60192405 -OEChem-04232416372D 76 81 0 1 0 0 0 0 0999 V2000 6.3966 -2.8100 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 13.3248 5.1900 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -5.8100 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 5.1900 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 4.6900 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -1.8100 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 1.5564 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 3.1900 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -0.3100 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 3.4947 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 3.1900 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -1.8100 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 1.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 2.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 2.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 1.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 3.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.6900 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 6.3966 0.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 0.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 1.8853 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 2.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 4.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 3.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 0.9333 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1397 4.4452 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -1.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 2.5986 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 0.8180 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 1.6562 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 3.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 4.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 3.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 0.6448 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -3.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -3.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 5.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4587 3.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -4.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -4.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4587 4.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -4.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.6074 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 2.2977 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 1.7726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 1.0823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 1.0823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.7726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 4.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 0.2977 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 -0.3926 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 -0.3926 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 0.2977 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8732 4.5823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4746 5.2726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 0.4356 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7290 4.6379 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9471 5.0346 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5504 4.2526 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 3.1046 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 0.2509 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 2.5700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 5.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6655 -1.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1897 5.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 2.5700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 0.8996 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 0.0796 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 0.3900 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -3.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 5.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.9957 3.3800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7256 -4.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -4.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 37 1 0 0 0 0 2 43 1 0 0 0 0 3 44 1 0 0 0 0 4 24 1 0 0 0 0 4 65 1 0 0 0 0 5 25 2 0 0 0 0 6 28 2 0 0 0 0 7 31 1 0 0 0 0 7 36 1 0 0 0 0 8 15 1 0 0 0 0 8 19 1 0 0 0 0 8 25 1 0 0 0 0 9 20 1 0 0 0 0 9 21 1 0 0 0 0 9 28 1 0 0 0 0 10 18 1 0 0 0 0 10 23 1 0 0 0 0 10 27 1 0 0 0 0 11 25 1 0 0 0 0 11 32 1 0 0 0 0 11 64 1 0 0 0 0 12 28 1 0 0 0 0 12 33 1 0 0 0 0 12 66 1 0 0 0 0 13 14 1 0 0 0 0 13 15 1 0 0 0 0 13 16 1 0 0 0 0 13 17 1 0 0 0 0 14 18 2 0 0 0 0 14 22 1 0 0 0 0 15 45 1 0 0 0 0 15 46 1 0 0 0 0 16 20 1 0 0 0 0 16 47 1 0 0 0 0 16 48 1 0 0 0 0 17 21 1 0 0 0 0 17 49 1 0 0 0 0 17 50 1 0 0 0 0 18 19 1 0 0 0 0 19 24 1 6 0 0 0 19 51 1 0 0 0 0 20 52 1 0 0 0 0 20 53 1 0 0 0 0 21 54 1 0 0 0 0 21 55 1 0 0 0 0 22 23 2 0 0 0 0 22 26 1 0 0 0 0 23 29 1 0 0 0 0 24 56 1 0 0 0 0 24 57 1 0 0 0 0 26 30 2 0 0 0 0 26 58 1 0 0 0 0 27 59 1 0 0 0 0 27 60 1 0 0 0 0 27 61 1 0 0 0 0 29 31 2 0 0 0 0 29 62 1 0 0 0 0 30 31 1 0 0 0 0 30 63 1 0 0 0 0 32 34 2 0 0 0 0 32 35 1 0 0 0 0 33 37 2 0 0 0 0 33 38 1 0 0 0 0 34 39 1 0 0 0 0 34 67 1 0 0 0 0 35 40 2 0 0 0 0 35 68 1 0 0 0 0 36 69 1 0 0 0 0 36 70 1 0 0 0 0 36 71 1 0 0 0 0 37 41 1 0 0 0 0 38 42 2 0 0 0 0 38 72 1 0 0 0 0 39 43 2 0 0 0 0 39 73 1 0 0 0 0 40 43 1 0 0 0 0 40 74 1 0 0 0 0 41 44 2 0 0 0 0 41 75 1 0 0 0 0 42 44 1 0 0 0 0 42 76 1 0 0 0 0 M END > 60192405 > 1 > 1030 > 7 > 3 > 4 > AAADcfB/uYAAAAAAAAAAAAAAAAAAAWAAAAA8eMECAAAAAFgB9AAAHwAQCAAADizhng4zxvPMFgCoAyRiVACCiCAhIiAI2CA+bJiOduLEsZuUcChu1hvY6CeQ0PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > (1R)-N1'-(2,4-difluorophenyl)-N2-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-N1'-(2,4-difluorophenyl)-N2-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-1-N'-(2,4-difluorophenyl)-2-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-1-N'-(2,4-difluorophenyl)-2-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-N1'-[2,4-bis(fluoranyl)phenyl]-N2-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-N-(2,4-difluorophenyl)-N'-(4-fluorophenyl)-7-methoxy-9-methyl-1-methylol-spiro[1,3-dihydro-beta-carboline-4,4'-piperidine]-1',2-dicarboxamide > InChI=1S/C32H32F3N5O4/c1-38-26-16-22(44-2)8-9-23(26)28-29(38)27(17-41)40(31(43)36-21-6-3-19(33)4-7-21)18-32(28)11-13-39(14-12-32)30(42)37-25-10-5-20(34)15-24(25)35/h3-10,15-16,27,41H,11-14,17-18H2,1-2H3,(H,36,43)(H,37,42)/t27-/m0/s1 > MIAWTIKZFBQFAR-MHZLTWQESA-N > 3.5 > 607.24063901 > C32H32F3N5O4 > 607.6 > CN1C2=C(C=CC(=C2)OC)C3=C1C(N(CC34CCN(CC4)C(=O)NC5=C(C=C(C=C5)F)F)C(=O)NC6=CC=C(C=C6)F)CO > CN1C2=C(C=CC(=C2)OC)C3=C1[C@@H](N(CC34CCN(CC4)C(=O)NC5=C(C=C(C=C5)F)F)C(=O)NC6=CC=C(C=C6)F)CO > 99.1 > 607.24063901 > 0 > 44 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 10 18 8 10 23 8 14 18 8 14 22 8 19 24 6 22 23 8 22 26 8 23 29 8 26 30 8 29 31 8 30 31 8 32 34 8 32 35 8 33 37 8 33 38 8 34 39 8 35 40 8 37 41 8 38 42 8 39 43 8 40 43 8 41 44 8 42 44 8 $$$$