60184907 -OEChem-05072402362D 77 82 0 1 0 0 0 0 0999 V2000 9.1675 0.4400 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 3.9400 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 -3.0600 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.0336 -4.0600 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5840 0.3064 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 1.9400 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 7.4355 -1.5600 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.6232 2.2447 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 0.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -0.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 -0.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 1.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 2.4400 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 8.3015 -1.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5695 -1.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6232 0.6353 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0396 1.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 3.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4355 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2159 -0.3167 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -3.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3126 3.1952 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0082 1.3486 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0336 1.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 -4.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 -2.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1869 -0.4320 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5790 0.4062 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1675 -4.5600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0336 -3.0600 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0336 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8996 2.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8996 0.4400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7656 1.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7656 0.9400 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 1.1182 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 0.3574 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 1.0477 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 -0.1677 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 0.5226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3574 0.5226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9589 -0.1677 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9724 2.7500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5136 -1.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9121 -0.9523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9589 -0.9523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3574 -1.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5661 2.9150 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7690 2.9150 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2234 4.0226 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8249 3.3323 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5857 -0.8144 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7646 -3.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9019 3.3879 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1200 3.7846 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7233 3.0026 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6501 1.8546 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6909 -3.9523 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0895 -4.6426 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5661 -2.0850 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7690 -2.0850 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9364 -0.9991 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3015 4.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7690 -5.0350 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5661 -5.0350 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6441 -3.1677 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2456 -2.4774 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8996 3.0600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8996 -0.1800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3026 2.2500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3026 0.6300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5033 1.4802 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6379 1.6215 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4967 0.7561 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 34 1 0 0 0 0 2 21 1 0 0 0 0 2 66 1 0 0 0 0 3 22 2 0 0 0 0 4 32 1 0 0 0 0 4 33 1 0 0 0 0 5 31 1 0 0 0 0 5 39 1 0 0 0 0 6 10 1 0 0 0 0 6 15 1 0 0 0 0 6 20 1 0 0 0 0 7 16 1 0 0 0 0 7 17 1 0 0 0 0 7 22 1 0 0 0 0 8 14 1 0 0 0 0 8 19 1 0 0 0 0 8 25 1 0 0 0 0 9 10 1 0 0 0 0 9 11 1 0 0 0 0 9 12 1 0 0 0 0 9 13 1 0 0 0 0 10 40 1 0 0 0 0 10 41 1 0 0 0 0 11 14 2 0 0 0 0 11 18 1 0 0 0 0 12 16 1 0 0 0 0 12 42 1 0 0 0 0 12 43 1 0 0 0 0 13 17 1 0 0 0 0 13 44 1 0 0 0 0 13 45 1 0 0 0 0 14 15 1 0 0 0 0 15 21 1 6 0 0 0 15 46 1 0 0 0 0 16 47 1 0 0 0 0 16 48 1 0 0 0 0 17 49 1 0 0 0 0 17 50 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 26 1 0 0 0 0 20 27 1 0 0 0 0 20 51 1 0 0 0 0 20 52 1 0 0 0 0 21 53 1 0 0 0 0 21 54 1 0 0 0 0 22 24 1 0 0 0 0 23 30 2 0 0 0 0 23 55 1 0 0 0 0 24 28 1 0 0 0 0 24 29 1 0 0 0 0 24 56 1 0 0 0 0 25 57 1 0 0 0 0 25 58 1 0 0 0 0 25 59 1 0 0 0 0 26 31 2 0 0 0 0 26 60 1 0 0 0 0 27 34 1 0 0 0 0 27 35 2 0 0 0 0 28 32 1 0 0 0 0 28 61 1 0 0 0 0 28 62 1 0 0 0 0 29 33 1 0 0 0 0 29 63 1 0 0 0 0 29 64 1 0 0 0 0 30 31 1 0 0 0 0 30 65 1 0 0 0 0 32 67 1 0 0 0 0 32 68 1 0 0 0 0 33 69 1 0 0 0 0 33 70 1 0 0 0 0 34 36 2 0 0 0 0 35 37 1 0 0 0 0 35 71 1 0 0 0 0 36 38 1 0 0 0 0 36 72 1 0 0 0 0 37 38 2 0 0 0 0 37 73 1 0 0 0 0 38 74 1 0 0 0 0 39 75 1 0 0 0 0 39 76 1 0 0 0 0 39 77 1 0 0 0 0 M END > 60184907 > 1 > 848 > 6 > 1 > 5 > AAADcfB7OQAAAAAAAAAAAAAAAAAAAWAAAAA8eJECAAAAAFgB9AAAHwAACAAADyzhng4yxvMMFgCoAyVyVACCiCAhIiAI2CE+bJgOdvLEsZuWcChmxhnY6Aey0PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > [(1R)-2-[(2-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1'-yl]-tetrahydropyran-4-yl-methanone > [(1R)-2-[(2-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-1'-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]yl]-(4-oxanyl)methanone > [(1R)-2-[(2-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1'-yl]-(oxan-4-yl)methanone > [(1R)-2-[(2-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methylspiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1'-yl]-(oxan-4-yl)methanone > [(1R)-2-[(2-fluorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]-1'-yl]-(oxan-4-yl)methanone > [(1R)-2-(2-fluorobenzyl)-7-methoxy-9-methyl-1-methylol-spiro[1,3-dihydro-beta-carboline-4,4'-piperidine]-1'-yl]-tetrahydropyran-4-yl-methanone > InChI=1S/C31H38FN3O4/c1-33-26-17-23(38-2)7-8-24(26)28-29(33)27(19-36)35(18-22-5-3-4-6-25(22)32)20-31(28)11-13-34(14-12-31)30(37)21-9-15-39-16-10-21/h3-8,17,21,27,36H,9-16,18-20H2,1-2H3/t27-/m0/s1 > GGVQAARRTIEONC-MHZLTWQESA-N > 2.9 > 535.28463486 > C31H38FN3O4 > 535.6 > CN1C2=C(C=CC(=C2)OC)C3=C1C(N(CC34CCN(CC4)C(=O)C5CCOCC5)CC6=CC=CC=C6F)CO > CN1C2=C(C=CC(=C2)OC)C3=C1[C@@H](N(CC34CCN(CC4)C(=O)C5CCOCC5)CC6=CC=CC=C6F)CO > 67.2 > 535.28463486 > 0 > 39 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 11 14 8 11 18 8 15 21 6 18 19 8 18 23 8 19 26 8 23 30 8 26 31 8 27 34 8 27 35 8 30 31 8 34 36 8 35 37 8 36 38 8 37 38 8 8 14 8 8 19 8 $$$$