Bookmark and Share

Compound Summary for: CID 62959


Also known as: Trovan, TVFX, Trovafloxacin [INN], Trovan (oral), Fluorinated quinolone, UNII-9F388J00UK, Trovafloxacin (INN), 147059-72-1
Molecular Formula: C20H15F3N4O3   Molecular Weight: 416.35331   InChIKey: WVPSKSLAZQPAKQ-SOSAQKQKSA-N
Trovafloxacin (sold as Trovan by Pfizer) is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was withdrawn from the market due to the risk of hepatotoxicity. It had better gram-positive bacterial coverage and less gram-negative coverage than the previous fluoroquinolones. [Wikipedia]   From: DrugBank
Show subcontent titlesTable of Contents
Related Records
show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)
Use and Manufacturing
Biomedical Effects and Toxicity
Biomolecular Interactions and Pathways
Biological Test Results
Chemical and Physical Properties
_ _