60189868 -OEChem-05072407482D 66 71 0 1 0 0 0 0 0999 V2000 6.3966 -5.0171 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 4.3971 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -2.0171 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 0.7635 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -0.5171 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 2.3971 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 5.4503 2.7018 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.0171 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 0.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5555 0.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9697 0.1900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.3971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 1.3971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 2.8971 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 6.3966 2.3971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 1.0924 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 2.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 1.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -1.5171 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 0.1404 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 1.8056 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 2.3971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 0.0251 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 0.8634 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 2.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 1.3971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -3.0171 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 2.3971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 0.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 1.3971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -3.5171 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -3.5171 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -0.1481 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -4.5171 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -4.5171 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -5.0171 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1171 0.6284 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1171 -0.2484 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4081 -0.2484 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4081 0.6284 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 0.8145 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 1.5048 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 3.2071 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2577 3.2912 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3932 3.3720 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5961 3.3720 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0505 4.4797 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6520 3.7894 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 -0.3573 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 2.3117 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6655 -1.7071 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 -0.5420 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 5.0171 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 3.5171 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3237 1.0871 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1296 2.7071 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 0.2771 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1296 1.0871 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7256 -3.2071 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -3.2071 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 0.1068 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 -0.7133 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 -0.4029 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 -4.8271 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -5.6371 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 35 1 0 0 0 0 2 19 1 0 0 0 0 2 54 1 0 0 0 0 3 20 2 0 0 0 0 4 25 1 0 0 0 0 4 34 1 0 0 0 0 5 10 1 0 0 0 0 5 11 1 0 0 0 0 5 20 1 0 0 0 0 6 12 1 0 0 0 0 6 14 1 0 0 0 0 6 17 1 0 0 0 0 7 15 1 0 0 0 0 7 18 1 0 0 0 0 7 45 1 0 0 0 0 8 20 1 0 0 0 0 8 28 1 0 0 0 0 8 52 1 0 0 0 0 9 10 1 0 0 0 0 9 11 1 0 0 0 0 9 12 1 0 0 0 0 9 13 1 0 0 0 0 10 38 1 0 0 0 0 10 39 1 0 0 0 0 11 40 1 0 0 0 0 11 41 1 0 0 0 0 12 42 1 0 0 0 0 12 43 1 0 0 0 0 13 15 2 0 0 0 0 13 16 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 6 0 0 0 14 44 1 0 0 0 0 16 18 2 0 0 0 0 16 21 1 0 0 0 0 17 23 1 0 0 0 0 17 46 1 0 0 0 0 17 47 1 0 0 0 0 18 22 1 0 0 0 0 19 48 1 0 0 0 0 19 49 1 0 0 0 0 21 24 2 0 0 0 0 21 50 1 0 0 0 0 22 25 2 0 0 0 0 22 51 1 0 0 0 0 23 26 2 0 0 0 0 23 27 1 0 0 0 0 24 25 1 0 0 0 0 24 53 1 0 0 0 0 26 29 1 0 0 0 0 26 55 1 0 0 0 0 27 30 2 0 0 0 0 27 56 1 0 0 0 0 28 32 2 0 0 0 0 28 33 1 0 0 0 0 29 31 2 0 0 0 0 29 57 1 0 0 0 0 30 31 1 0 0 0 0 30 58 1 0 0 0 0 31 59 1 0 0 0 0 32 35 1 0 0 0 0 32 60 1 0 0 0 0 33 36 2 0 0 0 0 33 61 1 0 0 0 0 34 62 1 0 0 0 0 34 63 1 0 0 0 0 34 64 1 0 0 0 0 35 37 2 0 0 0 0 36 37 1 0 0 0 0 36 65 1 0 0 0 0 37 66 1 0 0 0 0 M END > 60189868 > 1 > 804 > 5 > 3 > 5 > AAADceB7sQAAAAAAAAAAAAAAAABYAWAAAAA8YMEAAAAAAFgB9AAAHwAQCAAADizhng4zxvPJlgCoAyRiVACCiCAhIiAImSA+bJiOduLE8ZuUcChu1hvY6CeQ0PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > (1R)-2-benzyl-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]-1'-carboxamide > (1R)-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-2-(phenylmethyl)-1'-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]carboxamide > (1R)-2-benzyl-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxyspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]-1'-carboxamide > (1R)-2-benzyl-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxyspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]-1'-carboxamide > (1R)-N-(3-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-2-(phenylmethyl)spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]-1'-carboxamide > (1R)-2-benzyl-N-(3-fluorophenyl)-7-methoxy-1-methylol-spiro[3,9-dihydro-1H-beta-carboline-4,3'-azetidine]-1'-carboxamide > InChI=1S/C29H29FN4O3/c1-37-22-10-11-23-24(13-22)32-27-25(15-35)33(14-19-6-3-2-4-7-19)16-29(26(23)27)17-34(18-29)28(36)31-21-9-5-8-20(30)12-21/h2-13,25,32,35H,14-18H2,1H3,(H,31,36)/t25-/m0/s1 > UAWCDJXFBGAITD-VWLOTQADSA-N > 3.3 > 500.22236896 > C29H29FN4O3 > 500.6 > COC1=CC2=C(C=C1)C3=C(N2)C(N(CC34CN(C4)C(=O)NC5=CC(=CC=C5)F)CC6=CC=CC=C6)CO > COC1=CC2=C(C=C1)C3=C(N2)[C@@H](N(CC34CN(C4)C(=O)NC5=CC(=CC=C5)F)CC6=CC=CC=C6)CO > 80.8 > 500.22236896 > 0 > 37 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 13 15 8 13 16 8 14 19 6 16 18 8 16 21 8 18 22 8 21 24 8 22 25 8 23 26 8 23 27 8 24 25 8 26 29 8 27 30 8 28 32 8 28 33 8 29 31 8 30 31 8 32 35 8 33 36 8 35 37 8 36 37 8 7 15 8 7 18 8 $$$$