60185091 -OEChem-05062421152D 70 75 0 1 0 0 0 0 0999 V2000 8.9946 -5.0600 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 3.9400 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 4.4400 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 0.8064 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 2.4400 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -1.0600 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 2.7447 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 1.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 0.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 0.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 2.9400 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 6.3966 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -0.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -0.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 2.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 1.1353 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3607 1.5740 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8607 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 1.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -2.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 0.1833 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1397 3.6952 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 1.8486 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 0.0680 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 0.9062 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -3.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -2.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -4.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 -3.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -0.1052 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 0.8574 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 1.5477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 1.0226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 0.3323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 0.3323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.0226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 3.2500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0211 3.0389 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 -0.4523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 -1.1426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 -1.1426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 -0.4523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8857 1.1755 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8356 1.1755 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4433 2.2280 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9683 3.0506 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8732 3.8323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4746 4.5226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6520 -1.9523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0505 -2.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 -0.3144 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7290 3.8879 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9471 4.2846 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5504 3.5026 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 2.3546 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 -0.4991 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 5.0600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5917 -3.8700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 -1.4400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3976 -2.2500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3976 -3.8700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 0.1496 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 -0.6704 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 -0.3600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 33 1 0 0 0 0 2 18 2 0 0 0 0 3 23 1 0 0 0 0 3 63 1 0 0 0 0 4 30 1 0 0 0 0 4 36 1 0 0 0 0 5 9 1 0 0 0 0 5 13 1 0 0 0 0 5 18 1 0 0 0 0 6 16 1 0 0 0 0 6 17 1 0 0 0 0 6 24 1 0 0 0 0 7 14 1 0 0 0 0 7 22 1 0 0 0 0 7 26 1 0 0 0 0 8 9 1 0 0 0 0 8 10 1 0 0 0 0 8 11 1 0 0 0 0 8 12 1 0 0 0 0 9 37 1 0 0 0 0 9 38 1 0 0 0 0 10 14 2 0 0 0 0 10 19 1 0 0 0 0 11 16 1 0 0 0 0 11 39 1 0 0 0 0 11 40 1 0 0 0 0 12 17 1 0 0 0 0 12 41 1 0 0 0 0 12 42 1 0 0 0 0 13 14 1 0 0 0 0 13 23 1 1 0 0 0 13 43 1 0 0 0 0 15 18 1 0 0 0 0 15 20 1 0 0 0 0 15 21 1 0 0 0 0 15 44 1 0 0 0 0 16 45 1 0 0 0 0 16 46 1 0 0 0 0 17 47 1 0 0 0 0 17 48 1 0 0 0 0 19 22 2 0 0 0 0 19 25 1 0 0 0 0 20 21 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 21 51 1 0 0 0 0 21 52 1 0 0 0 0 22 27 1 0 0 0 0 23 53 1 0 0 0 0 23 54 1 0 0 0 0 24 29 1 0 0 0 0 24 55 1 0 0 0 0 24 56 1 0 0 0 0 25 28 2 0 0 0 0 25 57 1 0 0 0 0 26 58 1 0 0 0 0 26 59 1 0 0 0 0 26 60 1 0 0 0 0 27 30 2 0 0 0 0 27 61 1 0 0 0 0 28 30 1 0 0 0 0 28 62 1 0 0 0 0 29 31 2 0 0 0 0 29 32 1 0 0 0 0 31 33 1 0 0 0 0 31 64 1 0 0 0 0 32 34 2 0 0 0 0 32 65 1 0 0 0 0 33 35 2 0 0 0 0 34 35 1 0 0 0 0 34 66 1 0 0 0 0 35 67 1 0 0 0 0 36 68 1 0 0 0 0 36 69 1 0 0 0 0 36 70 1 0 0 0 0 M END > 60185091 > 1 > 801 > 5 > 1 > 5 > AAADcfB7MQAAAAAAAAAAAAAAGAAAAWAAAAA8eIEAAAAAAFgB9AAAHwAACAAADyzhng4yxvMMFgCoAyVyVACCiCAhIiAI2CE+bJgOdvLEsZuUcChmxhnY6AeQ0PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > cyclopropyl-[(1S)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-2-yl]methanone > cyclopropyl-[(1S)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-2-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]yl]methanone > cyclopropyl-[(1S)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-2-yl]methanone > cyclopropyl-[(1S)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-2-yl]methanone > cyclopropyl-[(1S)-1'-[(3-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-2-yl]methanone > cyclopropyl-[(1S)-1'-(3-fluorobenzyl)-7-methoxy-9-methyl-1-methylol-spiro[1,3-dihydro-beta-carboline-4,4'-piperidine]-2-yl]methanone > InChI=1S/C29H34FN3O3/c1-31-24-15-22(36-2)8-9-23(24)26-27(31)25(17-34)33(28(35)20-6-7-20)18-29(26)10-12-32(13-11-29)16-19-4-3-5-21(30)14-19/h3-5,8-9,14-15,20,25,34H,6-7,10-13,16-18H2,1-2H3/t25-/m1/s1 > JYNWHADBVHDRHI-RUZDIDTESA-N > 3.1 > 491.25842012 > C29H34FN3O3 > 491.6 > CN1C2=C(C=CC(=C2)OC)C3=C1C(N(CC34CCN(CC4)CC5=CC(=CC=C5)F)C(=O)C6CC6)CO > CN1C2=C(C=CC(=C2)OC)C3=C1[C@H](N(CC34CCN(CC4)CC5=CC(=CC=C5)F)C(=O)C6CC6)CO > 57.9 > 491.25842012 > 0 > 36 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 10 14 8 10 19 8 13 23 5 19 22 8 19 25 8 22 27 8 25 28 8 27 30 8 28 30 8 29 31 8 29 32 8 31 33 8 32 34 8 33 35 8 34 35 8 7 14 8 7 22 8 $$$$