Bookmark and Share

Compound Summary for: CID 60823


Also known as: Cardyl; Sotis; Tozalip; Xavator; 134523-00-5; Torvast; Lipitor; atorvastatina; atorvastatine
Molecular Formula: C33H35FN2O5   Molecular Weight: 558.639803   InChIKey: XUKUURHRXDUEBC-KAYWLYCHSA-N
Atorvastatin (Lipitor) is a member of the drug class known as statins. It is used for lowering cholesterol. Atorvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate. Atorvastatin acts primarily in the liver. Decreased hepatic cholesterol levels increases hepatic uptake of cholesterol and reduces plasma cholesterol levels.    From: DrugBank
Show subcontent titlesTable of Contents
Related Records
show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)
Use and Manufacturing
Biomedical Effects and Toxicity
Safety and Handling
Biomolecular Interactions and Pathways
Biological Test Results
Chemical and Physical Properties
_ _