60190499 -OEChem-04232405362D 73 78 0 1 0 0 0 0 0999 V2000 13.3248 4.6900 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 4.6900 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 4.1900 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -2.3100 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 1.0564 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 2.6900 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -0.8100 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 2.9947 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 2.6900 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.3100 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 1.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 1.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 0.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 0.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 2.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.1900 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 6.3966 -0.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -0.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 1.3853 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 2.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 4.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 3.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 0.4333 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -1.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 2.0986 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 0.3180 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 1.1562 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 3.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -3.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 2.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 4.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 0.1448 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -3.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -3.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4587 3.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 4.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -4.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -4.8100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4587 4.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -5.3100 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.1074 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 1.7977 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 1.2726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 0.5823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 0.5823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.2726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 3.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 -0.2023 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 -0.8926 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 -0.8926 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 -0.2023 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2577 3.5840 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8732 4.0823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4746 4.7726 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 -0.0644 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 2.6046 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 -0.2491 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 2.0700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 5.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6655 -2.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 2.0700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1897 4.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 0.3996 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 -0.4204 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 -0.1100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -3.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7256 -3.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.9957 2.8800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 5.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -5.1200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7256 -5.1200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -5.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 40 1 0 0 0 0 2 22 1 0 0 0 0 2 60 1 0 0 0 0 3 23 2 0 0 0 0 4 25 2 0 0 0 0 5 28 1 0 0 0 0 5 33 1 0 0 0 0 6 13 1 0 0 0 0 6 17 1 0 0 0 0 6 23 1 0 0 0 0 7 18 1 0 0 0 0 7 19 1 0 0 0 0 7 25 1 0 0 0 0 8 16 1 0 0 0 0 8 21 1 0 0 0 0 8 53 1 0 0 0 0 9 23 1 0 0 0 0 9 29 1 0 0 0 0 9 59 1 0 0 0 0 10 25 1 0 0 0 0 10 30 1 0 0 0 0 10 61 1 0 0 0 0 11 12 1 0 0 0 0 11 13 1 0 0 0 0 11 14 1 0 0 0 0 11 15 1 0 0 0 0 12 16 2 0 0 0 0 12 20 1 0 0 0 0 13 42 1 0 0 0 0 13 43 1 0 0 0 0 14 18 1 0 0 0 0 14 44 1 0 0 0 0 14 45 1 0 0 0 0 15 19 1 0 0 0 0 15 46 1 0 0 0 0 15 47 1 0 0 0 0 16 17 1 0 0 0 0 17 22 1 6 0 0 0 17 48 1 0 0 0 0 18 49 1 0 0 0 0 18 50 1 0 0 0 0 19 51 1 0 0 0 0 19 52 1 0 0 0 0 20 21 2 0 0 0 0 20 24 1 0 0 0 0 21 26 1 0 0 0 0 22 54 1 0 0 0 0 22 55 1 0 0 0 0 24 27 2 0 0 0 0 24 56 1 0 0 0 0 26 28 2 0 0 0 0 26 57 1 0 0 0 0 27 28 1 0 0 0 0 27 58 1 0 0 0 0 29 31 2 0 0 0 0 29 32 1 0 0 0 0 30 34 2 0 0 0 0 30 35 1 0 0 0 0 31 36 1 0 0 0 0 31 62 1 0 0 0 0 32 37 2 0 0 0 0 32 63 1 0 0 0 0 33 64 1 0 0 0 0 33 65 1 0 0 0 0 33 66 1 0 0 0 0 34 38 1 0 0 0 0 34 67 1 0 0 0 0 35 39 2 0 0 0 0 35 68 1 0 0 0 0 36 40 2 0 0 0 0 36 69 1 0 0 0 0 37 40 1 0 0 0 0 37 70 1 0 0 0 0 38 41 2 0 0 0 0 38 71 1 0 0 0 0 39 41 1 0 0 0 0 39 72 1 0 0 0 0 41 73 1 0 0 0 0 M END > 60190499 > 1 > 918 > 5 > 4 > 4 > AAADcfB7uQAAAAAAAAAAAAAAAAAAAWAAAAA8eMECAAAAAFgB9AAAHwAQCAAADizhng4zxvPJlgCoAyRiVACCiCAhIiAImSA+bJiOduLEsZuUcChu1hvY6CeQ0PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > (1R)-N2-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-N1'-phenyl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-N2-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-N1'-phenylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-2-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1-N'-phenylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-2-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1-N'-phenylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-N2-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-N1'-phenyl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1',2-dicarboxamide > (1R)-N'-(4-fluorophenyl)-7-methoxy-1-methylol-N-phenyl-spiro[3,9-dihydro-1H-beta-carboline-4,4'-piperidine]-1',2-dicarboxamide > InChI=1S/C31H32FN5O4/c1-41-23-11-12-24-25(17-23)35-28-26(18-38)37(30(40)34-22-9-7-20(32)8-10-22)19-31(27(24)28)13-15-36(16-14-31)29(39)33-21-5-3-2-4-6-21/h2-12,17,26,35,38H,13-16,18-19H2,1H3,(H,33,39)(H,34,40)/t26-/m0/s1 > UWGQQLKVSXXWKW-SANMLTNESA-N > 3.4 > 557.24383268 > C31H32FN5O4 > 557.6 > COC1=CC2=C(C=C1)C3=C(N2)C(N(CC34CCN(CC4)C(=O)NC5=CC=CC=C5)C(=O)NC6=CC=C(C=C6)F)CO > COC1=CC2=C(C=C1)C3=C(N2)[C@@H](N(CC34CCN(CC4)C(=O)NC5=CC=CC=C5)C(=O)NC6=CC=C(C=C6)F)CO > 110 > 557.24383268 > 0 > 41 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 12 16 8 12 20 8 17 22 6 20 21 8 20 24 8 21 26 8 24 27 8 26 28 8 27 28 8 29 31 8 29 32 8 30 34 8 30 35 8 31 36 8 32 37 8 34 38 8 35 39 8 36 40 8 37 40 8 38 41 8 39 41 8 8 16 8 8 21 8 $$$$