbonitrile IUPAC Name Systematic 1 2.0.2 LexiChem openeye.com 2011.09.13 (5E)-1-[1,1-bis(oxidanylidene)thiolan-3-yl]-5-[[4-[(4-chlorophenyl)methoxy]phenyl]methylidene]-4-methyl-2,6-bis(oxidanylidene)pyridine-3-carbonitrile IUPAC Name Traditional 1 2.0.2 LexiChem openeye.com 2011.09.13 (5E)-5-[4-(4-chlorobenzyl)oxybenzylidene]-1-(1,1-diketothiolan-3-yl)-2,6-diketo-4-methyl-nicotinonitrile InChI Standard 1 1.0.3 InChI nist.gov 2011.09.13 InChI=1S/C25H21ClN2O5S/c1-16-22(24(29)28(25(30)23(16)13-27)20-10-11-34(31,32)15-20)12-17-4-8-21(9-5-17)33-14-18-2-6-19(26)7-3-18/h2-9,12,20H,10-11,14-15H2,1H3/b22-12+ InChIKey Standard 1 1.0.3 InChI nist.gov 2011.09.13 QUNRDYCPVGRBCD-WSDLNYQXSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2011.09.13 3.3 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 496.08597 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 C25H21ClN2O5S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 496.96264 SMILES Canonical 1 1.7.4 OEChem openeye.com 2011.09.13 CC1=C(C(=O)N(C(=O)C1=CC2=CC=C(C=C2)OCC3=CC=C(C=C3)Cl)C4CCS(=O)(=O)C4)C#N SMILES Isomeric 1 1.7.4 OEChem openeye.com 2011.09.13 CC\1=C(C(=O)N(C(=O)/C1=C/C2=CC=C(C=C2)OCC3=CC=C(C=C3)Cl)C4CCS(=O)(=O)C4)C#N Topological Polar Surface Area 7 E_TPSA 3.384 Cactvs xemistry.com 2011.09.13 113 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 496.08597 34 1 0 1 1 1 0 0 1 1