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Compound Summary for: CID 60823

atorvastatin

Also known as: Cardyl, Sotis, Tozalip, Xavator, 134523-00-5, Torvast, Lipitor, atorvastatina, atorvastatine
Molecular Formula: C33H35FN2O5   Molecular Weight: 558.639803   InChIKey: XUKUURHRXDUEBC-KAYWLYCHSA-N
Atorvastatin (Lipitor) is a member of the drug class known as statins. It is used for lowering cholesterol. Atorvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate. Atorvastatin acts primarily in the liver. Decreased hepatic cholesterol levels increases hepatic uptake of cholesterol and reduces plasma cholesterol levels.    From: DrugBank
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