Colchicine - PubChem

Colchicine - Compound Summary (CID 6167) Also known as: Colchicin, Colchicina, Condylon, Colsaloid, Colchicinum, Colchineos, Colchisol, Colcin, 64-86-8 Molecular Formula: C₂₂H₂₅NO₆ Molecular Weight: 399.437 InChIKey: IAKHMKGGTNLKSZ-INIZCTEOSA-N A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). From: MeSH View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
Show subcontent titlesHide subcontent titlesTable of Contents Identification Depositor-Supplied Synonyms Compound Information Related Records Related Compounds with Annotation Related Compounds Related Substances Use and Manufacturing Medication Information Patents Methods of Manufacturing Impurities Formulations/Preparations Consumption Patterns Use and Manufacturing References Pharmacology Pharmacological Action Therapeutic Uses Drug Warning Minimum/Potential Fatal Human Dose Biomedical Effects and Toxicity Absorption, Distribution and Excretion Metabolism/Metabolites Biological Half-Life Mechanism of Action Interactions Toxicity Summary Antidote and Emergency Treatment Human Toxicity Excerpts Non-Human Toxicity Excerpts Non-Human Toxicity Values Populations at Special Risk Toxicology References Safety and Handling Safety References Fire Potential NFPA Hazard Classification Fire Fighting Procedures Toxic Combustion Products Other Fire Fighting Hazards Decomposition Skin, Eye, and Respiratory Irritations Protective Equipment and Clothing Other Preventative Measures Stability/Shelf Life Cleanup Methods Disposal Methods Environmental Fate and Exposure Potential Environmental Fate/Exposure Summary Natural Occurring Sources Artificial Sources Environmental Fate Abiotic Degredation Bioconcentration Soil Adsorption/Mobility Volatilization from Water/Soil Water Concentrations Milk Concentrations Probable Routes of Human Exposure Body Burdens Exposure Standards and Regulations CERCLA Reportable Quantities FDA Requirements Monitoring and Analysis Methods Analytic Laboratory Methods Clinical Laboratory Methods Literature Depositor Provided PubMed Citations NLM Curated PubMed Citations Patents Depositor-Supplied Patent Identifiers Biomolecular Interactions and Pathways Protein Bound 3-D Structures Biosystems and Pathways Interactions Target Enzyme Transporter Action General Function Specific Function Gene Name GenBank Gene GenBank Protein References Biological Test Results BioAssay Results Classification Ontologies Substance Categorization Classification Chemical and Physical Properties Color/Form Odor Melting Point Dissociation Constants Octanol/Water Partition Coefficient pH Solubilities Spectral Properties Vapor Pressure Other Chemical/Physical Properties Computed Properties Expand all sub-sections	2D Structure 3D Conformer
Identification Help top of page Related Records Help top of page show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)show first sub-section only Use and Manufacturing Help top of page show all 7 sub-sections (Medication Information, Patents, Methods of Manufacturing, Impurities, Formulations/Preparations ...)show first sub-section only Pharmacology Help top of page show all 4 sub-sections (Pharmacological Action, Therapeutic Uses, Drug Warning, Minimum/Potential Fatal Human Dose)show first sub-section only Biomedical Effects and Toxicity Help top of page show all 12 sub-sections (Absorption, Distribution and Excretion, Metabolism/Metabolites, Biological Half-Life ...)show first sub-section only Safety and Handling Help top of page show all 13 sub-sections (Safety References, Fire Potential, NFPA Hazard Classification, Fire Fighting Procedures ...)show first sub-section only Environmental Fate and Exposure Potential Help top of page show all 12 sub-sections (Environmental Fate/Exposure Summary, Natural Occurring Sources, Artificial Sources ...)show first sub-section only Exposure Standards and Regulations Help top of page show all 2 sub-sections (CERCLA Reportable Quantities, FDA Requirements)show first sub-section only Monitoring and Analysis Methods Help top of page show all 2 sub-sections (Analytic Laboratory Methods, Clinical Laboratory Methods)show first sub-section only Literature Help top of page show all 2 sub-sections (Depositor Provided PubMed Citations, NLM Curated PubMed Citations)show first sub-section only Patents Help top of page Biomolecular Interactions and Pathways Help top of page show all 3 sub-sections (Protein Bound 3-D Structures, Biosystems and Pathways, Interactions)show first sub-section only Biological Test Results Help top of page Data Analysis Data Download BioActivity Summary: This Compound with Similar Compounds with Similar Conformers Classification Help top of page show all 2 sub-sections (Ontologies, Substance Categorization Classification)show first sub-section only Chemical and Physical Properties Help top of page show all 11 sub-sections (Color/Form, Odor, Melting Point, Dissociation Constants, Octanol/Water Partition Coefficient ...)show first sub-section only

_