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Compound Summary for: CID 61

2,3-Diphosphoglycerate

Also known as: 2,3-Bisphosphoglycerate; 2,3-Bisphosphoglyceric acid; 2,3-Diphosphoglyceric acid; 2,3-bis(phosphonooxy)propanoic acid; 2,3-Dpg; 138-81-8
Molecular Formula: C3H8O10P2   Molecular Weight: 266.037144   InChIKey: XOHUEYCVLUUEJJ-UHFFFAOYSA-N
A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)   From: MeSH
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