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Compound Summary for: CID 5965


Also known as: DEMECARIUM BROMIDE, Humorsol, Frumtosnil, Tonilen, Tosmicil, Tosmilen, Tosmilene, Visumatic, Visumiotic
Molecular Formula: C32H52Br2N4O4   Molecular Weight: 716.58768   InChIKey: YHKBUDZECQDYBR-UHFFFAOYSA-L
Demecarium bromid is an indirect-acting parasympathomimetic agent that is used to treat glaucoma. It is a cholinesterase inhibitor or an anticholinesterase. Cholinesterase inhibitors prolong the effect of acetylcholine, which is released at the neuroeffector junction of parasympathetic postganglion nerves, by inactivating the cholinesterases that break it down. Demecarium inactivates both pseudocholinesterase and acetylcholinesterase. In the eye, this causes constriction of the iris sphincter muscle (causing miosis) and the ciliary muscle. The outflow of the aqueous humor is facilitated, which leads to a reduction in intraocular pressure.   From: DrugBank
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