59215864 -OEChem-04192422062D 76 80 0 1 0 0 0 0 0999 V2000 3.5981 -3.8776 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -4.8776 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 5.5981 -3.8776 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -0.3776 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 2.3660 -1.7436 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 3.3660 -0.0116 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 13.6492 4.8776 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 -0.8776 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 12.3923 3.6224 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 10.6603 2.6224 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 9.7942 1.1224 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 0.6224 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 12.3923 2.6224 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0 13.3385 2.3176 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5263 2.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5263 4.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.9221 3.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6603 3.6224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3385 3.9271 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 2.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 2.6224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 2.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 1.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -0.8776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 0.6224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 -0.3776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 2.6224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -1.3776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8301 -1.7436 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8301 -0.0116 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 1.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 3.6224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -0.8776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -2.3776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 2.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 -1.3776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -2.8776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 -2.3776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 4.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 4.1224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 2.6224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 3.6224 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -3.8776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 -0.8776 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4823 1.7772 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0875 1.7507 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.8759 2.0084 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1278 1.6474 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9248 1.6474 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9248 4.5973 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1278 4.5973 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3830 2.7076 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3830 3.5371 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4482 4.2050 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0497 3.5147 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 3.2424 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 0.0024 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2932 -2.0537 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1401 -2.2806 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3671 -1.4336 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3671 0.2984 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5201 0.5253 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2932 -0.3216 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6401 1.6593 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7932 1.4324 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0201 0.5854 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -0.2576 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0010 -2.6876 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 1.5024 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1951 -2.6876 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 4.7424 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3722 3.5854 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5991 4.4324 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7522 4.6593 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9272 2.3124 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9272 3.9324 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 43 1 0 0 0 0 2 43 1 0 0 0 0 3 43 1 0 0 0 0 4 44 1 0 0 0 0 5 44 1 0 0 0 0 6 44 1 0 0 0 0 7 19 2 0 0 0 0 8 26 2 0 0 0 0 9 13 1 0 0 0 0 9 16 1 0 0 0 0 9 19 1 0 0 0 0 10 15 1 0 0 0 0 10 18 1 0 0 0 0 10 20 1 0 0 0 0 11 20 2 0 0 0 0 11 25 1 0 0 0 0 12 23 1 0 0 0 0 12 26 1 0 0 0 0 12 31 1 0 0 0 0 13 14 1 0 0 0 0 13 15 1 0 0 0 0 13 45 1 0 0 0 0 14 17 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 15 48 1 0 0 0 0 15 49 1 0 0 0 0 16 18 1 0 0 0 0 16 50 1 0 0 0 0 16 51 1 0 0 0 0 17 19 1 0 0 0 0 17 52 1 0 0 0 0 17 53 1 0 0 0 0 18 54 1 0 0 0 0 18 55 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 56 1 0 0 0 0 22 23 1 0 0 0 0 22 27 1 0 0 0 0 23 25 2 0 0 0 0 24 26 1 0 0 0 0 24 28 1 0 0 0 0 24 29 1 0 0 0 0 24 30 1 0 0 0 0 25 57 1 0 0 0 0 27 32 1 0 0 0 0 27 35 2 0 0 0 0 28 33 2 0 0 0 0 28 34 1 0 0 0 0 29 58 1 0 0 0 0 29 59 1 0 0 0 0 29 60 1 0 0 0 0 30 61 1 0 0 0 0 30 62 1 0 0 0 0 30 63 1 0 0 0 0 31 64 1 0 0 0 0 31 65 1 0 0 0 0 31 66 1 0 0 0 0 32 39 2 0 0 0 0 32 40 1 0 0 0 0 33 36 1 0 0 0 0 33 67 1 0 0 0 0 34 37 2 0 0 0 0 34 68 1 0 0 0 0 35 41 1 0 0 0 0 35 69 1 0 0 0 0 36 38 2 0 0 0 0 36 44 1 0 0 0 0 37 38 1 0 0 0 0 37 43 1 0 0 0 0 38 70 1 0 0 0 0 39 42 1 0 0 0 0 39 71 1 0 0 0 0 40 72 1 0 0 0 0 40 73 1 0 0 0 0 40 74 1 0 0 0 0 41 42 2 0 0 0 0 41 75 1 0 0 0 0 42 76 1 0 0 0 0 M END > 59215864 > 1 > 1030 > 10 > 0 > 5 > AAADcfB/scAAAAAAAAAAAAAAAAAAAWAAAAA8eIEAAAAAAFgB0AAAHwAAAAAADijBmhQ/8JMIEACoAjd3dACCgCkxEiAJ2CE4dJiIYHLAnZGUIAhohgLIyCccicCPgAACAAAQAAAAAAQAACAAAAAAAAAAAA== > 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(o-tolyl)-6-(6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)-3-pyridyl]propanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)-3-pyridinyl]propanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)pyridin-3-yl]propanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)pyridin-3-yl]propanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(6-oxidanylidene-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)pyridin-3-yl]propanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-(6-keto-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)-4-(o-tolyl)-3-pyridyl]-N,2-dimethyl-propionamide > InChI=1S/C32H32F6N4O2/c1-19-7-5-6-8-24(19)25-16-27(41-11-12-42-23(18-41)9-10-28(42)43)39-17-26(25)40(4)29(44)30(2,3)20-13-21(31(33,34)35)15-22(14-20)32(36,37)38/h5-8,13-17,23H,9-12,18H2,1-4H3 > YFKZIDCOCYGNOA-UHFFFAOYSA-N > 6.4 > 618.24294525 > C32H32F6N4O2 > 618.6 > CC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN5C(C4)CCC5=O > CC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN5C(C4)CCC5=O > 56.8 > 618.24294525 > 0 > 44 > 0 > 1 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 11 20 8 11 25 8 13 45 3 20 21 8 21 22 8 22 23 8 23 25 8 27 32 8 27 35 8 28 33 8 28 34 8 32 39 8 33 36 8 34 37 8 35 41 8 36 38 8 37 38 8 39 42 8 41 42 8 $$$$