60552446 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 16 8 8 8 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 3 4 4 5 5 5 6 6 6 7 7 8 8 8 9 9 9 10 10 10 11 11 11 12 12 12 13 13 14 14 14 15 15 15 16 16 17 17 18 18 19 19 20 20 21 21 22 23 24 24 24 25 26 27 28 28 29 29 30 30 31 32 33 34 34 34 35 35 35 26 27 23 31 34 32 35 8 14 15 19 23 58 25 27 9 10 36 11 39 40 12 37 38 13 43 44 13 41 42 45 46 16 47 48 49 50 51 17 18 19 20 21 52 53 54 22 55 22 56 57 24 25 59 60 26 61 28 29 30 31 62 33 63 32 33 64 65 66 67 68 69 70 1 1 2 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 2 1 1 1 1 1 1 2 1 1 2 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 8.4627 7.9671 5.9216 7.6537 3.808 6.3848 6.8446 3.4013 2.4067 3.989 2 3.5823 2.5878 4.8025 3.2202 5.2092 6.2038 4.6215 6.7916 6.6105 5.0282 6.0227 6.9726 6.5659 7.1537 8.1537 7.6537 7.6537 6.7876 8.5197 6.7876 7.6537 8.5197 5.0556 8.5197 4.0179 4.503 4.4197 2.45 1.8052 3.5391 4.1839 1.486 1.5693 2.0305 2.7587 4.7593 5.4041 3.7218 2.8558 2.7186 4.0049 7.3056 7.2222 7.2271 4.6638 6.2749 5.7682 6.0519 6.1352 8.5181 6.2507 9.0566 9.0566 5.3656 4.5186 4.7456 8.2097 9.0566 8.8297 -0.92 1.8582 -4.5078 -5.5078 3.1626 2.5626 -0.92 2.2491 2.1445 1.44 1.231 0.5265 0.422 3.2671 3.9716 4.1807 4.2852 4.9897 3.4762 5.1988 5.9032 6.0078 1.7536 0.8401 0.0311 0.0311 -1.5078 -2.5078 -3.0078 -3.0078 -4.0078 -4.5078 -4.0078 -4.0078 -6.0078 2.3139 1.0934 1.886 2.763 2.2945 -0.092 0.3765 1.5777 0.785 0.1502 -0.174 2.6486 3.1171 4.336 4.4732 3.6072 4.9249 3.1295 3.9222 5.2636 6.4048 6.5742 2.4978 1.1868 0.3941 0.5327 -2.6978 -2.6978 -4.3178 -3.4708 -3.6978 -4.5447 -6.5447 -6.3178 -5.4708 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 1 1 7 7 16 16 17 18 20 21 25 28 28 29 30 31 32 26 27 25 27 17 18 20 21 22 22 26 29 30 31 33 32 33 0 Compound Canonicalized 5 2012.05.21 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 647 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 6 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 1 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 10 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371F07B30004000000000000000000000000001600000003060C000000000000001D000001E04100000000C2CC5DE06B28793C81408AC032572540082F8A0612A380888B53EAC980D26BAA4F51B84302A64D611AAA807B0D0920EA0000100001040004000020000208000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 N-[[2-[[cyclohexyl(methyl)amino]methyl]phenyl]methyl]-2-[2-(3,4-dimethoxyphenyl)thiazol-4-yl]acetamide IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 N-[[2-[[cyclohexyl(methyl)amino]methyl]phenyl]methyl]-2-[2-(3,4-dimethoxyphenyl)-4-thiazolyl]acetamide IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 N-[[2-[[cyclohexyl(methyl)amino]methyl]phenyl]methyl]-2-[2-(3,4-dimethoxyphenyl)-1,3-thiazol-4-yl]acetamide IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 N-[[2-[[cyclohexyl(methyl)amino]methyl]phenyl]methyl]-2-[2-(3,4-dimethoxyphenyl)-1,3-thiazol-4-yl]ethanamide IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 N-[2-[[cyclohexyl(methyl)amino]methyl]benzyl]-2-[2-(3,4-dimethoxyphenyl)thiazol-4-yl]acetamide InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C28H35N3O3S/c1-31(24-11-5-4-6-12-24)18-22-10-8-7-9-21(22)17-29-27(32)16-23-19-35-28(30-23)20-13-14-25(33-2)26(15-20)34-3/h7-10,13-15,19,24H,4-6,11-12,16-18H2,1-3H3,(H,29,32) InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 COYUWNBXKHXILA-UHFFFAOYSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 4.9 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 493.239913 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C28H35N3O3S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 493.6608 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CN(CC1=CC=CC=C1CNC(=O)CC2=CSC(=N2)C3=CC(=C(C=C3)OC)OC)C4CCCCC4 SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CN(CC1=CC=CC=C1CNC(=O)CC2=CSC(=N2)C3=CC(=C(C=C3)OC)OC)C4CCCCC4 Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 91.9 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 493.239913 35 0 0 0 0 0 0 0 1 2