60193762 -OEChem-05102412422D 77 82 0 1 0 0 0 0 0999 V2000 6.3966 -5.3100 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 4.1900 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 4.6900 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -2.3100 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 1.0564 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 2.6900 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 2.9947 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -0.8100 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.3100 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 1.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 1.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 0.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 0.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.1900 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 6.3966 2.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -0.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -0.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 1.3853 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 2.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 3.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 2.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 4.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9652 1.6955 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7742 3.0967 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9433 1.4876 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4433 2.3536 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 0.4333 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1397 3.9452 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 2.0986 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -1.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 0.3180 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 1.1562 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -3.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 0.1448 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -3.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -3.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -4.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -4.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -5.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.1074 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 1.7977 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 1.2726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 0.5823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 0.5823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.2726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 3.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 -0.2023 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 -0.8926 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 -0.8926 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 -0.2023 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8931 3.3092 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8732 4.0823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4746 4.7726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3452 1.6955 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9004 1.0789 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2758 3.4612 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4642 3.6337 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7517 0.8979 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5097 1.2354 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9449 1.9892 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8582 2.8143 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 -0.0644 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7290 4.1379 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9471 4.5346 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5504 3.7526 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 2.6046 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 -0.2491 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 5.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6655 -2.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 0.3996 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 -0.4204 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 -0.1100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7256 -3.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -3.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -5.1200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -5.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 38 1 0 0 0 0 2 21 2 0 0 0 0 3 23 1 0 0 0 0 3 69 1 0 0 0 0 4 31 2 0 0 0 0 5 33 1 0 0 0 0 5 35 1 0 0 0 0 6 11 1 0 0 0 0 6 15 1 0 0 0 0 6 21 1 0 0 0 0 7 16 1 0 0 0 0 7 22 1 0 0 0 0 7 29 1 0 0 0 0 8 17 1 0 0 0 0 8 18 1 0 0 0 0 8 31 1 0 0 0 0 9 31 1 0 0 0 0 9 34 1 0 0 0 0 9 70 1 0 0 0 0 10 11 1 0 0 0 0 10 12 1 0 0 0 0 10 13 1 0 0 0 0 10 14 1 0 0 0 0 11 41 1 0 0 0 0 11 42 1 0 0 0 0 12 16 2 0 0 0 0 12 19 1 0 0 0 0 13 17 1 0 0 0 0 13 43 1 0 0 0 0 13 44 1 0 0 0 0 14 18 1 0 0 0 0 14 45 1 0 0 0 0 14 46 1 0 0 0 0 15 16 1 0 0 0 0 15 23 1 1 0 0 0 15 47 1 0 0 0 0 17 48 1 0 0 0 0 17 49 1 0 0 0 0 18 50 1 0 0 0 0 18 51 1 0 0 0 0 19 22 2 0 0 0 0 19 28 1 0 0 0 0 20 21 1 0 0 0 0 20 24 1 0 0 0 0 20 25 1 0 0 0 0 20 52 1 0 0 0 0 22 30 1 0 0 0 0 23 53 1 0 0 0 0 23 54 1 0 0 0 0 24 26 1 0 0 0 0 24 55 1 0 0 0 0 24 56 1 0 0 0 0 25 27 1 0 0 0 0 25 57 1 0 0 0 0 25 58 1 0 0 0 0 26 27 1 0 0 0 0 26 59 1 0 0 0 0 26 60 1 0 0 0 0 27 61 1 0 0 0 0 27 62 1 0 0 0 0 28 32 2 0 0 0 0 28 63 1 0 0 0 0 29 64 1 0 0 0 0 29 65 1 0 0 0 0 29 66 1 0 0 0 0 30 33 2 0 0 0 0 30 67 1 0 0 0 0 32 33 1 0 0 0 0 32 68 1 0 0 0 0 34 36 2 0 0 0 0 34 37 1 0 0 0 0 35 71 1 0 0 0 0 35 72 1 0 0 0 0 35 73 1 0 0 0 0 36 38 1 0 0 0 0 36 74 1 0 0 0 0 37 39 2 0 0 0 0 37 75 1 0 0 0 0 38 40 2 0 0 0 0 39 40 1 0 0 0 0 39 76 1 0 0 0 0 40 77 1 0 0 0 0 M END > 60193762 > 1 > 923 > 5 > 2 > 4 > AAADcfB7uQAAAAAAAAAAAAAAAAAAAeIAAAA8eIEAAAAAAFgB9AAAHwAQCAAADyzhng4zxvPMFgCoAyVyVACCiCAhIiAI2CE+bJiOdvLEsZuUcChu1hvY6CeY2PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > (1S)-2-(cyclopentanecarbonyl)-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1S)-2-[cyclopentyl(oxo)methyl]-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methyl-1'-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]carboxamide > (1S)-2-(cyclopentanecarbonyl)-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1S)-2-(cyclopentanecarbonyl)-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1S)-2-cyclopentylcarbonyl-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1S)-2-(cyclopentanecarbonyl)-N-(3-fluorophenyl)-7-methoxy-9-methyl-1-methylol-spiro[1,3-dihydro-beta-carboline-4,4'-piperidine]-1'-carboxamide > InChI=1S/C31H37FN4O4/c1-34-25-17-23(40-2)10-11-24(25)27-28(34)26(18-37)36(29(38)20-6-3-4-7-20)19-31(27)12-14-35(15-13-31)30(39)33-22-9-5-8-21(32)16-22/h5,8-11,16-17,20,26,37H,3-4,6-7,12-15,18-19H2,1-2H3,(H,33,39)/t26-/m1/s1 > OGFJMXOFDSVLBB-AREMUKBSSA-N > 3.5 > 548.27988384 > C31H37FN4O4 > 548.6 > CN1C2=C(C=CC(=C2)OC)C3=C1C(N(CC34CCN(CC4)C(=O)NC5=CC(=CC=C5)F)C(=O)C6CCCC6)CO > CN1C2=C(C=CC(=C2)OC)C3=C1[C@H](N(CC34CCN(CC4)C(=O)NC5=CC(=CC=C5)F)C(=O)C6CCCC6)CO > 87 > 548.27988384 > 0 > 40 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 12 16 8 12 19 8 15 23 5 19 22 8 19 28 8 22 30 8 28 32 8 30 33 8 32 33 8 34 36 8 34 37 8 36 38 8 37 39 8 38 40 8 39 40 8 7 16 8 7 22 8 $$$$