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Compound Summary for: CID 62959

trovafloxacin

Also known as: Trovan, TVFX, Trovafloxacin [INN], Trovan (oral), Fluorinated quinolone, UNII-9F388J00UK, Trovafloxacin (INN), 147059-72-1
Molecular Formula: C20H15F3N4O3   Molecular Weight: 416.35331   InChIKey: WVPSKSLAZQPAKQ-SOSAQKQKSA-N
Trovafloxacin (sold as Trovan by Pfizer) is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was withdrawn from the market due to the risk of hepatotoxicity. It had better gram-positive bacterial coverage and less gram-negative coverage than the previous fluoroquinolones. [Wikipedia]   From: DrugBank
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