59215789 -OEChem-04262419552D 102106 0 1 0 0 0 0 0999 V2000 12.3923 0.0000 0.0000 Si 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 4.5000 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -0.0000 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 2.3660 -1.3660 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 3.3660 0.3660 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -4.5000 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 3.5981 -3.5000 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 5.5981 -3.5000 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 12.3923 1.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 -0.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 12.3923 4.0000 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 10.6603 3.0000 0.0000 N 0 0 3 0 0 0 0 0 0 0 0 0 9.7942 1.5000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 1.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 12.3923 3.0000 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0 11.5263 2.5000 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0 13.3385 2.6953 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3385 4.3047 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.9221 3.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5263 4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6603 4.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5263 1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 2.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3923 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3923 -0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3923 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3923 -2.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3923 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3923 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 2.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 4.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -0.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 2.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8301 -1.3660 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8301 0.3660 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 4.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -2.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -0.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -2.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7320 -2.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 -0.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -3.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4579 2.3835 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9893 2.1900 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0875 2.1284 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.8759 2.3860 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.8759 4.6140 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0875 4.8716 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3830 3.0853 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3830 3.9147 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9248 4.9750 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1278 4.9750 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4482 4.5826 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0497 3.8923 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9157 1.6077 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3142 0.9174 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3923 -0.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.0123 -0.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3923 0.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3923 0.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7723 0.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3923 -0.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 3.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7723 -2.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3923 -2.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0123 -2.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3923 -1.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 14.0123 -1.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3923 -0.3800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3923 -0.3800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7723 -1.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3923 -1.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 0.3800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 1.8800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6401 2.0369 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7932 1.