60184259 -OEChem-05032416312D 64 68 0 1 0 0 0 0 0999 V2000 8.1286 4.4594 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -2.5406 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4110 0.8258 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.6286 -5.0794 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 2.4594 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 7.2626 -1.0406 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 2.7642 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -2.5406 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6286 -5.0794 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 0.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 1.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 1.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 0.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 0.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 2.9594 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 6.3966 2.4594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3966 -0.5406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -0.5406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4503 1.1547 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8667 1.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 3.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9946 2.9594 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0430 0.2027 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2626 -2.0406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8353 1.8680 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0140 0.0874 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4060 0.9257 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 -3.5406 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3196 -4.1284 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9376 -4.1284 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -0.0858 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3685 -3.8194 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8887 -3.8194 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 0.8768 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 1.5671 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 1.0420 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 0.3518 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 0.3518 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 1.0420 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7995 3.2694 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7860 -0.4329 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1845 -1.1232 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3406 -1.1232 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7392 -0.4329 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2577 3.3535 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0505 4.5420 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6520 3.8518 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3046 2.4225 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5316 3.2694 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6846 3.4964 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 -0.2949 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4771 2.3740 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7635 -0.4797 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1286 5.0794 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6655 -2.2306 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4348 0.1691 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7452 -0.6510 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5652 -0.3406 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5601 -3.2297 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7789 -3.6278 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1769 -4.4090 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0803 -4.4090 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4783 -3.6278 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6971 -3.2297 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 21 1 0 0 0 0 1 54 1 0 0 0 0 2 24 2 0 0 0 0 3 27 1 0 0 0 0 3 31 1 0 0 0 0 4 9 1 0 0 0 0 4 29 1 0 0 0 0 5 11 1 0 0 0 0 5 15 1 0 0 0 0 5 22 1 0 0 0 0 6 17 1 0 0 0 0 6 18 1 0 0 0 0 6 24 1 0 0 0 0 7 16 1 0 0 0 0 7 20 1 0 0 0 0 7 45 1 0 0 0 0 8 24 1 0 0 0 0 8 28 1 0 0 0 0 8 55 1 0 0 0 0 9 30 2 0 0 0 0 10 11 1 0 0 0 0 10 12 1 0 0 0 0 10 13 1 0 0 0 0 10 14 1 0 0 0 0 11 34 1 0 0 0 0 11 35 1 0 0 0 0 12 16 2 0 0 0 0 12 19 1 0 0 0 0 13 17 1 0 0 0 0 13 36 1 0 0 0 0 13 37 1 0 0 0 0 14 18 1 0 0 0 0 14 38 1 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 15 21 1 6 0 0 0 15 40 1 0 0 0 0 17 41 1 0 0 0 0 17 42 1 0 0 0 0 18 43 1 0 0 0 0 18 44 1 0 0 0 0 19 20 2 0 0 0 0 19 23 1 0 0 0 0 20 25 1 0 0 0 0 21 46 1 0 0 0 0 21 47 1 0 0 0 0 22 48 1 0 0 0 0 22 49 1 0 0 0 0 22 50 1 0 0 0 0 23 26 2 0 0 0 0 23 51 1 0 0 0 0 25 27 2 0 0 0 0 25 52 1 0 0 0 0 26 27 1 0 0 0 0 26 53 1 0 0 0 0 28 29 2 0 0 0 0 28 30 1 0 0 0 0 29 32 1 0 0 0 0 30 33 1 0 0 0 0 31 56 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 32 61 1 0 0 0 0 33 62 1 0 0 0 0 33 63 1 0 0 0 0 33 64 1 0 0 0 0 M END > 60184259 > 1 > 717 > 6 > 3 > 3 > AAADceB7uAAAAAAAAAAAAAAAAAAAAWLAAAA8WIAAAAAAAFgB/AAAHgAUCAAADizhngYzxvPZlgCpA6RyVgCCiCAlMiAomSG/fNqOdvrEsbuUcahu1pvY6WeQ0PMPoAAAAgACAABAAAAEAAQAAAAAAAAAAA== > (1R)-N-(3,5-dimethylisoxazol-4-yl)-1-(hydroxymethyl)-7-methoxy-2-methyl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1R)-N-(3,5-dimethyl-4-isoxazolyl)-1-(hydroxymethyl)-7-methoxy-2-methyl-1'-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]carboxamide > (1R)-N-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(hydroxymethyl)-7-methoxy-2-methylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1R)-N-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(hydroxymethyl)-7-methoxy-2-methylspiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1R)-N-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(hydroxymethyl)-7-methoxy-2-methyl-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4'-piperidine]-1'-carboxamide > (1R)-N-(3,5-dimethylisoxazol-4-yl)-7-methoxy-2-methyl-1-methylol-spiro[3,9-dihydro-1H-beta-carboline-4,4'-piperidine]-1'-carboxamide > InChI=1S/C24H31N5O4/c1-14-21(15(2)33-27-14)26-23(31)29-9-7-24(8-10-29)13-28(3)19(12-30)22-20(24)17-6-5-16(32-4)11-18(17)25-22/h5-6,11,19,25,30H,7-10,12-13H2,1-4H3,(H,26,31)/t19-/m0/s1 > XPFALIQJCJQKPN-IBGZPJMESA-N > 1.7 > 453.23760449 > C24H31N5O4 > 453.5 > CC1=C(C(=NO1)C)NC(=O)N2CCC3(CC2)CN(C(C4=C3C5=C(N4)C=C(C=C5)OC)CO)C > CC1=C(C(=NO1)C)NC(=O)N2CCC3(CC2)CN([C@H](C4=C3C5=C(N4)C=C(C=C5)OC)CO)C > 107 > 453.23760449 > 0 > 33 > 1 > 0 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 12 16 8 12 19 8 15 21 6 19 20 8 19 23 8 20 25 8 23 26 8 25 27 8 26 27 8 28 29 8 28 30 8 4 29 8 4 9 8 7 16 8 7 20 8 9 30 8 $$$$