60186724 -OEChem-04262400002D 75 80 0 1 0 0 0 0 0999 V2000 8.9946 -5.0600 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 13.3248 4.4400 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 4.4400 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 3.9400 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 0.8064 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 2.4400 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -1.0600 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 2.7447 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 2.4400 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 1.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 0.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 0.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 2.9400 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 6.3966 -0.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -0.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 1.1353 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 1.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -2.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 2.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 0.1833 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1397 3.6952 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 1.8486 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 0.0680 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 0.9062 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -3.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -2.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 2.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -4.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 -3.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7267 3.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -0.1052 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 4.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4587 2.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4587 3.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 1.0226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 0.3323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 0.3323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.0226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 0.8574 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 1.5477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 3.2500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 -0.4523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 -1.1426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 -1.1426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 -0.4523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8732 3.8323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4746 4.5226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6520 -1.9523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0505 -2.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 -0.3144 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7290 3.8879 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9471 4.2846 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5504 3.5026 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 2.3546 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 -0.4991 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 1.8200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 5.0600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5917 -3.8700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -1.4400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3976 -2.2500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3976 -3.8700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1897 4.2500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 1.8200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 0.1496 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 -0.6704 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 -0.3600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5927 5.0600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.9957 2.6300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 33 1 0 0 0 0 2 41 1 0 0 0 0 3 21 1 0 0 0 0 3 64 1 0 0 0 0 4 23 2 0 0 0 0 5 29 1 0 0 0 0 5 38 1 0 0 0 0 6 14 1 0 0 0 0 6 16 1 0 0 0 0 6 23 1 0 0 0 0 7 17 1 0 0 0 0 7 18 1 0 0 0 0 7 22 1 0 0 0 0 8 15 1 0 0 0 0 8 20 1 0 0 0 0 8 25 1 0 0 0 0 9 23 1 0 0 0 0 9 32 1 0 0 0 0 9 63 1 0 0 0 0 10 11 1 0 0 0 0 10 12 1 0 0 0 0 10 13 1 0 0 0 0 10 14 1 0 0 0 0 11 15 2 0 0 0 0 11 19 1 0 0 0 0 12 17 1 0 0 0 0 12 42 1 0 0 0 0 12 43 1 0 0 0 0 13 18 1 0 0 0 0 13 44 1 0 0 0 0 13 45 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 15 16 1 0 0 0 0 16 21 1 1 0 0 0 16 48 1 0 0 0 0 17 49 1 0 0 0 0 17 50 1 0 0 0 0 18 51 1 0 0 0 0 18 52 1 0 0 0 0 19 20 2 0 0 0 0 19 24 1 0 0 0 0 20 26 1 0 0 0 0 21 53 1 0 0 0 0 21 54 1 0 0 0 0 22 27 1 0 0 0 0 22 55 1 0 0 0 0 22 56 1 0 0 0 0 24 28 2 0 0 0 0 24 57 1 0 0 0 0 25 58 1 0 0 0 0 25 59 1 0 0 0 0 25 60 1 0 0 0 0 26 29 2 0 0 0 0 26 61 1 0 0 0 0 27 30 2 0 0 0 0 27 31 1 0 0 0 0 28 29 1 0 0 0 0 28 62 1 0 0 0 0 30 33 1 0 0 0 0 30 65 1 0 0 0 0 31 34 2 0 0 0 0 31 66 1 0 0 0 0 32 36 2 0 0 0 0 32 37 1 0 0 0 0 33 35 2 0 0 0 0 34 35 1 0 0 0 0 34 67 1 0 0 0 0 35 68 1 0 0 0 0 36 39 1 0 0 0 0 36 69 1 0 0 0 0 37 40 2 0 0 0 0 37 70 1 0 0 0 0 38 71 1 0 0 0 0 38 72 1 0 0 0 0 38 73 1 0 0 0 0 39 41 2 0 0 0 0 39 74 1 0 0 0 0 40 41 1 0 0 0 0 40 75 1 0 0 0 0 M END > 60186724 > 1 > 896 > 6 > 2 > 5 > AAADcfB/sYAAAAAAAAAAAAAAAAAAAWAAAAA8eMECAAAAAFgB9AAAHwAQCAAADizhng4zxvPMFgCoAyRiVACCiCAhIiAI2CA+bJiOduLEsZuUcChu1hvY6CeQ0PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > (1S)-N-(4-fluorophenyl)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-2-carboxamide > (1S)-N-(4-fluorophenyl)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-2-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]carboxamide > (1S)-N-(4-fluorophenyl)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-2-carboxamide > (1S)-N-(4-fluorophenyl)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-2-carboxamide > (1S)-N-(4-fluorophenyl)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-2-carboxamide > (1S)-1'-(3-fluorobenzyl)-N-(4-fluorophenyl)-7-methoxy-9-methyl-1-methylol-spiro[1,3-dihydro-beta-carboline-4,4'-piperidine]-2-carboxamide > InChI=1S/C32H34F2N4O3/c1-36-27-17-25(41-2)10-11-26(27)29-30(36)28(19-39)38(31(40)35-24-8-6-22(33)7-9-24)20-32(29)12-14-37(15-13-32)18-21-4-3-5-23(34)16-21/h3-11,16-17,28,39H,12-15,18-20H2,1-2H3,(H,35,40)/t28-/m1/s1 > FHTOGWFFKDCPTO-MUUNZHRXSA-N > 4.1 > 560.25989728 > C32H34F2N4O3 > 560.6 > CN1C2=C(C=CC(=C2)OC)C3=C1C(N(CC34CCN(CC4)CC5=CC(=CC=C5)F)C(=O)NC6=CC=C(C=C6)F)CO > CN1C2=C(C=CC(=C2)OC)C3=C1[C@H](N(CC34CCN(CC4)CC5=CC(=CC=C5)F)C(=O)NC6=CC=C(C=C6)F)CO > 70 > 560.25989728 > 0 > 41 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 11 15 8 11 19 8 16 21 5 19 20 8 19 24 8 20 26 8 24 28 8 26 29 8 27 30 8 27 31 8 28 29 8 30 33 8 31 34 8 32 36 8 32 37 8 33 35 8 34 35 8 36 39 8 37 40 8 39 41 8 40 41 8 8 15 8 8 20 8 $$$$