60185078 -OEChem-03292407202D 60 64 0 1 0 0 0 0 0999 V2000 7.4355 -4.5600 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 3.9400 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 -3.0600 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5840 0.3064 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 1.9400 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 7.4355 -1.5600 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.6232 2.2447 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 0.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 -0.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -0.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 2.4400 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 6.5695 1.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 -1.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -1.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6232 0.6353 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0396 1.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 3.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2159 -0.3167 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0082 1.3486 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1869 -0.4320 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5790 0.4062 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -3.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -4.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 -4.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0336 -3.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 1.1182 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0336 -4.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 0.3574 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 1.0477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3574 0.5226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9589 -0.1677 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 -0.1677 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 0.5226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9724 2.7500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9589 -0.9523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3574 -1.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 -1.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 -0.9523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4306 2.8340 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2234 4.0226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8249 3.3323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4775 1.9031 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7045 2.7500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8575 2.9769 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5857 -0.8144 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6501 1.8546 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9364 -0.9991 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 4.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 -1.9400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 -5.1800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5705 -2.7500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5033 1.4802 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6379 1.6215 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4967 0.7561 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5705 -4.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 27 1 0 0 0 0 2 19 1 0 0 0 0 2 53 1 0 0 0 0 3 22 2 0 0 0 0 4 25 1 0 0 0 0 4 31 1 0 0 0 0 5 9 1 0 0 0 0 5 13 1 0 0 0 0 5 20 1 0 0 0 0 6 15 1 0 0 0 0 6 16 1 0 0 0 0 6 22 1 0 0 0 0 7 14 1 0 0 0 0 7 18 1 0 0 0 0 7 44 1 0 0 0 0 8 9 1 0 0 0 0 8 10 1 0 0 0 0 8 11 1 0 0 0 0 8 12 1 0 0 0 0 9 33 1 0 0 0 0 9 34 1 0 0 0 0 10 14 2 0 0 0 0 10 17 1 0 0 0 0 11 15 1 0 0 0 0 11 35 1 0 0 0 0 11 36 1 0 0 0 0 12 16 1 0 0 0 0 12 37 1 0 0 0 0 12 38 1 0 0 0 0 13 14 1 0 0 0 0 13 19 1 6 0 0 0 13 39 1 0 0 0 0 15 40 1 0 0 0 0 15 41 1 0 0 0 0 16 42 1 0 0 0 0 16 43 1 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 18 23 1 0 0 0 0 19 45 1 0 0 0 0 19 46 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 20 49 1 0 0 0 0 21 24 2 0 0 0 0 21 50 1 0 0 0 0 22 26 1 0 0 0 0 23 25 2 0 0 0 0 23 51 1 0 0 0 0 24 25 1 0 0 0 0 24 52 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 2 0 0 0 0 28 30 1 0 0 0 0 28 54 1 0 0 0 0 29 32 1 0 0 0 0 29 55 1 0 0 0 0 30 32 2 0 0 0 0 30 56 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 31 59 1 0 0 0 0 32 60 1 0 0 0 0 M END > 60185078 > 1 > 685 > 5 > 2 > 3 > AAADceB7MQAAAAAAAAAAAAAAAAAAAWAAAAA8eIEAAAAAAFgB9AAAHwAQCAAADizhng4yxvPJlgCoAyVyVACCiCAlIiAImSE+bNgOdvLEtZuUcShm1hnY6YeY2POPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > (2-fluorophenyl)-[(1R)-1-(hydroxymethyl)-7-methoxy-2-methyl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-yl]methanone > (2-fluorophenyl)-[(1R)-1-(hydroxymethyl)-7-methoxy-2-methyl-1'-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]yl]methanone > (2-fluorophenyl)-[(1R)-1-(hydroxymethyl)-7-methoxy-2-methylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-yl]methanone > (2-fluorophenyl)-[(1R)-1-(hydroxymethyl)-7-methoxy-2-methylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-yl]methanone > (2-fluorophenyl)-[(1R)-1-(hydroxymethyl)-7-methoxy-2-methyl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-yl]methanone > (2-fluorophenyl)-[(1R)-7-methoxy-2-methyl-1-methylol-spiro[3,9-dihydro-1H-beta-carboline-4,4'-piperidine]-1'-yl]methanone > InChI=1S/C25H28FN3O3/c1-28-15-25(9-11-29(12-10-25)24(31)17-5-3-4-6-19(17)26)22-18-8-7-16(32-2)13-20(18)27-23(22)21(28)14-30/h3-8,13,21,27,30H,9-12,14-15H2,1-2H3/t21-/m0/s1 > KJWDLSLNDXZUDM-NRFANRHFSA-N > 2.8 > 437.21146993 > C25H28FN3O3 > 437.5 > CN1CC2(CCN(CC2)C(=O)C3=CC=CC=C3F)C4=C(C1CO)NC5=C4C=CC(=C5)OC > CN1CC2(CCN(CC2)C(=O)C3=CC=CC=C3F)C4=C([C@@H]1CO)NC5=C4C=CC(=C5)OC > 68.8 > 437.21146993 > 0 > 32 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 10 14 8 10 17 8 13 19 6 17 18 8 17 21 8 18 23 8 21 24 8 23 25 8 24 25 8 26 27 8 26 28 8 27 29 8 28 30 8 29 32 8 30 32 8 7 14 8 7 18 8 $$$$