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0201 0.9631 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 5.1200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3722 3.9631 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5991 4.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7522 5.0369 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9272 2.6900 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2932 -1.6760 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1401 -1.9030 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3671 -1.0560 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3671 0.6760 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5201 0.9030 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2932 0.0560 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0010 -2.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 0.1200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1951 -2.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 24 1 0 0 0 0 1 25 1 0 0 0 0 1 26 1 0 0 0 0 2 46 1 0 0 0 0 3 52 1 0 0 0 0 4 52 1 0 0 0 0 5 52 1 0 0 0 0 6 53 1 0 0 0 0 7 53 1 0 0 0 0 8 53 1 0 0 0 0 9 22 1 0 0 0 0 10 36 2 0 0 0 0 11 15 1 0 0 0 0 11 18 1 0 0 0 0 11 20 1 0 0 0 0 12 16 1 0 0 0 0 12 21 1 0 0 0 0 12 23 1 0 0 0 0 13 23 2 0 0 0 0 13 32 1 0 0 0 0 14 33 1 0 0 0 0 14 36 1 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 15 17 1 0 0 0 0 15 54 1 0 0 0 0 16 22 1 0 0 0 0 16 55 1 0 0 0 0 17 19 1 0 0 0 0 17 56 1 0 0 0 0 17 57 1 0 0 0 0 18 19 1 0 0 0 0 18 58 1 0 0 0 0 18 59 1 0 0 0 0 19 60 1 0 0 0 0 19 61 1 0 0 0 0 20 21 1 0 0 0 0 20 62 1 0 0 0 0 20 63 1 0 0 0 0 21 64 1 0 0 0 0 21 65 1 0 0 0 0 22 66 1 0 0 0 0 22 67 1 0 0 0 0 23 27 1 0 0 0 0 24 28 1 0 0 0 0 24 29 1 0 0 0 0 24 30 1 0 0 0 0 25 68 1 0 0 0 0 25 69 1 0 0 0 0 25 70 1 0 0 0 0 26 71 1 0 0 0 0 26 72 1 0 0 0 0 26 73 1 0 0 0 0 27 31 2 0 0 0 0 27 74 1 0 0 0 0 28 75 1 0 0 0 0 28 76 1 0 0 0 0 28 77 1 0 0 0 0 29 78 1 0 0 0 0 29 79 1 0 0 0 0 29 80 1 0 0 0 0 30 81 1 0 0 0 0 30 82 1 0 0 0 0 30 83 1 0 0 0 0 31 33 1 0 0 0 0 31 34 1 0 0 0 0 32 33 2 0 0 0 0 32 84 1 0 0 0 0 34 35 2 0 0 0 0 34 38 1 0 0 0 0 35 40 1 0 0 0 0 35 42 1 0 0 0 0 36 37 1 0 0 0 0 37 41 1 0 0 0 0 37 44 1 0 0 0 0 37 45 1 0 0 0 0 38 43 2 0 0 0 0 38 85 1 0 0 0 0 39 86 1 0 0 0 0 39 87 1 0 0 0 0 39 88 1 0 0 0 0 40 46 2 0 0 0 0 40 89 1 0 0 0 0 41 47 2 0 0 0 0 41 48 1 0 0 0 0 42 90 1 0 0 0 0 42 91 1 0 0 0 0 42 92 1 0 0 0 0 43 46 1 0 0 0 0 43 93 1 0 0 0 0 44 94 1 0 0 0 0 44 95 1 0 0 0 0 44 96 1 0 0 0 0 45 97 1 0 0 0 0 45 98 1 0 0 0 0 45 99 1 0 0 0 0 47 49 1 0 0 0 0 47100 1 0 0 0 0 48 50 2 0 0 0 0 48101 1 0 0 0 0 49 51 2 0 0 0 0 49 53 1 0 0 0 0 50 51 1 0 0 0 0 50 52 1 0 0 0 0 51102 1 0 0 0 0 M END > 59215789 > 1 > 1240 > 12 > 0 > 9 > AAADcfB/scgAAAAAAAAAAAAAAAAAAWAAAAA8eIEAAAAAAFgB0AAAHxAAAEAADijhuh5/8JMIEAGoAjd3dACCgCkxEiAJ2CE4dJiKYHLAnZGUIAhuhgLYyCeYyMCPgAACAAAQAAAAAAQAACAAAAAAAAAAAA== > 2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-[1-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-(4-fluoro-2-methyl-phenyl)-3-pyridyl]-N,2-dimethyl-propanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-[1-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-N,2-dimethylpropanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-[1-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-N,2-dimethylpropanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-[1-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-N,2-dimethylpropanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-[1-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-(4-fluoranyl-2-methyl-phenyl)pyridin-3-yl]-N,2-dimethyl-propanamide > 2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-[1-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-(4-fluoro-2-methyl-phenyl)-3-pyridyl]-N,2-dimethyl-propionamide > InChI=1S/C39H49F7N4O2Si/c1-24-17-28(40)12-13-29(24)30-21-34(50-16-15-49-14-10-11-31(49)33(50)23-52-53(8,9)36(2,3)4)47-22-32(30)48(7)35(51)37(5,6)25-18-26(38(41,42)43)20-27(19-25)39(44,45)46/h12-13,17-22,31,33H,10-11,14-16,23H2,1-9H3 > DNLURHMRJYUSCL-UHFFFAOYSA-N > 766.35130049 > C39H49F7N4O2Si > 766.9 > CC1=C(C=CC(=C1)F)C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN5CCCC5C4CO[Si](C)(C)C(C)(C)C > CC1=C(C=CC(=C1)F)C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN5CCCC5C4CO[Si](C)(C)C(C)(C)C > 48.9 > 766.35130049 > 0 > 53 > 0 > 2 > 0 > 0 > 0 > 1 > -1 > 1 5 255 > 13 23 8 13 32 8 15 17 3 16 22 3 23 27 8 27 31 8 31 33 8 32 33 8 34 35 8 34 38 8 35 40 8 38 43 8 40 46 8 41 47 8 41 48 8 43 46 8 47 49 8 48 50 8 49 51 8 50 51 8 $$$$