60186787 -OEChem-05102405182D 76 81 0 1 0 0 0 0 0999 V2000 7.4355 -1.5600 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 13.4977 4.9400 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 4.9400 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.4355 -1.5600 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4355 -1.5600 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 4.4400 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5840 1.3064 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.7034 -4.5600 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 2.9400 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 -0.5600 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.6232 3.2447 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 10.0336 2.9400 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 1.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 1.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 1.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 2.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 3.4400 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 6.5695 -0.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -0.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6232 1.6353 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0396 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 4.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 3.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2159 0.6833 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0082 2.3486 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1869 0.5680 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5790 1.4062 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 -3.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -3.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8996 3.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 -4.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -4.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 -4.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8996 4.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7656 2.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 2.1182 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7656 4.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6316 3.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6316 4.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7034 -5.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3574 1.5226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9589 0.8323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 0.8323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 1.5226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 1.3574 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 2.0477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9724 3.7500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9589 0.0477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3574 -0.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 -0.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 0.0477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4306 3.8340 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0461 4.3323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6475 5.0226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5857 0.1856 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6501 2.8546 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9364 0.0009 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0336 2.3200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 5.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0325 -2.7500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8384 -2.7500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8384 -4.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 -5.1800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3627 4.7500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7656 2.3200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5033 2.4802 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6379 2.6215 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4967 1.7561 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7656 5.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.1686 3.1300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0834 -5.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7034 -6.1800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3234 -5.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 2 0 0 0 0 1 5 2 0 0 0 0 1 10 1 0 0 0 0 1 28 1 0 0 0 0 2 42 1 0 0 0 0 3 24 1 0 0 0 0 3 62 1 0 0 0 0 6 25 2 0 0 0 0 7 30 1 0 0 0 0 7 39 1 0 0 0 0 8 34 1 0 0 0 0 8 43 1 0 0 0 0 9 16 1 0 0 0 0 9 19 1 0 0 0 0 9 25 1 0 0 0 0 10 20 1 0 0 0 0 10 21 1 0 0 0 0 11 18 1 0 0 0 0 11 23 1 0 0 0 0 11 55 1 0 0 0 0 12 25 1 0 0 0 0 12 33 1 0 0 0 0 12 61 1 0 0 0 0 13 14 1 0 0 0 0 13 15 1 0 0 0 0 13 16 1 0 0 0 0 13 17 1 0 0 0 0 14 20 1 0 0 0 0 14 44 1 0 0 0 0 14 45 1 0 0 0 0 15 21 1 0 0 0 0 15 46 1 0 0 0 0 15 47 1 0 0 0 0 16 48 1 0 0 0 0 16 49 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 24 1 1 0 0 0 19 50 1 0 0 0 0 20 51 1 0 0 0 0 20 52 1 0 0 0 0 21 53 1 0 0 0 0 21 54 1 0 0 0 0 22 23 2 0 0 0 0 22 26 1 0 0 0 0 23 27 1 0 0 0 0 24 56 1 0 0 0 0 24 57 1 0 0 0 0 26 29 2 0 0 0 0 26 58 1 0 0 0 0 27 30 2 0 0 0 0 27 59 1 0 0 0 0 28 31 1 0 0 0 0 28 32 2 0 0 0 0 29 30 1 0 0 0 0 29 60 1 0 0 0 0 31 34 2 0 0 0 0 31 63 1 0 0 0 0 32 35 1 0 0 0 0 32 64 1 0 0 0 0 33 37 2 0 0 0 0 33 38 1 0 0 0 0 34 36 1 0 0 0 0 35 36 2 0 0 0 0 35 65 1 0 0 0 0 36 66 1 0 0 0 0 37 40 1 0 0 0 0 37 67 1 0 0 0 0 38 41 2 0 0 0 0 38 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 40 42 2 0 0 0 0 40 72 1 0 0 0 0 41 42 1 0 0 0 0 41 73 1 0 0 0 0 43 74 1 0 0 0 0 43 75 1 0 0 0 0 43 76 1 0 0 0 0 M END > 60186787 > 1 > 1080 > 8 > 3 > 6 > AAADcfB7uQBAAAAAAAAAAAAAAAAAAWAAAAA8eMECAAAAAFgB9AAAHwQQSAAADizh3g4zx/PJlgKoAyRiVHDCiDAhIiAImTg+bJiOduLEsZuUcChu1hvY6CeQ0PMPoAAABgACAABAAAAMAAQAAAAAAAAAAA== > (1S)-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1'-(3-methoxyphenyl)sulfonyl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-2-carboxamide > (1S)-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1'-(3-methoxyphenyl)sulfonyl-2-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]carboxamide > (1S)-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1'-(3-methoxyphenyl)sulfonylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-2-carboxamide > (1S)-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1'-(3-methoxyphenyl)sulfonylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-2-carboxamide > (1S)-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1'-(3-methoxyphenyl)sulfonyl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-2-carboxamide > (1S)-N-(4-fluorophenyl)-7-methoxy-1'-(3-methoxyphenyl)sulfonyl-1-methylol-spiro[3,9-dihydro-1H-beta-carboline-4,4'-piperidine]-2-carboxamide > InChI=1S/C31H33FN4O6S/c1-41-22-4-3-5-24(16-22)43(39,40)35-14-12-31(13-15-35)19-36(30(38)33-21-8-6-20(32)7-9-21)27(18-37)29-28(31)25-11-10-23(42-2)17-26(25)34-29/h3-11,16-17,27,34,37H,12-15,18-19H2,1-2H3,(H,33,38)/t27-/m1/s1 > RGUAGNJEWWRMDK-HHHXNRCGSA-N > 3.3 > 608.21048412 > C31H33FN4O6S > 608.7 > COC1=CC(=CC=C1)S(=O)(=O)N2CCC3(CC2)CN(C(C4=C3C5=C(N4)C=C(C=C5)OC)CO)C(=O)NC6=CC=C(C=C6)F > COC1=CC(=CC=C1)S(=O)(=O)N2CCC3(CC2)CN([C@@H](C4=C3C5=C(N4)C=C(C=C5)OC)CO)C(=O)NC6=CC=C(C=C6)F > 133 > 608.21048412 > 0 > 43 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 11 18 8 11 23 8 17 18 8 17 22 8 19 24 5 22 23 8 22 26 8 23 27 8 26 29 8 27 30 8 28 31 8 28 32 8 29 30 8 31 34 8 32 35 8 33 37 8 33 38 8 34 36 8 35 36 8 37 40 8 38 41 8 40 42 8 41 42 8 $$$$