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Compound Summary for: CID 60795


Also known as: Abilify; Abilitat; 129722-12-9; Abilify Discmelt; OPC-14597; Discmelt; Opc 14597; aripiprazol; aripiprazolum
Molecular Formula: C23H27Cl2N3O2   Molecular Weight: 448.38538   InChIKey: CEUORZQYGODEFX-UHFFFAOYSA-N
Aripiprazole is an atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. Aripiprazole appears to mediate its antipsychotic effects primarily by partial agonism at the D2 receptor. In addition to partial agonist activity at the D2 receptor, aripiprazole is also a partial agonist at the 5-HT1A receptor, and like the other atypical antipsychotics, aripiprazole displays an antagonist profile at the 5-HT2A receptor. Aripiprazole has moderate affinity for histamine and alpha adrenergic receptors, and no appreciable affinity for cholinergic muscarinic receptors.   From: DrugBank
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