60194027
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
8
8
8
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
4
5
5
5
6
6
6
7
7
8
8
8
8
9
9
10
10
11
11
12
12
13
14
14
15
15
16
17
17
17
18
19
19
19
20
20
20
21
21
21
22
22
23
23
24
24
25
25
25
26
26
27
27
28
28
30
30
31
31
32
33
34
34
34
16
22
59
29
34
9
10
16
11
14
21
13
18
25
32
33
9
10
11
12
35
36
37
38
39
40
13
15
14
22
41
18
24
17
19
20
42
26
23
43
44
23
45
46
27
47
48
51
52
49
50
28
53
54
55
56
29
57
30
31
29
58
32
60
33
61
62
63
64
65
66
2
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
2
1
2
1
1
1
1
1
2
1
1
1
1
1
1
14
5
13
22
41
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
3.5893
-3.1497
2.5006
2.3104
-1.9562
-0.9958
-6.5984
0.5535
1.9414
0.9979
-0.5954
0.2652
-0.9939
-2.1661
1.0697
3.4921
4.6767
0.2493
5.9796
4.6386
-2.3352
-2.437
6.1694
2.3985
-2.1339
0.7005
-3.8276
2.8605
2.0234
-4.3856
-4.6534
-5.7639
-6.0199
1.5951
2.5511
1.9473
0.5346
1
-0.4682
-0.5244
-3.0562
4.8812
5.8401
6.7549
4.2994
4.0986
-1.832
-2.0242
6.7309
6.5879
-3.0719
-1.5179
3.0723
-2.0856
-3.0652
-2.0981
0.0132
3.8875
-3.3196
-3.7729
-4.2541
-6.2486
-6.707
2.1391
0.7468
1.2773
-2.5504
1.4571
5.3838
-1.8523
-1.3523
2.2655
-1.5602
-1.073
-1.4614
-1.6644
-1.834
0.458
0.9073
0.0839
1.562
-2.2622
-2.3309
2.6921
-2.9843
-3.4275
-1.6764
0.2528
-3.5328
1.7436
3.151
3.987
-1.6354
3.0337
4.1374
-0.7785
-2.4546
-0.7787
-2.3798
6.4737
-0.6525
-2.305
-2.6115
-0.9815
-1.7368
-2.9124
0.4426
-1.3376
-3.7683
-2.2948
-3.1126
-4.336
-1.0246
-2.7003
-2.8617
-4.5395
-0.5578
0.2832
0.9008
3.9187
2.6032
3.6139
4.8132
3.1668
1.5527
-0.1242
-3.139
-0.1283
-2.9988
7.3862
6.3982
6.5857
2.1171
-2.7938
0.8559
0.3544
-0.799
-0.543
1.1313
-0.4251
-0.9901
0.9374
-1.1361
-0.3772
-0.6916
-1.1142
-0.0057
0.9191
-0.0612
-0.1264
0.4452
-1.1459
0.5753
-2.6137
-0.9845
0.4289
-0.6702
0.1558
0.7698
0.7148
0.5778
1.7122
0.0081
1.8531
0.2251
0.6966
-1.4007
-1.6875
1.2294
1.792
-2.2229
-0.9426
-0.586
-0.4905
1.1986
0.7895
-2.136
-0.8547
1.3005
0.8237
-1.6446
-1.0571
-2.9888
-3.2094
0.546
0.1067
-0.5242
-1.659
0.0296
1.0463
-3.7464
2.3228
-0.7327
2.5737
-0.3424
0.9621
1.3855
-0.3457
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2012.05.21
03967CEB00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
100.9058
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
66.153
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10032420 55 17749107742853593523
10411042 1 18411704244888514278
1100329 8 18194396684732728061
11227688 84 18124864673394474719
11297750 10 18187359926906423949
11488393 25 18338508754878065924
12107183 9 18270133310013808147
12293681 160 17470979529240484077
12422481 6 17988641861333574379
12788726 201 18043818589211195786
12988421 55 17620453041100149992
13140716 1 18267019458144179536
13540713 4 18115005490451197685
13673619 4 18040725744601072871
13785724 45 18342468019072287482
14114211 80 17472146544927370628
14363568 33 18339360872490348104
14444916 359 17977668937869881076
14739800 52 17416968524712844403
14790565 3 17617099543852813181
14849402 71 18268159810351872170
14955137 171 18341054021175220486
15064981 194 17904783089569047292
15081414 286 18340759429958796464
15420108 30 17912927476505886359
15444296 121 18124885560099457265
15775530 1 18042382734351237237
15927050 60 17837216239868016710
17980427 26 17983013650363247916
20028762 73 16969993047540064286
20101258 96 18339359643549231902
20642791 268 18130801044431420067
21639891 77 18190459363705496980
22182313 1 17678154157701208519
22311459 1 18266743674336798064
22440779 20 17459486472003526861
244849 19 17968639623775103991
3411729 13 18126575745583150235
3418910 222 18337961083315306404
3552219 110 17825420451365108782
437815 12 18409170974535568903
469060 322 18196953075364081562
5171179 24 18335977636583187049
5912855 24 17902233313071799010
6058803 2 17986680479325651567
6086070 43 18337103480887641383
86090 222 17313669368486626739
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
662.17
11.95
7.31
1.71
4.86
13.35
0.6
-17.96
-3.42
-9.56
-1.6
1.45
-0.33
2.4
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1451.167
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
360.4
Conformer
RMSD
7
2012.05.21
1
Diverse Conformer
ID List
6
2012.05.21
1
4
15
14
8
16
11
3
9
6
18
7
12
17
10
20
2
13
19
5
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
38
1 -0.57
10 0.22
11 0.27
12 -0.16
13 -0.33
14 0.45
16 0.58
17 0.05
18 -0.15
2 -0.68
21 0.41
22 0.28
24 -0.15
25 0.26
26 -0.15
27 -0.14
28 -0.15
29 0.08
3 -0.36
30 -0.15
31 -0.15
32 0.16
33 0.16
34 0.28
4 -0.51
5 -0.81
53 0.15
57 0.15
58 0.15
59 0.4
6 0.05
60 0.15
61 0.15
62 0.15
63 0.15
7 -0.62
8 0.16
9 0.22
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.05.21
8
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
13
1 1 acceptor
1 2 acceptor
1 2 donor
1 3 acceptor
1 5 cation
1 6 cation
1 7 acceptor
4 17 19 20 23 rings
4 4 8 9 10 rings
5 6 12 13 15 18 rings
6 15 18 24 26 28 29 rings
6 5 8 11 12 13 14 rings
6 7 27 30 31 32 33 rings
34
1
1
0
0
0
0
0
1
1